Aliases for SNW1 Gene
Aliases for SNW1 Gene
External Ids for SNW1 Gene
- HGNC: 16696
- Entrez Gene: 22938
- Ensembl: ENSG00000100603
- OMIM: 603055
- UniProtKB: Q13573
Previous HGNC Symbols for SNW1 Gene
- SKIIP
Previous GeneCards Identifiers for SNW1 Gene
- GC14M075689
- GC14M072000
- GC14M076173
- GC14M077254
- GC14M078183
- GC14M058349
Summaries for SNW1 Gene
-
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for SNW1 Gene
SNW1 (SNW Domain Containing 1) is a Protein Coding gene. Among its related pathways are Signaling by NOTCH1 and Development NOTCH1-mediated pathway for NF-KB activity modulation. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity.
UniProtKB/Swiss-Prot for SNW1 Gene
-
Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3end of the CCND1 gene and its mRNA.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNW1 Gene
Genomics for SNW1 Gene
GeneHancer (GH) Regulatory Elements for SNW1 Gene
Regulatory Element Products
Genomic Locations for SNW1 Gene
- chr14:77,717,599-77,761,218
- (GRCh38/hg38)
- Size:
- 43,620 bases
- Orientation:
- Minus strand
- chr14:78,183,942-78,227,550
- (GRCh37/hg19)
Genomic View for SNW1 Gene
- Cytogenetic band:
-
- 14q24.3 by Ensembl
- 14q24.3 by Entrez Gene
- 14q24.3 by HGNC


RefSeq DNA sequence for SNW1 Gene
Proteins for SNW1 Gene
-
Protein details for SNW1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13573-SNW1_HUMAN
- Recommended name:
- SNW domain-containing protein 1
- Protein Accession:
- Q13573
- A8K8A9
- Q13483
- Q32N03
- Q5D0D6
Protein attributes for SNW1 Gene
- Size:
- 536 amino acids
- Molecular mass:
- 61494 Da
- Quaternary structure:
-
- Interacts SKI, SMAD2,SMAD3, RBPJ, RB1, PABPN1, MAGEA1, SIRT1, FOXN3, U2AF2, PPIL1, DAXX and ATP1B4. Interacts with VDR and RXRA; preferentially associates with VDR:RXRA heterodimers. Interacts with NCOR2 and EBV EBNA2; NCOR2 and EBV EBNA2 compete for interaction with SNW1. Interacts with MAML1. Interacts with NOTCH1 NICD; the interaction involves multimerized NOTCH1 NICD. Forms a complex with NOTCH1 NICD and MAML1; the association is dissociated by RBPJ. Identified in the spliceosome C complex. Associates with U4/U6-U5 tri-small nuclear ribonucleoproteins (U4/U6-U5 tri-snRNPs). Associates with positive transcription elongation factor b (P-TEFb). Component of the SNARP complex which consists at least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN. Interacts with human papillomavirus type-16 (HPV16) E7 protein.
Protein Expression for SNW1 Gene
Post-translational modifications for SNW1 Gene
- Ubiquitination at isoforms=193 and posLast=416416
Other Protein References for SNW1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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Assay Products
No data available for DME Specific Peptides for SNW1 Gene
Domains & Families for SNW1 Gene
Gene Families for SNW1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SNW1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for SNW1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q13573- Family:
-
- Belongs to the SNW family.
Function for SNW1 Gene
Molecular function for SNW1 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3end of the CCND1 gene and its mRNA.
Phenotypes From GWAS Catalog for SNW1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003713 | transcription coactivator activity | IDA | 11514567 |
GO:0003714 | transcription corepressor activity | IDA | 14985122 |
GO:0003723 | RNA binding | HDA,IDA | 22681889 |
GO:0005112 | Notch binding | IPI | 10713164 |
GO:0005515 | protein binding | IPI | 9569025 |
Phenotypes for SNW1 Gene
- GenomeRNAi human phenotypes for SNW1:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Negative genetic interaction between MUS81-/- and MUS81+/+
- shRNA abundance <= 50%
- Synthetic lethal with Ras
- Decreased shRNA abundance (Z-score < -2)
- Dynamic nuclei (hole, folded or small irregular)
- Increased shRNA abundance (Z-score > 2)
- Increased G1 DNA content
- G0/1 arrest
- Effect on mitosis
- Downregulation of NF-kappaB pathway after LMP1 stimulation
- Increased number of mitotic cells
- Decreased Salmonella enterica Typhimurium invasion
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Decreased homologous recombination repair frequency
- Decreased shRNA abundance
- Decreased influenza A/WSN/33 replication
- Decreased cell number
- Negative genetic interaction between BLM-/- and BLM+/+
- Decreased viability of wild-type and TP53 knockout cells
- Increased mitotic index
- Decreased centriole number
- Decreased HIV-1 infection
- Downregulation of NF-kappaB pathway after TNFalpha stimulation
- Decreased influenza A H1N1 (A/WSN/33) virus numbers
- Mitotic arrest, spindle defect
- Increased telomere dysfunction-induced foci (TIF) formation
Animal Model Products
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miRNA for SNW1 Gene
- miRTarBase miRNAs that target SNW1
-
- hsa-let-7c-5p (MIRT051793)
- hsa-mir-6749-3p (MIRT641529)
- hsa-mir-6792-3p (MIRT641530)
- hsa-mir-4691-5p (MIRT641531)
- hsa-mir-1304-3p (MIRT641532)
- hsa-mir-660-3p (MIRT641533)
- hsa-mir-5193 (MIRT641534)
- hsa-mir-1208 (MIRT641535)
- hsa-mir-6760-3p (MIRT641536)
- hsa-mir-141-5p (MIRT641537)
- hsa-mir-4318 (MIRT641538)
- hsa-mir-1273g-5p (MIRT790078)
- hsa-mir-203a-5p (MIRT790159)
- hsa-mir-3170 (MIRT790250)
- hsa-mir-5572 (MIRT790756)
- hsa-mir-6737-5p (MIRT790907)
- hsa-mir-6812-5p (MIRT790987)
- hsa-mir-6819-5p (MIRT790991)
- hsa-mir-6855-5p (MIRT791036)
- hsa-mir-92a-1-5p (MIRT791159)
miRNA Products
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNW1 Gene
Localization for SNW1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SNW1 Gene
- Nucleus.
- Nucleoplasm (4)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000785 | chromatin | IEA | -- |
GO:0005634 | nucleus | IDA,IEA | 9569025 |
GO:0005654 | nucleoplasm | IDA,TAS | -- |
GO:0005681 | spliceosomal complex | IDA,IEA | 15194481 |
GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for SNW1 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Signaling by NOTCH1 | ||
2 | Notch signaling pathway (KEGG) |
.30
|
|
3 | mRNA Splicing - Major Pathway |
.79
|
.50
|
4 | Pre-NOTCH Expression and Processing | ||
5 | Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer |
Pathways by source for SNW1 Gene
1 Sino Biological pathway for SNW1 Gene
3 BioSystems pathways for SNW1 Gene
22 Reactome pathways for SNW1 Gene
4 KEGG pathways for SNW1 Gene
2 GeneGo (Thomson Reuters) pathways for SNW1 Gene
1 R&D Systems pathway for SNW1 Gene
1 Qiagen pathway for SNW1 Gene
Interacting Proteins for SNW1 Gene
SIGNOR curated interactions for SNW1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 14985122 |
GO:0000350 | generation of catalytic spliceosome for second transesterification step | IBA | -- |
GO:0000398 | mRNA splicing, via spliceosome | TAS,IEA | -- |
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
Transcripts for SNW1 Gene
mRNA/cDNA for SNW1 Gene
- (3) REFSEQ mRNAs :
- (17) Additional mRNA sequences :
- (357) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SNW1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for SNW1
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-
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-
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ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||||||||||||
SP2: |
Expression for SNW1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SNW1 Gene
NURSA nuclear receptor signaling pathways regulating expression of SNW1 Gene:
SNW1SOURCE GeneReport for Unigene cluster for SNW1 Gene:
Hs.445498Evidence on tissue expression from TISSUES for SNW1 Gene
- Liver(4.5)
- Nervous system(4.5)
- Lung(2.2)
- Kidney(2)
Primer Products
-
OriGene qPCR primer pairs for SNW1
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNW1 Gene
Orthologs for SNW1 Gene
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | SNW1 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany | |||
SNW1 33 |
|
||||
oppossum (Monodelphis domestica) |
Mammalia | SNW1 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | SNW1 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | SNW1 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Snw1 16 34 33 |
|
||
rat (Rattus norvegicus) |
Mammalia | Snw1 33 |
|
||
chicken (Gallus gallus) |
Aves | SNW1 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | SNW1 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | snw1 33 |
|
||
Str.6904 33 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.28747 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | snw1 33 34 |
|
||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004521 33 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | Bx42 35 33 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | skp-1 33 34 |
|
||
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PRP45 34 36 |
|
OneToOne | |
thale cress (Arabidopsis thaliana) |
eudicotyledons | SKIP 33 |
|
||
rice (Oryza sativa) |
Liliopsida | Os02g0759800 33 |
|
||
Os.19400 33 |
|
||||
barley (Hordeum vulgare) |
Liliopsida | Hv.2879 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2170 34 |
|
OneToOne | |
bread mold (Neurospora crassa) |
Ascomycetes | NCU03799 33 |
|
||
fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | prp45 33 |
|
||
sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4259 33 |
|
- Species where no ortholog for SNW1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SNW1 Gene
Pseudogenes.org Pseudogenes for SNW1 Gene
No data available for Paralogs for SNW1 Gene
Variants for SNW1 Gene
SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000021833 | -- | 77,745,881(-) | G/A | intron_variant | |
rs1000067780 | -- | 77,725,085(-) | C/A | intron_variant | |
rs1000082717 | -- | 77,751,562(-) | T/C | intron_variant | |
rs1000275309 | -- | 77,726,347(-) | T/G | intron_variant | |
rs1000323371 | -- | 77,731,361(-) | A/G | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv1469738 | CNV | insertion | 17803354 |
esv2759998 | CNV | gain | 17122850 |
esv34940 | CNV | gain | 17911159 |
esv3551814 | CNV | deletion | 23714750 |
esv3635010 | CNV | gain | 21293372 |
esv3635013 | CNV | loss | 21293372 |
nsv519957 | CNV | loss | 19592680 |
nsv520021 | CNV | gain | 19592680 |
nsv521287 | CNV | gain | 19592680 |
Additional Variant Information for SNW1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SNW1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNW1 Gene
Disorders for SNW1 Gene
Additional Disease Information for SNW1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for SNW1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNW1 Gene
Publications for SNW1 Gene
- The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein. (PMID: 20368803) Stegmann CM … Wahl MC (PloS one 2010) 3 4 22 58
- A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR. (PMID: 20007319) Wang X … Shi Y (The Journal of biological chemistry 2010) 3 4 22 58
- SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation. (PMID: 19818711) Brès V … Jones KA (Molecular cell 2009) 3 4 22 58
- Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP. (PMID: 16595688) Xu C … Zhang Q (The Journal of biological chemistry 2006) 3 4 22 58
- CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor. (PMID: 16102918) Scott KL … Plon SE (Gene 2005) 3 4 22 58
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- Santa Cruz Biotechnology (SCBT) Antibodies for SNW1
- Search Santa Cruz Biotechnology (SCBT) for SNW1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SNW1
- Custom Antibody ServicesProSci Antibodies for SNW1
- Search for SNW1 Proteins at ProSci
- genomics-online: cdna clones - Search results for 101 available SNW1 gene related products
- Overview of 101 available SNW1 gene related products
- orf clones - Search results for 101 available SNW1 gene related products
- Overview of 101 available SNW1 gene related products
- genomics-online: gRNA clones - Search results for 101 available SNW1 gene related products
- Overview of 101 available SNW1 gene related products
- genomics-online: primer clones - Search results for 101 available SNW1 gene related products
- Overview of 101 available SNW1 gene related products
- genomics-online: shRNA clones - Search results for 101 available SNW1 gene related products
- Overview of 101 available SNW1 gene related products
Sources for SNW1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew