SNW1 Gene
protein-coding GIFtS: 63
GCID: GC14M078183
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|
SNW domain containing 1(Previous name: SKI interacting protein )
(Previous symbol: SKIIP)
| |
Aliases
for SNW1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SNW Domain Containing 11 2 | | Nuclear Receptor Coactivator NCoA-622 3 | | SKIIP1 2 3 | | Ski-Interacting Protein2 3 | | SKIP1 2 3 | | NCoA-621 | | Bx421 2 | | NCOA-622 | | PRPF451 2 | | Homolog Of Drosophila BX422 | | Prp451 2 | | Nuclear Receptor Coactivator, 62-KD2 | | SKI Interacting Protein1 2 | | SNW Domain-Containing Protein 12 | | Nuclear Protein SkiP2 3 | | |
Export aliases for SNW1 gene to outside databasesPrevious GC identifers: GC14M075689 GC14M072000 GC14M076173 GC14M077254 GC14M058349 |
Summaries
for SNW1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SNW1:
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol IIpromoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptorsto enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function asa splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specificgenes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with aregion of SKI oncoproteins that is required for transforming activity. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SNW1_HUMAN, Q13573Function: Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMADproteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, andretinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific mannerprobably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds tomultimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators suchas MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form atranscriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved intranscriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TARRNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter.Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA; thefunction probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. Maybe involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of theCCND1 gene and its mRNA
Gene Wiki entry for SNW1
|
Genomic Views
for SNW1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SNW1 gene promoter:
Pbx1a AML1a CUTL1 GATA-1 AREB6 POU2F1 POU2F1a POU2F1b POU2F1c Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for SNW1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNW1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q24.3 Ensembl cytogenetic band: 14q24.3 HGNC cytogenetic band: 14q22.1-q22.3SNW1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M078183: view genomic region
(about GC identifiers)
Start:
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78,183,942 bp from pter |
End:
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78,227,550 bp from pter |
Size:
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43,609 bases |
Orientation:
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minus strand |
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Proteins
for SNW1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SNW1_HUMAN, Q13573 (See
protein sequence)Recommended Name: SNW domain-containing protein 1 Size: 536 amino acids; 61494 Da
Subunit: Interacts SKI, SMAD2,SMAD3, RBPJ, RB1, PABPN1, MAGEA1, SIRT1, FOXN3, U2AF2, PPIL1, DAXX and ATP1B4. Interactswith VDR and RXRA; preferentially associates with VDR:RXRA heterodimers. Interacts with NCOR2 and EBV EBNA2; NCOR2 andEBV EBNA2 compete for interaction with SNW1. Interacts with MAML1. Interacts with NOTCH1 NICD; the interactioninvolves multimerized NOTCH1 NICD. Forms a complex with NOTCH1 NICD and MAML1; the association is dissociated by RBPJ.Identified in the spliceosome C complex. Associates with U4/U6-U5 tri-small nuclear ribonucleoproteins (U4/U6-U5tri-snRNPs). Associates with positive transcription elongation factor b (P-TEFb). Component of the SNARP complex whichconsists at least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN. Interacts with human papillomavirus type-16 (HPV16) E7protein
Subcellular location: Nucleus
Secondary accessions: A8K8A9 Q13483 Q32N03 Q5D0D6Explore the universe of human proteins at neXtProt for SNW1: NX_Q13573
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13573
SNW1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036377.1
ENSEMBL proteins: ENSP00000261531 ENSP00000452059 ENSP00000451741 ENSP00000451129 ENSP00000452473 Reactome Protein details: Q13573
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
SNW1 for ontologies About GeneDecksing
SNW1 Antibody Products:
Assay Products for SNW1: |
Protein
Domains /
Families
for SNW1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SNW1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13573ProtoNet protein and cluster: Q13573 1 Blocks protein family: IPB004015 SKIP/SNW domain
UniProtKB/Swiss-Prot: SNW1_HUMAN, Q13573Similarity: Belongs to the SNW family |
Function
for SNW1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SNW1_HUMAN, Q13573Function: Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMADproteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, andretinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific mannerprobably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds tomultimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators suchas MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form atranscriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved intranscriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TARRNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter.Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA; thefunction probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. Maybe involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of theCCND1 gene and its mRNA
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNW1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNW1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SNW1 (NM_012245) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNW1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNW1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNW1 |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
SNW1 for ontologies About GeneDecksing
14 GenomeRNAi human phenotypes for SNW1:
|
Pathways & Interactions
for SNW1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by NOTCH1 t(7 9)(NOTCH1:M1580_K2555) Translocation Mutant | | | 2 | Development_Notch Signaling Pathway | | | 3 | Generic Transcription Pathway | | | 4 | Development NOTCH1-mediated pathway for NF-KB activity modulation | | | 5 | Mature NOTCH heterodimer traffics to the plasma membrane | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for SNW1
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SNW1
2  GeneGo (Thomson Reuters) Pathways for SNW1
2  BioSystems Pathways for SNW1
5/17 
Reactome Pathways for SNW1 (see all 17)
2 
Kegg Pathways (Kegg details for SNW1):
SNW1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SNW1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/883 Interacting proteins for SNW1 (Q135731, 2, 3 ENSP000002615314) via UniProtKB, MINT, STRING, and/or I2D (see all 883)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| NCOR2 | Q9Y6181, 2, 3, ENSP000003485514 | EBI-632715,EBI-80830 MINT-7945693 I2D:
score=2 STRING: ENSP00000348551 | | HDAC2 | Q927692, 3, ENSP000003813314 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000381331 | | HSPA5 | P110212, 3, ENSP000003241734 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000324173 | | NCOR1 | O753762, 3, ENSP000002687124 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000268712 | | PRPF8 | Q6P2Q92, 3, ENSP000003043504 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000304350 |
About this table
Gene Ontology (GO): 5/20 biological process terms (GO ID links to tree view) (see all 20): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IDA | 14985122 | | GO:0000398 | mRNA splicing, via spliceosome |
IDA | 15194481 | | GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 9632709 | | GO:0006367 | transcription initiation from RNA polymerase II promoter |
TAS | -- | | GO:0007219 | Notch signaling pathway |
TAS | -- |
SNW1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SNW1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SNW1 for compounds About GeneDecksing
 Browse Tocris compounds for SNW1
2 Novoseek chemical compound relationships for SNW1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| vitamin d |
17.4 |
1 |
14985122 (1) |
| steroid |
12.8 |
1 |
12359070 (1) |
Search CenterWatch for drugs/clinical trials and news about SNW1
|
Transcripts
for SNW1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SNW1 gene: NM_012245.2 Unigene Cluster for SNW1: SNW domain containing 1 Hs.445498 [show with all ESTs]Unigene Representative Sequence: AF0451847 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000261531(uc001xuf.3 uc010tvm.2) ENST00000554775 ENST00000556428
ENST00000555761(uc010tvn.1) ENST00000553565 ENST00000554324 ENST00000557663
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNW1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNW1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SNW1 (NM_012245) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNW1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNW1 |
Additional cDNA sequence: AF045184.1 AK292274.1 AK293619.1 AK302246.1 AK316087.1 BC032377.2 BC040112.2 BC046105.2 BC051806.1 BC065286.1 BC105585.1 BC108902.1 BC108903.1 BT020060.1 BT020061.1 CR457433.1 U51432.1 16 DOTS entries: DT.100879259 DT.445417 DT.95308927 DT.100879277 DT.40263026 DT.100879268 DT.121399893 DT.97806586 DT.100879265 DT.100879267 DT.100879272 DT.101982632 DT.120787420 DT.92445691 DT.105857 DT.86858181 24/357 AceView cDNA sequences (see all 357): CB132015 AL546974 BQ063392 AI342765 BM785999 AU141036 BQ267387 CB053921 BM562642 BU152894 BX459523 BM479448 AA022934 BQ636821 BE466473 AA565621 BU069454 AU120325 BC046105 BC040112 BI494705 BM666723 F07556 AA490259
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for SNW1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SNW1
|
Expression
for SNW1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SNW1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGCCCCACA
About this image
See SNW1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SNW1
SOURCE GeneReport for Unigene cluster: Hs.445498
SABiosciences Expression via Pathway-Focused PCR Arrays including SNW1: | Notch Signaling Targets in human mouse rat | | Notch Signaling Pathway in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNW1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SNW1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNW1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNW1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNW1 |
Orthologs
for SNW1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SNW1 gene from 9/34 species (see all 34) About this table
ENSEMBL Gene Tree for SNW1 (if available)
TreeFam Gene Tree for SNW1 (if available) |
Paralogs
for SNW1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SNW1 gene
SNW1 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for SNW1
PGOHUM00000261864 PGOHUM00000261878 PGOHUM00000244767
|
Genomic Variants
for SNW1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SNW1 (78183942 - 78227550 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for SNW1
6 CNVs: 3943 49414 76681 87276 3056 8773 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNW1 |
|
Disorders
/ Diseases
for SNW1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SNW1 for disorders About GeneDecksing
OMIM gene information: 603055
OMIM disorders: --
9  diseases for SNW1: About MalaCardsoculopharyngeal muscular dystrophy muscular dystrophy retinoblastoma rabies
pancreatic cancer asthma pancreatitis malaria
neuronitis
1 Novoseek disease relationship for SNW1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| retinoblastoma |
39.7 |
2 |
15194481 (1), 14611687 (1) |
Human Genome Epidemiology (HuGE) Navigator: SNW1 (3 documents)
Export disorders for SNW1 gene to outside databases
|
Publications
for SNW1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SNW1 gene, integrated from 9 sources (see all 89):
(articles sorted by number of sources associating them with SNW1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation and characterization of a novel coactivator protein, NCoA- 62, involved in vitamin D-mediated transcription. (PubMed id 9632709)1, 2, 3 Baudino T.A.... Macdonald P.N. (1998)
- The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein. (PubMed id 20368803)1, 2, 9 Stegmann C.M....Wahl M.C. (2010)
- The human Ski-interacting protein functionally substitutes for the yeast PRP45 gene. (PubMed id 15194481)1, 2, 9 Figueroa J.D. and Hayman M.J. (2004)
- Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP. (PubMed id 16595688)1, 2, 9 Xu C.... Zhang Q. (2006)
- A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. (PubMed id 15905409)1, 2, 9 Bres V....Jones K.A. (2005)
- The product of an oculopharyngeal muscular dystrophy gene, poly(A)- binding protein 2, interacts with SKIP and stimulates muscle-specific gene expression. (PubMed id 11371506)1, 2, 9 Kim Y.-J....Arahata K. (2001)
- The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42. (PubMed id 9569025)1, 2, 9 Dahl R.... Hayman M.J. (1998)
- A large intrinsically disordered region in SKIP and i ts disorder-order transition induced by PPIL1 binding revealed by NMR. (PubMed id 20007319)1, 2, 9 Wang X....Shi Y. (2010)
- Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300. (PubMed id 14985122)1, 2, 9 Leong G.M....Gardiner E.M. (2004)
- SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation. (PubMed id 19818711)1, 2, 9 BrA"s V....Jones K.A. (2009)
|
External Searches for SNW1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SNW1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SNW1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SNW1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SNW1 gene:
Search GeneIP for patents involving SNW1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SNW1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for SNW1 | | OriGene shRNA RFP for SNW1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNW1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNW1 | | | OriGene Protein Over-expression Lysate for SNW1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SNW1 | | OriGene 3'-UTR Clone for SNW1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNW1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNW1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SNW1 | | OriGene Custom Protein Services for SNW1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNW1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNW1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNW1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNW1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNW1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNW1 |
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| | | | Search Tocris compounds for SNW1 |
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 | | | SNW1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNW1 |
|  |  |  | | | | ThermoFisher Antibodies for SNW1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNW1 |
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