Aliases for SNRPE Gene
External Ids for SNRPE Gene
Previous GeneCards Identifiers for SNRPE Gene
GeneCards Summary for SNRPE Gene
SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E) is a Protein Coding gene. Diseases associated with SNRPE include hypotrichosis 11 and rubeosis iridis. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. GO annotations related to this gene include RNA binding.
UniProtKB/Swiss-Prot for SNRPE Gene
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3-end processing. May indirectly play a role in hair development.