Aliases for SNTG2 Gene
External Ids for SNTG2 Gene
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNTG2 Gene
SNTG2 (Syntrophin, Gamma 2) is a Protein Coding gene. Diseases associated with SNTG2 include duchenne muscular dystrophy. GO annotations related to this gene include phospholipid binding and PDZ domain binding. An important paralog of this gene is SNTG1.
UniProtKB/Swiss-Prot for SNTG2 Gene
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity).