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Aliases for SNTN Gene

Aliases for SNTN Gene

  • Sentan, Cilia Apical Structure Protein 2 3
  • S100A-Like Protein 2 3
  • S100A1L 3 4
  • S100 Calcium-Binding Protein A1-Like 4
  • Protein S100-A1-Like 4
  • S100AL 3
  • Sentan 3

External Ids for SNTN Gene

Summaries for SNTN Gene

GeneCards Summary for SNTN Gene

SNTN (Sentan, Cilia Apical Structure Protein) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding.

UniProtKB/Swiss-Prot for SNTN Gene

  • May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNTN Gene

Genomics for SNTN Gene

Regulatory Elements for SNTN Gene

Genomic Location for SNTN Gene

63,652,668 bp from pter
63,679,020 bp from pter
26,353 bases
Plus strand

Genomic View for SNTN Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for SNTN Gene

Proteins for SNTN Gene

  • Protein details for SNTN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • B7FF65

    Protein attributes for SNTN Gene

    147 amino acids
    Molecular mass:
    16468 Da
    Quaternary structure:
    No Data Available
    • Sentan means tip in Japanese

neXtProt entry for SNTN Gene

Proteomics data for SNTN Gene at MOPED

Post-translational modifications for SNTN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNTN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SNTN Gene

Domains & Families for SNTN Gene

Protein Domains for SNTN Gene


Suggested Antigen Peptide Sequences for SNTN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the S-100 family.
  • Belongs to the S-100 family.
genes like me logo Genes that share domains with SNTN: view

No data available for Gene Families for SNTN Gene

Function for SNTN Gene

Molecular function for SNTN Gene

UniProtKB/Swiss-Prot Function:
May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.

Phenotypes for SNTN Gene

genes like me logo Genes that share phenotypes with SNTN: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for SNTN Gene

Localization for SNTN Gene

Subcellular locations from UniProtKB/Swiss-Prot for SNTN Gene

Cell projection, cilium. Note=Expressed exclusively at the cilium tip where it localizes between the cell membrane and peripheral A-subfibers. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for SNTN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005929 cilium IEA --
genes like me logo Genes that share ontologies with SNTN: view

No data available for Subcellular locations from COMPARTMENTS for SNTN Gene

Pathways & Interactions for SNTN Gene

SuperPathways for SNTN Gene

No Data Available

Interacting Proteins for SNTN Gene

Gene Ontology (GO) - Biological Process for SNTN Gene


No data available for Pathways by source and SIGNOR curated interactions for SNTN Gene

Drugs & Compounds for SNTN Gene

No Compound Related Data Available

Transcripts for SNTN Gene

mRNA/cDNA for SNTN Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(49) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNTN Gene

Sentan, cilia apical structure protein:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNTN

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNTN Gene

No ASD Table

Relevant External Links for SNTN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNTN Gene

mRNA expression in normal human tissues for SNTN Gene

mRNA differential expression in normal tissues according to GTEx for SNTN Gene

This gene is overexpressed in Fallopian Tube (x21.2), Cervix - Endocervix (x16.0), and Lung (x11.6).

SOURCE GeneReport for Unigene cluster for SNTN Gene Hs.130704

genes like me logo Genes that share expression patterns with SNTN: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SNTN Gene

Orthologs for SNTN Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNTN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SNTN 35
  • 85.71 (n)
  • 78.23 (a)
  • 76 (a)
(Canis familiaris)
Mammalia SNTN 35
  • 86.85 (n)
  • 82.31 (a)
  • 82 (a)
(Mus musculus)
Mammalia Sntn 35
  • 82.99 (n)
  • 72.11 (a)
Sntn 16
Sntn 36
  • 72 (a)
(Pan troglodytes)
Mammalia SNTN 35
  • 99.32 (n)
  • 97.96 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Sntn 35
  • 82.05 (n)
  • 68.53 (a)
(Monodelphis domestica)
Mammalia SNTN 36
  • 67 (a)
(Gallus gallus)
Aves SNTN 35
  • 62.73 (n)
  • 57.64 (a)
  • 56 (a)
(Anolis carolinensis)
Reptilia SNTN 36
  • 55 (a)
Species with no ortholog for SNTN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNTN Gene

Gene Tree for SNTN (if available)
Gene Tree for SNTN (if available)

Paralogs for SNTN Gene

(1) SIMAP similar genes for SNTN Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with SNTN: view

No data available for Paralogs for SNTN Gene

Variants for SNTN Gene

Sequence variations from dbSNP and Humsavar for SNTN Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs924067 -- 63,659,018(+) TAATA(C/T)CTGTA intron-variant
rs1039078 -- 63,662,290(+) TGTTG(C/T)GTCCC intron-variant
rs1158143 -- 63,653,948(+) TCATA(C/T)GGTGA intron-variant
rs1158144 -- 63,654,134(+) CCTAG(C/T)AACTG intron-variant
rs1495909 -- 63,654,324(+) AGTCC(A/C)GAGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNTN Gene

Variant ID Type Subtype PubMed ID
esv2422509 CNV Deletion 17116639
nsv834716 CNV Loss 17160897
nsv876886 CNV Gain 21882294
nsv3849 CNV Insertion 18451855
nsv460581 CNV Loss 19166990

Variation tolerance for SNTN Gene

Residual Variation Intolerance Score: 57.21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.15; 39.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SNTN Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNTN Gene

Disorders for SNTN Gene

Relevant External Links for SNTN

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SNTN: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNTN Gene

Publications for SNTN Gene

  1. Sentan: a novel specific component of the apical structure of vertebrate motile cilia. (PMID: 18829862) Kubo A. … Amagai M. (Mol. Biol. Cell 2008) 2 67
  2. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PMID: 17903301) Vasan R.S. … Benjamin E.J. (BMC Med. Genet. 2007) 67
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 67
  4. Transcriptional gene expression profile of human nasopharynx. (PMID: 15289893) Liu X.-Q. … Zeng Y.-X. (Int. J. Mol. Med. 2004) 67

Products for SNTN Gene

Sources for SNTN Gene

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