Aliases for SNTG2 Gene
External Ids for SNTG2 Gene
Previous GeneCards Identifiers for SNTG2 Gene
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNTG2 Gene
SNTG2 (Syntrophin Gamma 2) is a Protein Coding gene. GO annotations related to this gene include actin binding and PDZ domain binding. An important paralog of this gene is SNTG1.
UniProtKB/Swiss-Prot for SNTG2 Gene
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity).