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SNX14 Gene

protein-coding   GIFtS: 48
GCID: GC06M086215

Sorting Nexin 14

  Search for SNX14
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sorting Nexin 141 2
RGS-PX22
Sorting Nexin-142

External Ids:    HGNC: 149771   Entrez Gene: 572312   Ensembl: ENSG000001353177   UniProtKB: Q9Y5W73   

Export aliases for SNX14 gene to outside databases

Previous GC identifers: GC06U990242 GC06M086181 GC06M086210 GC06M086271 GC06M083439


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SNX14 Gene:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which
is a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein also
contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are
regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins.
Two transcript variants encoding distinct isoforms have been identified for this gene. (provided by RefSeq, Jul
2008)

GeneCards Summary for SNX14 Gene:
SNX14 (sorting nexin 14) is a protein-coding gene. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX13.

UniProtKB/Swiss-Prot: SNX14_HUMAN, Q9Y5W7
Function: May be involved in several stages of intracellular trafficking (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNX14 gene promoter:
         HOXA9   STAT5B   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   HNF-3beta   POU3F2   C/EBPalpha   MEF-2A   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNX14 promoter sequence
   Search Chromatin IP Primers for SNX14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNX14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14.3   Ensembl cytogenetic band:  6q14.3   HGNC cytogenetic band: 6q15

SNX14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX14 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M086215:  view genomic region     (about GC identifiers)

Start:
86,215,214 bp from pter      End:
86,303,874 bp from pter
Size:
88,661 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SNX14_HUMAN, Q9Y5W7 (See protein sequence)
Recommended Name: Sorting nexin-14  
Size: 946 amino acids; 110182 Da
Sequence caution: Sequence=CAI20444.1; Type=Erroneous gene model prediction; Sequence=CAI20445.1; Type=Erroneous
gene model prediction;
1 PDB 3D structure from and Proteopedia for SNX14:
4BGJ (3D)    
Secondary accessions: B4DI55 Q4VBR3 Q5TCF9 Q5TCG0 Q6NUI7 Q6PI37 Q9BSD1
Alternative splicing: 4 isoforms:  Q9Y5W7-1   Q9Y5W7-2   Q9Y5W7-3   Q9Y5W7-4   

Explore the universe of human proteins at neXtProt for SNX14: NX_Q9Y5W7

Explore proteomics data for SNX14 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys196, Lys213, Lys756
  • Modification sites at PhosphoSitePlus

  • See SNX14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_065201.1  NP_722523.1  

    ENSEMBL proteins: 
     ENSP00000257769   ENSP00000313121   ENSP00000420938   ENSP00000427380   ENSP00000358641  
     ENSP00000422814   ENSP00000425630   ENSP00000391981   ENSP00000358649   ENSP00000424302  
     ENSP00000425387   ENSP00000426806  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SNX: Sorting nexins

    5 InterPro protein domains:
     IPR016137 Regulat_G_prot_signal_superfam
     IPR000342 RGS_dom
     IPR013937 Sorting_nexin_C
     IPR001683 Phox
     IPR003114 Phox_assoc

    Graphical View of Domain Structure for InterPro Entry Q9Y5W7

    ProtoNet protein and cluster: Q9Y5W7

    3 Blocks protein domains:
    IPB000342 Regulator of G-protein signalling (RGS) protein signature
    IPB001683 Phox-like
    IPB013937 Sorting nexin


    UniProtKB/Swiss-Prot: SNX14_HUMAN, Q9Y5W7
    Similarity: Belongs to the sorting nexin family
    Similarity: Contains 1 PX (phox homology) domain
    Similarity: Contains 1 PXA domain
    Similarity: Contains 1 RGS domain


    Find genes that share domains with SNX14           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNX14_HUMAN, Q9Y5W7
    Function: May be involved in several stages of intracellular trafficking (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035091phosphatidylinositol binding IEA--
         
    Find genes that share ontologies with SNX14           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNX14
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    hsa-miR-922 hsa-miR-513a-3p hsa-miR-205* hsa-miR-548n
    SwitchGear 3'UTR luciferase reporter plasmidSNX14 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX14

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNX14_HUMAN, Q9Y5W7: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    golgi apparatus2
    cytosol1
    endoplasmic reticulum1
    lysosome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SNX14           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNX14
    Interactions:

        Search GeneGlobe Interaction Network for SNX14

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SNX14 (Q9Y5W73 ENSP000003131214) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HNF1AP208233I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007154cell communication ----
    GO:0015031protein transport IEA--
    GO:0038032termination of G-protein coupled receptor signaling pathway IEA--

    Find genes that share ontologies with SNX14           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNX14



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SNX14 gene (2 alternative transcripts): 
    NM_020468.3  NM_153816.3  

    Unigene Cluster for SNX14:

    Sorting nexin 14
    Hs.485871  [show with all ESTs]
    Unigene Representative Sequence: AK095380
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000346348(uc003pks.3) ENST00000314673(uc011dzg.2 uc003pkr.3 uc003pkt.3)
    ENST00000513865 ENST00000474645 ENST00000505648 ENST00000508980(uc003pkq.3)
    ENST00000369627 ENST00000503491(uc003pkp.3) ENST00000508658 ENST00000515216
    ENST00000418862 ENST00000369635 ENST00000503608 ENST00000506182 ENST00000514801
    ENST00000504191 ENST00000509338 ENST00000514419
    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate SNX14:
    hsa-miR-922 hsa-miR-513a-3p hsa-miR-205* hsa-miR-548n
    SwitchGear 3'UTR luciferase reporter plasmidSNX14 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SNX14
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SNX14 (NM_020468)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX14
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNX14
      QuantiTect SYBR Green Assays in human, mouse, rat SNX14
      QuantiFast Probe-based Assays in human, mouse, rat SNX14

    Additional mRNA sequence: 

    AF121863.1 AJ420561.1 AK000362.1 AK095380.1 AK125063.1 AK226097.1 AK293821.1 AK295417.1 
    AY044865.1 BC005110.1 BC046520.2 BC068589.1 BC095419.1 

    23 DOTS entries:

    DT.215001  DT.92437092  DT.101983722  DT.70103081  DT.121330173  DT.92437097  DT.121330088  DT.100008084 
    DT.121330095  DT.205961  DT.97844377  DT.121330218  DT.121330220  DT.75115257  DT.100889083  DT.121330079 
    DT.40206854  DT.100889091  DT.91642298  DT.91749441  DT.95264413  DT.97823974  DT.99982652 

    Selected AceView cDNA sequences (see all 467):

    BG179056 CA942653 AI191349 BM451217 BM751035 AK097191 AA911722 AW025846 
    BX643629 CR589962 BM829345 BG026689 AF121863 BU164891 AA629942 BM545943 
    CA445042 CK430482 BM455117 BM548708 BF173233 AI337035 CR605141 BU163883 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SNX14 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21a · 21b ·
    SP1:                                                                                                                                -     -                     
    SP2:                    -     -                                   -                                                                       -                     
    SP3:                    -     -                       -     -     -                                                                 -     -                     
    SP4:                          -     -                             -                                                                 -     -                     
    SP5:                    -     -                                   -                                                                                             

    ExUns: 21c ^ 22 ^ 23 ^ 24 ^ 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29 ^ 30a · 30b ^ 31 ^ 32a · 32b
    SP1:                                      -                       -                           
    SP2:                                      -                       -                           
    SP3:                                      -                       -                           
    SP4:                                      -                       -                           
    SP5:                                                                                          


    ECgene alternative splicing isoforms for SNX14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SNX14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTTCATTA
    SNX14 Expression
    About this image

    SNX14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNX14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.485871
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SNX14 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snx141 , 5 sorting nexin 141, 5 90.07(n)1
    97.44(a)1
      9 (47.24 cM)5
    2449621  NM_172926.31  NP_766514.21 
     883767475 
    chicken
    (Gallus gallus)
    Aves SNX141 sorting nexin 14 81.83(n)
    88.76(a)
      421832  NM_001039289.1  NP_001034378.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNX146
    sorting nexin 14
    82(a)
    1 ↔ 1
    1(176839453-176889165)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.210992 Xenopus laevis transcribed sequence with weak similarity more 77.61(n)    BX845195.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.257422 Transcribed sequence with weak similarity to protein more 71.47(n)    CK147430.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0123771 AgaP_AGAP012377 44.01(n)
    30.99(a)
      1280336  XM_320181.4  XP_320181.3 
    worm
    (Caenorhabditis elegans)
    Secernentea snx-141 snx-14 41.72(n)
    29.5(a)
      174997  NM_064443.5  NP_496844.3 


    ENSEMBL Gene Tree for SNX14 (if available)
    TreeFam Gene Tree for SNX14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SNX14 gene
    SNX132  SNX252  
    1 SIMAP similar gene for SNX14 using alignment to 9 protein entries:     SNX14_HUMAN (see all proteins):
    PXK

    Find genes that share paralogs with SNX14           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SNX14 (see all 1609)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs175312181,2
    C,F--86214781(+) CAGTGT/CTCTCA 2 -- ds50013Minor allele frequency- C:0.01NA 140
    rs1511396811,2
    --86214862(+) AACCTA/CATGCA 2 -- ds50010--------
    rs1115331401,2
    C--86215050(+) CTTGCT/CTAAAT 2 -- ds50011Minor allele frequency- C:0.00CSA 1
    rs1406210741,2
    --86215109(+) GAAACC/TTAGAG 2 -- ds50010--------
    rs1458742481,2
    --86215178(+) AACCCA/GTCAGA 2 -- ds50010--------
    rs1850209581,2
    --86215316(+) TAACTC/GTAAGA 2 -- ut310--------
    rs93510621,2
    C,F,H--86215343(+) CTGTTT/CCTCCA 2 -- ut31 ese34Minor allele frequency- C:0.01NS EA 418
    rs412716231,2
    C,F--86215383(+) CAATAC/TGAAGT 2 -- ut311Minor allele frequency- T:0.02NA 120
    rs1422007531,2
    C--86215430(+) AATTT-/TCTCTTT 2 -- ut310--------
    rs1413293781,2
    --86215480(+) ATTTGA/GATCAC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for SNX14 (86215214 - 86303874 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for SNX14:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676282CNV Deletion23128226
    nsv5383CNV Loss18451855
    nsv886334CNV Loss21882294
    nsv470839CNV Loss18288195
    nsv520112CNV Loss19592680
    nsv886333CNV Loss21882294
    nsv463939CNV Loss19166990
    nsv516516CNV Gain+Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SNX14 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with SNX14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A large family of endosome-localized proteins related to sorting nexin 1. (PubMed id 11485546)1, 2, 3 Teasdale R.D.... Gleeson P.A. (Biochem. J. 2001)
    2. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (Proteomics 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The Phox homology (PX) domain, a new player in phosphoinositide signalling. (PubMed id 11736640)1, 3 Xu Y....Hong W. (Biochem. J. 2001)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57231 HGNC: 14977 AceView: SYNCRIPandSNX14 Ensembl:ENSG00000135317 euGenes: HUgn57231
    ECgene: SNX14 H-InvDB: SNX14

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SNX14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SNX14 gene:
    Search GeneIP for patents involving SNX14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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