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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNX13 Gene

protein-coding   GIFtS: 54
GCID: GC07M017798

Sorting Nexin 13

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sorting Nexin 131 2
RGS Domain- And PHOX Domain-Containing Protein2 3
RGS-PX12 3
KIAA07133 5
Sorting Nexin-132

External Ids:    HGNC: 213351   Entrez Gene: 231612   Ensembl: ENSG000000711897   OMIM: 6065895   UniProtKB: Q9Y5W83   

Export aliases for SNX13 gene to outside databases

Previous GC identifers: GC07M017477 GC07M017576 GC07M017605


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SNX13 Gene:
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family
and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and
the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules
that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this
protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling.
Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of
its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
(provided by RefSeq, Jul 2008)

GeneCards Summary for SNX13 Gene: 
SNX13 (sorting nexin 13) is a protein-coding gene. Diseases associated with SNX13 include saethre-chotzen syndrome, and learning disability. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX25.

UniProtKB/Swiss-Prot: SNX13_HUMAN, Q9Y5W8
Function: May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis
(By similarity). Acts as a GAP for Galphas

Gene Wiki entry for SNX13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNX13 gene promoter:
         E2F-3a   E2F-4   NF-1/L   NF-1   E2F-5   E2F-2   LCR-F1   C/EBPalpha   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SNX13 promoter sequence
   Search SABiosciences Chromatin IP Primers for SNX13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNX13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.1   Ensembl cytogenetic band:  7p21.1   HGNC cytogenetic band: 7p21.1

SNX13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX13 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M017798:  view genomic region     (about GC identifiers)

Start:
17,830,385 bp from pter      End:
17,980,131 bp from pter
Size:
149,747 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 17,883,821-18,033,475     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SNX13_HUMAN, Q9Y5W8 (See protein sequence)
Recommended Name: Sorting nexin-13  
Size: 968 amino acids; 112189 Da
Subcellular location: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side
Sequence caution: Sequence=AAH22060.1; Type=Erroneous initiation; Sequence=BAA34433.1; Type=Frameshift;
Positions=887;
Secondary accessions: B2RCI9 O94821 Q8WVZ2 Q8WXH8
Alternative splicing: 2 isoforms:  Q9Y5W8-1   Q9Y5W8-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SNX13: NX_Q9Y5W8

Explore proteomics data for SNX13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y5W8

  • SNX13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SNX13 Protein Expression
    REFSEQ proteins: NP_055947.1  
    ENSEMBL proteins: 
     ENSP00000398789   ENSP00000386705   ENSP00000387053   ENSP00000397768   ENSP00000386639  

    Human Recombinant Protein Products for SNX13: 
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    Novus Biologicals SNX13 Lysates
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SNX13 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane ----
    GO:0005769early endosome IDA11729322
    GO:0031901early endosome membrane IEA--

    SNX13 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SNX: Sorting nexins

    5/6 InterPro protein domains (see all 6):
     IPR013996 PX_assoc_Snx13
     IPR000342 Regulat_G_prot_signal
     IPR016137 Regulat_G_prot_signal_superfam
     IPR013937 Sorting_nexin_C
     IPR001683 Phox

    Graphical View of Domain Structure for InterPro Entry Q9Y5W8

    ProtoNet protein and cluster: Q9Y5W8

    3 Blocks protein domains:
    IPB000342 Regulator of G-protein signalling (RGS) protein signature
    IPB003114 PX-associated
    IPB013937 Sorting nexin


    UniProtKB/Swiss-Prot: SNX13_HUMAN, Q9Y5W8
    Domain: The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate
    Similarity: Belongs to the sorting nexin family
    Similarity: Contains 1 PX (phox homology) domain
    Similarity: Contains 1 PXA domain
    Similarity: Contains 1 RGS domain


    SNX13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNX13_HUMAN, Q9Y5W8
    Function: May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis
    (By similarity). Acts as a GAP for Galphas

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004129cytochrome-c oxidase activity ----
    GO:0005515protein binding ----
    GO:0035091phosphatidylinositol binding IDA11729322
         
    SNX13 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SNX13:
     Increased gamma-H2AX phosphory 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Snx13):
     cardiovascular system  embryogenesis  growth/size  mortality/aging  nervous system 

    SNX13 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Snx13tm1.1Frq for SNX13

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SNX13 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SNX13

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNX13 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNX13 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNX13
    8/94 QIAGEN miScript miRNA Assays for microRNAs that regulate SNX13 (see all 94):
    hsa-miR-579 hsa-miR-323-3p hsa-miR-15a hsa-miR-3653 hsa-miR-371-5p hsa-miR-519a hsa-miR-4275 hsa-miR-502-3p
    SwitchGear 3'UTR luciferase reporter plasmidSNX13 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX13


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNX13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/8 Interacting proteins for SNX13 (Q9Y5W83 ENSP000003987894) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNASQ5JWF23, ENSP000003601414I2D: score=3 STRING: ENSP00000360141
    PAHP004393I2D: score=5 
    SOS1Q078893I2D: score=2 
    G6PCENSP000002538014STRING: ENSP00000253801
    KLF15ENSP000002962334STRING: ENSP00000296233
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IMP11729322
    GO:0007154cell communication IEA--
    GO:0038032termination of G-protein coupled receptor signaling pathway IEA--
    GO:0043547positive regulation of GTPase activity IDA11729322

    SNX13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SNX13 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNX13

    1 Novoseek inferred chemical compound relationship for SNX13 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 25.1 3 17353515 (2), 15469987 (1)

    Search CenterWatch for drugs/clinical trials and news about SNX13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SNX13 gene: 
    NM_015132.4  

    Unigene Cluster for SNX13:

    Sorting nexin 13
    Hs.487648  [show with all ESTs]
    Unigene Representative Sequence: NM_015132
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000428135 ENST00000409389(uc010kub.3 uc003stv.3 uc010kuc.3 uc003stw.1)
    ENST00000409076 ENST00000496855 ENST00000444712 ENST00000482558(uc003stx.1)
    ENST00000409604(uc003sty.3) ENST00000492626 ENST00000474067 ENST00000475800
    ENST00000498463 ENST00000494402 ENST00000471744
    miRNA
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    hsa-miR-579 hsa-miR-323-3p hsa-miR-15a hsa-miR-3653 hsa-miR-371-5p hsa-miR-519a hsa-miR-4275 hsa-miR-502-3p
    SwitchGear 3'UTR luciferase reporter plasmidSNX13 3' UTR sequence
    Inhib. RNA
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNX13
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNX13
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNX13

    Additional mRNA sequence: 

    AF121862.1 AK001861.1 AK023740.1 AK026643.1 AK294582.1 AK307453.1 AK315135.1 BC022060.1 
    BC041844.1 BC045667.1 BC050289.1 

    12 DOTS entries:

    DT.97776300  DT.40300158  DT.413316  DT.97843092  DT.121068465  DT.311647  DT.100794228  DT.438122 
    DT.449026  DT.91811944  DT.100657329  DT.91852266 

    24/236 AceView cDNA sequences (see all 236):

    W03727 AI014777 BF130541 AL705482 AB018256 CB241184 AW516924 AW474470 
    AI803722 AI784523 AW194236 CB148141 BM967158 BG504618 CA396783 AA044985 
    AA908770 BQ318883 CA446181 CB243335 AA814785 AK026643 AI828605 AI373797 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SNX13 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
    SP1:                                -     -                                   -                             -                                                   
    SP2:                                -     -                                   -                             -                                                   
    SP3:                                -                                         -                                                                                 
    SP4:                                -     -                                                                                                                     
    SP5:                                                                                                                                                            

    ExUns: 21a · 21b ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29
    SP1:  -                                                     -         
    SP2:                                                                  
    SP3:                                                                  
    SP4:                                                                  
    SP5:                                                                  


    ECgene alternative splicing isoforms for SNX13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNX13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTCCTGTAT
    SNX13 Expression
    About this image


    See SNX13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNX13

    SOURCE GeneReport for Unigene cluster: Hs.487648
        SABiosciences Custom PCR Arrays for SNX13
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SNX13 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snx131 , 5 sorting nexin 131, 5 93.07(n)1
    97.18(a)1
      12 (15.67 cM)5
    2174631  NM_001014973.21  NP_001014973.21 
     350471895 
    chicken
    (Gallus gallus)
    Aves SNX131 sorting nexin 13 84.81(n)
    91.95(a)
      420598  NM_001109755.1  NP_001103225.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNX136
    sorting nexin 13
    87(a)
    1 ↔ 1
    6(27926688-28005581)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.193642 Transcribed sequence with moderate similarity to protein more 79.57(n)    BX777948.1 
    zebrafish
    (Danio rerio)
    Actinopterygii snx131 sorting nexin 13 70.14(n)
    79.87(a)
      503733  XM_003200508.1  XP_003200556.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y116A8C.263
    CELE_Y116A8C.261
    Protein Y116A8C.261 33(a)3
    47.04(n)1
    35.59(a)1
      IV(17080005-17087486)3
    1784821  NM_070625.41  NP_503026.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MDM16
    Intermediate filament protein, required for nuclea...
    11(a)
    1 → many
    XIII(58939-62322)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G159001 phox domain-containing protein 41.07(n)
    26.53(a)
      816086  NM_127150.4  NP_179190.3 


    ENSEMBL Gene Tree for SNX13 (if available)
    TreeFam Gene Tree for SNX13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNX13 gene
    SNX252  SNX142  
    1 SIMAP similar gene for SNX13 using alignment to 7 protein entries:     SNX13_HUMAN (see all proteins):
    DKFZp761E0611

    SNX13 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2980 SNPs in SNX13 are shown (see all 2980)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1500577411,2
    --17829953(+) TAGAAC/GTTATC 1 -- ds50010--------
    rs1177705871,2
    C,F--17829986(+) GTTGAT/CACAGC 1 -- ds50011Minor allele frequency- C:0.02NA 120
    rs19655341,2
    C,F,A,H--17830112(-) AGATGG/AAAAGA 1 -- ds500112Minor allele frequency- A:0.32NA WA CSA EA 512
    rs1846399601,2
    --17830143(+) TTGATA/GCGATG 1 -- ds50010--------
    rs1902614151,2
    --17830144(+) TGATAC/TGATGA 1 -- ds50010--------
    rs1814756751,2
    --17830192(+) ATTTGC/TCCCAT 1 -- ds50010--------
    rs1145865951,2
    C,F--17830533(+) TTAGGC/TACACA 1 -- ut311Minor allele frequency- T:0.02WA 118
    rs46216971,2
    C,H--17830642(+) ATGCTC/TCTAAA 1 -- ut316Minor allele frequency- T:0.00NS EA NA 424
    rs1443996891,2
    C--17830737(+) AACAAC/TGGAAT 1 -- ut310--------
    rs1865762351,2
    --17830827(+) ACACAC/TGCATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SNX13 (17830385 - 17980131 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/14 variations for SNX13 (see all 14):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734070CNV Deletion23290073
    esv2734066CNV Deletion23290073
    esv2734068CNV Deletion23290073
    esv1984816CNV Deletion18987734
    esv2734069CNV Deletion23290073
    esv2463128CNV Deletion19546169
    esv993770CNV Deletion20482838
    esv2734067CNV Deletion23290073
    nsv365749CNV Loss16902084
    esv23642CNV Loss19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606589    OMIM disorders: --

    3 diseases for SNX13:    About MalaCards
    saethre-chotzen syndrome    learning disability    brachydactyly

    1 disease from the University of Copenhagen DISEASES database for SNX13:
    Acrocephalosyndactylia

    SNX13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SNX13
    Human Genome Epidemiology (HuGE) Navigator: SNX13 (1 document)

    Export disorders for SNX13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNX13 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with SNX13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking. (PubMed id 11729322)1, 2, 3, 9 Zheng B.... Farquhar M.G. (2001)
    2. A large family of endosome-localized proteins related to sorting nexin 1. (PubMed id 11485546)1, 2, 3 Teasdale R.D.... Gleeson P.A. (2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
    7. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
    8. Identification and characterisation of the gene TWIST NEIGHBOR (TWISTNB) located in the microdeletion syndrome 7p21 region. (PubMed id 12438708)1, 9 Kosan C. and Kunz J. (2002)
    9. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23161 HGNC: 21335 AceView: SNX13 Ensembl:ENSG00000071189 euGenes: HUgn23161
    ECgene: SNX13 H-InvDB: SNX13

    (According to HUGE)
    About This Section
    HUGE: KIAA0713

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNX13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SNX13 gene:
    Search GeneIP for patents involving SNX13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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