External Ids for SNX14 Gene
Previous GeneCards Identifiers for SNX14 Gene
This gene encodes a member of the sorting nexin family. Members of this family have a phox (PX) phosphoinositide binding domain and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Alternate splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
GeneCards Summary for SNX14 Gene
SNX14 (Sorting Nexin 14) is a Protein Coding gene. Diseases associated with SNX14 include intellectual disability-coarse face-macrocephaly-cerebellar hypotrophy syndrome. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX13.
UniProtKB/Swiss-Prot for SNX14 Gene
Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking.