Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNRPF Gene

protein-coding   GIFtS: 57
GCID: GC12P096252

small nuclear ribonucleoprotein polypeptide F

 Explore 4 diseases affiliated with
SNRPF via our new
 Human Malady Compendium 
Biological research products
for SNRPF
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Small Nuclear Ribonucleoprotein Polypeptide F1 2     SMF2
Sm-F1 2 3     Small Nuclear Ribonucleoprotein F2
Sm Protein F2 3     PBSCF3
SnRNP-F1     SmF3

External Ids:    HGNC: 111621   Entrez Gene: 66362   Ensembl: ENSG000001393437   OMIM: 6035415   UniProtKB: P623063   

Export aliases for SNRPF gene to outside databases

Previous GC identifers: GC12P095685 GC12P096616 GC12P096185 GC12P094755 GC12P094776 GC12P093317


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RUXF_HUMAN, P62306
Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with
snRNP U1, U2, U4/U6 and U5

Gene Wiki entry for SNRPF (Small nuclear ribonucleoprotein polypeptide F)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNRPF gene promoter:
         Brachyury   Tal-1beta   CBF-C   E47   N-Myc   CBF-A   CBF-B   CP1C   CP1A   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNRPF promoter sequence
   Search SABiosciences Chromatin IP Primers for SNRPF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNRPF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q23.1   Ensembl cytogenetic band:  12q23.1   HGNC cytogenetic band: 12q23.1

SNRPF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNRPF gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P096252:  view genomic region     (about GC identifiers)

Start:
96,252,706 bp from pter      End:
96,297,606 bp from pter
Size:
44,901 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RUXF_HUMAN, P62306 (See protein sequence)
Recommended Name: Small nuclear ribonucleoprotein F  
Size: 86 amino acids; 9725 Da
Subunit: Component of the heptameric ring U7 snRNP complex, or U7 Sm protein core complex, at least composed of LSM10,
LSM11, SNRPB, SNRPD3, SNRPE, SNRPF, SNRPG and U7 snRNA. Formation of the U7 snRNP is an ATP-dependent process mediated
by a specialized SMN complex containing at least the Sm protein core complex and additionally, the U7-specific LSM10
and LSM11 proteins. Identified in the spliceosome C complex. Component of the U11/U12 snRNPs that are part of the
U12-type spliceosome
Subcellular location: Nucleus
6/7 PDB 3D structures from and Proteopedia for SNRPF (see all 7):
2Y9A (3D)        2Y9B (3D)        2Y9C (3D)        2Y9D (3D)        3CW1 (3D)        3PGW (3D)    
Secondary accessions: A2VCR2 B2R498 Q15356 Q6IBQ1 Q6P4I0

Explore the universe of human proteins at neXtProt for SNRPF: NX_P62306

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P62306

  • SNRPF Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003086.1  
    ENSEMBL proteins: 
     ENSP00000266735   ENSP00000447751   ENSP00000447127  
    Reactome Protein details: P62306
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: SNRPF
    OriGene Protein Over-expression Lysate: SNRPF
    OriGene Custom Protein Services for SNRPF 
    GenScript Custom Purified and Recombinant Proteins Services for SNRPF
    Novus Biologicals SNRPF Proteins
    Novus Biologicals SNRPF Lysate
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for SNRPF
    Uscn Proteins for SNRPF

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0005681spliceosomal complex IDA7744013
    GO:0005683U7 snRNP IDA11574479
    GO:0005689U12-type spliceosomal complex IDA15146077
    GO:0005829cytosol TAS--


    SNRPF for ontologies           About GeneDecksing



    SNRPF Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SNRPF 
    GenScript Custom Superior Antibodies Services for SNRPF
    Novus Biologicals SNRPF Antibodies
    Abcam antibodies for SNRPF 
    Uscn Antibodies for SNRPF
    ThermoFisher Antibodies for SNRPF

    Assay Products for SNRPF: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SNRPF
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for SNRPF


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SNRPF for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001163 Ribonucl_LSM
     IPR016487 snRNP_SmF
     IPR006649 Ribonucl_LSM_euk/arc
     IPR010920 LSM_dom

    Graphical View of Domain Structure for InterPro Entry P62306

    ProtoNet protein and cluster: P62306

    1 Blocks protein family: IPB010920 Like-Sm ribonucleoprotein-related

    UniProtKB/Swiss-Prot: RUXF_HUMAN, P62306
    Similarity: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RUXF_HUMAN, P62306
    Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with
    snRNP U1, U2, U4/U6 and U5

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: SNRPF
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNRPF
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate SNRPF:
    hsa-miR-3163 hsa-miR-495 hsa-miR-7-1* hsa-miR-7-2* hsa-miR-410
    SwitchGear 3'UTR luciferase reporter plasmidSNRPF 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNRPF (see all 4)
    OriGene shRNA RFP: SNRPF
    OriGene siRNA: SNRPF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNRPF

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SNRPF

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPF (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPF (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SNRPF (NM_003095)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNRPF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRPF 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SNRPF
    Search LifeMap BioReagents cell lines for SNRPF

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNRPF

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IMP7744013


    SNRPF for ontologies           About GeneDecksing


    8 GenomeRNAi human phenotypes for SNRPF:
     Cell cycle / mitosis defect  Cell division defect  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 
     Decreased viability of wild-ty  Increased G2M DNA content  Increased number of mitotic ce  Synthetic lethal with c-Myc af 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1mRNA Splicing - Major Pathway
    mRNA Splicing1.00
    mRNA processing0.48
    mRNA Splicing - Major Pathway1.00
    mRNA Splicing - Minor Pathway0.40
    Processing of Capped Intron-Containing Pre-mRNA0.96
    Spliceosome0.31
    mRNA Processing0.82
    2SLBP independent Processing of Histone Pre-mRNAs
    SLBP independent Processing of Histone Pre-mRNAs1.00
    snRNP Assembly0.28
    SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs0.91
    Metabolism of non-coding RNA0.28
    3RNA Polymerase II Transcription Termination
    RNA Polymerase II Transcription Termination1.00
    Cleavage of Growing Transcript in the Termination Region 1.00
    Post-Elongation Processing of the Transcript1.00
    4Transcription
    Transcription1.00
    RNA Polymerase II Transcription0.69
    5Post-Elongation Processing of Intronless pre-mRNA
    Processing of Capped Intronless Pre-mRNA1.00
    Post-Elongation Processing of Intronless pre-mRNA1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for SNRPF 
        mRNA processing

    5/18        Reactome Pathways for SNRPF (see all 18)
        mRNA Splicing
    RNA Polymerase II Transcription
    snRNP Assembly
    Cleavage of Growing Transcript in the Termination Region
    Metabolism of non-coding RNA


    1         Kegg Pathway  (Kegg details for SNRPF):
        Spliceosome


    SNRPF for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNRPF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/177 Interacting proteins for SNRPF (P623062, 3 ENSP000002667354) via UniProtKB, MINT, STRING, and/or I2D (see all 177)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNRPD2P623162, 3, ENSP000003423744MINT-49763 MINT-8332690 I2D: score=12 STRING: ENSP00000342374
    SNRPEP623042, 3, ENSP000004005914MINT-49760 MINT-8332778 I2D: score=11 STRING: ENSP00000400591
    SF3A2Q154282, 3, ENSP000002214944MINT-5205359 I2D: score=2 STRING: ENSP00000221494
    SNRPGP623082, 3, ENSP000002723484MINT-8332789 I2D: score=2 STRING: ENSP00000272348
    MAP3K1Q132332, 3MINT-48357 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000387spliceosomal snRNP assembly TAS--
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006366transcription from RNA polymerase II promoter TAS--
    GO:0006369termination of RNA polymerase II transcription TAS--
    GO:0006397mRNA processing TAS--


    SNRPF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNRPF
    Search CenterWatch for drugs/clinical trials and news about SNRPF / RUXF 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SNRPF gene: 
    NM_003095.2  

    Unigene Cluster for SNRPF:

    Small nuclear ribonucleoprotein polypeptide F
    Hs.105465  [show with all ESTs]
    Unigene Representative Sequence: CD388516
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000266735(uc001tej.3) ENST00000551316 ENST00000553192 ENST00000552085
    ENST00000549580

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: SNRPF
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNRPF
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate SNRPF:
    hsa-miR-3163 hsa-miR-495 hsa-miR-7-1* hsa-miR-7-2* hsa-miR-410
    SwitchGear 3'UTR luciferase reporter plasmidSNRPF 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNRPF (see all 4)
    OriGene shRNA RFP: SNRPF
    OriGene siRNA: SNRPF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNRPF
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPF (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPF (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SNRPF (NM_003095)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNRPF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRPF 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNRPF
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNRPF
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNRPF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRPF

    Additional cDNA sequence: 

    AK311752.1 BC002505.2 BC063397.1 BC128452.1 BC128453.1 CR456751.1 X85372.1 

    8 DOTS entries:

    DT.100668416  DT.92442627  DT.121211444  DT.92442631  DT.99996090  DT.100685752  DT.100842550  DT.95347974 

    24/225 AceView cDNA sequences (see all 225):

    AA668189 BQ647431 AV703743 BQ882115 AI347053 BC002505 AW327351 BM701732 
    BU931026 AI274390 AA612722 CB998801 BQ647236 AW873105 BM712034 BE269077 
    BG283561 AI199012 BE408562 AW327621 BM554302 AA524133 BQ648155 BM423489 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNRPF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGCTTGCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SNRPF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNRPF

    SOURCE GeneReport for Unigene cluster: Hs.105465
        SABiosciences Custom PCR Arrays for SNRPF
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNRPF
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNRPF
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNRPF
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRPF
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNRPF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SNRPF gene from 8/38 species (see all 38)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SNRPF1 small nuclear ribonucleoprotein polypeptide F 84.11(n)
    100(a)
      417916  XM_416157.3  XP_416157.2 
    lizard
    (Anolis carolinensis)
    Reptilia SNRPF6
    --
    97(a)
    1 ↔ 1
    5(30641445-30643258)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC056127.12   -- 84.53(n)    BC056127.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BQ076957.12   -- 82.64(n)    BQ076957.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta DebB3
    SmF1
    mRNA splicing3
    Small ribonucleoprotein particle protein SmF1
    79(a)3
    71.83(n)1
    78.57(a)1
      48E63
    363141  NM_078984.31  NP_523708.21 
    worm
    (Caenorhabditis elegans)
    Secernentea snr-51 Protein SNR-5 65.37(n)
    72.73(a)
      176103  NM_066307.3  NP_498708.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RUXF1 small nuclear ribonucleoprotein F 70.04(n)
    77.22(a)
      829145  NM_119168.3  NP_194751.1 
    rice
    (Oryza sativa)
    Liliopsida AK062752.12   -- 72.48(n)    AK062752.1 


    ENSEMBL Gene Tree for SNRPF (if available)
    TreeFam Gene Tree for SNRPF (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNRPF gene
    18/82 SIMAP similar genes for SNRPF using alignment to 2 protein entries:     RUXF_HUMAN (see all proteins) (see all similar genes):
    FBLN5    ARL6IP5    NDC80    C3orf33    MYL10    ASCC1
    HEXDC    MKRN1    MRPL45    SEC14L3    ZNF415    COQ5
    NLRC5    pp12301    ANKRD55    EIF3G    GNB2L1    TP63

    SNRPF for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for SNRPF (see all 6)
    PGOHUM00000248429 PGOHUM00000246843 PGOHUM00000246857 PGOHUM00000244640 PGOHUM00000247558


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/142 NCBI SNPs in SNRPF are shown (see all 142    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1857941071,2
    --96250745(+) GGCTGC/TAGTAA 1 -- us2k10--------
    rs801563121,2
    C,F,--96250818(+) AAAAAA/TATTTA 1 -- us2k11Minor allele frequency- T:0.19NA 120
    rs786888991,2
    --96250838(+) GAAAAA/TCCAAC 1 -- us2k10--------
    rs1896534261,2
    --96250906(+) GAGAAA/TACAGC 1 -- us2k10--------
    rs79701331,2
    C,F,A,H,--96250933(+) TAAAAC/TACATA 1 -- us2k132Minor allele frequency- T:0.30NS EA NA WA 3402
    rs1823271691,2
    --96251057(+) TAGGGC/TCCATC 1 -- us2k10--------
    rs1887260561,2
    --96251259(+) CCAGGC/TGGTGC 1 -- us2k10--------
    rs1408250101,2
    --96251278(+) TAGAGC/TGTACT 1 -- us2k10--------
    rs557081881,2
    C,--96251472(+) CACGAT/CTGTTG 1 -- us2k12Minor allele frequency- C:0.05WA 120
    rs37640361,2
    C,F,A,H,--96251493(-) CTACTA/GTGTGT 1 -- us2k126Minor allele frequency- G:0.21EA NS NA WA CSA 4247

    HapMap Linkage Disequilibrium report for SNRPF (96252706 - 96297606 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SNRPF: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNRPF
    DNA2.0 Custom Variant and Variant Library Synthesis for SNRPF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SNRPF for disorders           About GeneDecksing

    OMIM gene information: 603541    OMIM disorders: --

    4 diseases for SNRPF:    About MalaCards
    spinal muscular atrophy    muscular atrophy    malaria    neuronitis


    Export disorders for SNRPF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNRPF gene, integrated from 9 sources (see all 49):
    (articles sorted by number of sources associating them with SNRPF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions. (PubMed id 7744013)1, 2, 3 Hermann H....Luehrmann R. (1995)
    2. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PubMed id 15146077)1, 2 Will C.L.... Luehrmann R. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    5. Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. (PubMed id 11574479)1, 2 Pillai R.S.... Mueller B. (2001)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PubMed id 21319273)1 Neganova I....Lako M. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6636 HGNC: 11162 AceView: SNRPF Ensembl:ENSG00000139343 euGenes: HUgn6636
    ECgene: SNRPF Kegg: 6636 H-InvDB: SNRPF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNRPF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SNRPF gene:
    Search GeneIP for patents involving SNRPF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for SNRPF  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNRPF   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNRPF  
     OriGene Protein Over-expression Lysate for SNRPF   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for SNRPF   OriGene 3'-UTR Clone for SNRPF  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPF   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPF  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for SNRPF   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SNRPF   OriGene Custom Protein Services for SNRPF  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNRPF
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNRPF
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNRPF
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNRPF
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRPF
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNRPF
     GenScript Custom Purified and Recombinant Proteins Services for SNRPF GenScript cDNA clones with any tag delivered in your preferred vector for SNRPF
     GenScript Custom Assay Services for SNRPF GenScript Custom Superior Antibodies Services for SNRPF
     GenScript Custom overexpressing Cell Line Services for SNRPF CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SNRPF promoter
     Search Chromatin IP Primers for SNRPF
     RT2 qPCR Primer Assay in human, mouse, rat SNRPF
     Search GNC Networks for SNRPF
     SABiosciences Custom PCR Arrays for SNRPF
     Search Tocris compounds for SNRPF
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SNRPF antibodies
     SNRPF proteins
     SNRPF lysates
     Antibodies for SNRPF
     See all of Abcam's Antibodies, Kits and Proteins for SNRPF
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for SNRPF




     SNRPF Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for SNRPF
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNRPF
     SwitchGear 3'UTR luciferase reporter plasmids for SNRPF
     SwitchGear Promoter luciferase reporter plasmids for SNRPF
     ThermoFisher Antibodies for SNRPF
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRPF
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SNRPF gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4