Aliases for SNRPD3 Gene
External Ids for SNRPD3 Gene
Previous GeneCards Identifiers for SNRPD3 Gene
This gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for SNRPD3 Gene
SNRPD3 (Small Nuclear Ribonucleoprotein D3 Polypeptide) is a Protein Coding gene. Diseases associated with SNRPD3 include Lupus Erythematosus and Systemic Lupus Erythematosus. Among its related pathways are mRNA Splicing - Major Pathway and Processing of Capped Intronless Pre-mRNA. GO annotations related to this gene include poly(A) RNA binding and histone pre-mRNA DCP binding.
UniProtKB/Swiss-Prot for SNRPD3 Gene
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3-end processing.