SNRPB Gene
protein-coding GIFtS: 59
GCID: GC20M002442
|
|
small nuclear ribonucleoprotein polypeptides B and B1
(Previous symbol: SNRPB1)
| |
Aliases
for SNRPB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Small Nuclear Ribonucleoprotein Polypeptides B And B11 2 | | Sm Protein B/B'2 3 | | COD1 2 3 | | B Polypeptide Of Sm Protein2 | | SNRPB11 2 3 | | Sm-B/Sm-B'1 | | Sm-B/B'1 2 3 | | Small Nuclear Ribonucleoprotein Polypeptide B2 | | SnRNP-B1 | | Small Nuclear Ribonucleoprotein Polypeptides B And B'2 | | SmB/SmB'1 2 | | Small Nuclear Ribonucleoprotein-Associated Proteins B And B'2 | | SmB/B'2 3 | | |
Export aliases for SNRPB gene to outside databasesPrevious GC identifers: GC20M002430 GC20M002390 GC20M002437 GC20M002392 |
Summaries
for SNRPB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SNRPB:
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, andU5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded proteinmay also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupuserythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding differentisoforms (B and B') have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RSMB_HUMAN, P14678Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated withsnRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to thedownstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner (By similarity)
Gene Wiki entry for SNRPB
|
Genomic Views
for SNRPB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SNRPB gene promoter:
COUP-TF1 SRF COUP-TF SRF (504 AA) COUP
Other transcription factors
Search SABiosciences Chromatin IP Primers for SNRPB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNRPB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13SNRPB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M002442: view genomic region
(about GC identifiers)
Start:
|
2,442,280 bp from pter |
End:
|
2,451,499 bp from pter |
Size:
|
9,220 bases |
Orientation:
|
minus strand |
|
Proteins
for SNRPB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RSMB_HUMAN, P14678 (See
protein sequence)Recommended Name: Small nuclear ribonucleoprotein-associated proteins B and B' Size: 240 amino acids; 24610 Da
Subunit: Identified in a histone pre-mRNA complex, at least composed of ERI1, LSM11, SLBP, SNRPB, SYNCRIP and YBX1 (Bysimilarity). Component of the heptameric ring U7 snRNP complex, or U7 Sm protein core complex, at least composed ofLSM10, LSM11, SNRPB, SNRPD3, SNRPE, SNRPF, SNRPG and U7 snRNA. Formation of the U7 snRNP is an ATP-dependent processmediated by a specialized SMN complex containing at least the Sm protein core complex and additionally, theU7-specific LSM10 and LSM11 proteins. Identified in the spliceosome C complex. Component of the U11/U12 snRNPs thatare part of the U12-type spliceosome. Interacts with CLNS1A, DDX20, LSM11, TDRD3, SNUPN and SMN1
Subcellular location: Nucleus
Miscellaneous: Patients with the autoimmune disease systemic lupus erythematosus (SLE) have autoantibodies directedagainst some of the individual snRNP polypeptides. The most common autoantigen is called Sm. B/b' bear Sm epitopes
Sequence caution: Sequence=AAD54488.1; Type=Erroneous gene model prediction;
6/7 PDB 3D structures from  and Proteopedia  for SNRPB (see all 7):1D3B (3D)
2Y9A (3D)
2Y9B (3D)
2Y9C (3D)
2Y9D (3D)
3CW1 (3D)
Secondary accessions: Q15490 Q6IB35 Q9UIS5Alternative splicing: 3 isoforms: P14678-1 P14678-2 P14678-3 Explore the universe of human proteins at neXtProt for SNRPB: NX_P14678
Post-translational modifications:
Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P14678
SNRPB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_003082.1 NP_937859.1
ENSEMBL proteins: ENSP00000370746 ENSP00000412566 ENSP00000342305 Reactome Protein details: P14678
Human Recombinant Protein Products for SNRPB:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
SNRPB for ontologies About GeneDecksing
SNRPB Antibody Products:
Assay Products for SNRPB: |
Protein
Domains /
Families
for SNRPB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SNRPB for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P14678ProtoNet protein and cluster: P14678 2 Blocks protein families: IPB001163 Small nuclear ribonucleoprotein (Sm protein) IPB010920 Like-Sm ribonucleoprotein-related
UniProtKB/Swiss-Prot: RSMB_HUMAN, P14678Similarity: Belongs to the snRNP SmB/SmN family |
Function
for SNRPB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RSMB_HUMAN, P14678Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated withsnRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to thedownstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner (By similarity) Genatlas biochemistry entry for SNRPB:small nuclear ribonucleoprotein,polypeptides B and B1
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SNRPB for ontologies About GeneDecksing
Phenotypes:
7 GenomeRNAi human phenotypes for SNRPB:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPB (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPB (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SNRPB (NM_003091) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNRPB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRPB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNRPB |
|
Pathways & Interactions
for SNRPB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA Splicing - Major Pathway | | | 2 | SLBP independent Processing of Histone Pre-mRNAs | | | 3 | RNA Polymerase II Transcription Termination | | | 4 | Transcription | | | 5 | Post-Elongation Processing of Intronless pre-mRNA | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SNRPB
5/18 
Reactome Pathways for SNRPB (see all 18)
2 
Kegg Pathways (Kegg details for SNRPB):
SNRPB for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNRPB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/120 Interacting proteins for SNRPB (P146781, 2, 3 ENSP000004125664) via UniProtKB, MINT, STRING, and/or I2D (see all 120)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| CD2BP2 | O954002, 3, ENSP000003049034 | MINT-62827 MINT-62831 MINT-62664 MINT-62853 MINT-62655 MINT-62851 MINT-62852 MINT-62850 MINT-62849 MINT-62833 MINT-62652 I2D:
score=2 STRING: ENSP00000304903 | | SMN1 | Q166372, 3, ENSP000003700834 | MINT-14172 MINT-14173 MINT-14174 I2D:
score=6 STRING: ENSP00000370083 | | GIGYF2 | Q6Y7W62, 3, ENSP000003871704 | MINT-65887 MINT-65884 MINT-65888 MINT-65907 I2D:
score=2 STRING: ENSP00000387170 | | GEMIN4 | P576782, 3, ENSP000003217064 | MINT-15055 MINT-15056 I2D:
score=5 STRING: ENSP00000321706 | | COIL | P384322, 3, ENSP000002403164 | MINT-8052983 I2D:
score=4 STRING: ENSP00000240316 |
About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000387 | spliceosomal snRNP assembly |
TAS | -- | | GO:0000398 | mRNA splicing, via spliceosome |
TAS | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006369 | termination of RNA polymerase II transcription |
TAS | -- | | GO:0006397 | mRNA processing |
TAS | -- |
SNRPB for ontologies About GeneDecksing
|
Drugs & Compounds
for SNRPB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SNRPB
Search CenterWatch for drugs/clinical trials and news about SNRPB / RSMB
|
Transcripts
for SNRPB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SNRPB gene (2 alternative transcripts): NM_003091.3 NM_198216.1 Unigene Cluster for SNRPB: Small nuclear ribonucleoprotein polypeptides B and B1 Hs.83753 [show with all ESTs]Unigene Representative Sequence: BM5640704 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000381342(uc002wga.1) ENST00000438552(uc002wfz.1) ENST00000474384
ENST00000339610(uc010zpv.2 uc002wgb.3 uc010gan.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPB (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPB (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SNRPB (NM_003091) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNRPB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRPB |
Additional cDNA sequence: AK301034.1 AK301206.1 AK307093.1 AK307266.1 AK312620.1 AY742712.1 BC080516.1 CR456969.1 J04564.1 M34081.1 M34082.1 X15893.1 X17567.1 X17568.1 24/27 DOTS entries (see all 27): DT.100045354 DT.455957 DT.101985257 DT.100042501 DT.95325267 DT.99981347 DT.100880258 DT.95099492 DT.100880254 DT.95325250 DT.100880270 DT.102837046 DT.95325254 DT.100880269 DT.120829112 DT.100880264 DT.97862682 DT.100880257 DT.450384 DT.95325273 DT.95325431 DT.100880260 DT.120829127 DT.120829147 24/1609 AceView cDNA sequences (see all 1609): CB145806 CA420343 BF795528 BQ953405 BE734349 CR609487 BG491778 BQ649262 AL555129 BM973199 BI913390 BE261371 BE300018 BM811059 BM423463 BU157536 BE791198 BQ652994 AA315958 BM766212 CR619703 BG758022 CB148949 AW583222
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for SNRPB (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SNRPB
|
Expression
for SNRPB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SNRPB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGATTGTCTG
About this image
See SNRPB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SNRPB
SOURCE GeneReport for Unigene cluster: Hs.83753
SABiosciences Custom PCR Arrays for SNRPB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNRPB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNRPB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNRPB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRPB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNRPB |
Orthologs
for SNRPB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SNRPB gene from 9/28 species (see all 28) About this table
ENSEMBL Gene Tree for SNRPB (if available)
TreeFam Gene Tree for SNRPB (if available) |
Paralogs
for SNRPB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SNRPB gene
- SNRPN2
3 SIMAP similar genes for SNRPB using alignment to 6 protein entries: RSMB_HUMAN (see all proteins):SNRPN NAA38 LSM8
SNRPB for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SNRPB
PGOHUM00000246309
|
Genomic Variants
for SNRPB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SNRPB (2442280 - 2451499 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SNRPB
2 CNVs: 90442 4091 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNRPB |
|
Disorders
/ Diseases
for SNRPB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SNRPB for disorders About GeneDecksing
OMIM gene information: 182282
OMIM disorders: --
10  diseases for SNRPB: About MalaCardssystemic lupus erythematosus lupus erythematosus spinal muscular atrophy muscular atrophy
mutism celiac disease breast cancer malaria
neuronitis herpes simplex
Human Genome Epidemiology (HuGE) Navigator: SNRPB (1 document)
Export disorders for SNRPB gene to outside databases
|
Publications
for SNRPB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SNRPB gene, integrated from 9 sources (see all 89):
(articles sorted by number of sources associating them with SNRPB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes. (PubMed id 16087681)1, 2 Azzouz T.N.... Schuemperli D. (2005)
- The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PubMed id 15146077)1, 2 Will C.L.... Luehrmann R. (2004)
- Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. (PubMed id 12975319)1, 2 Pillai R.S.... Schuemperli D. (2003)
- Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
- SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta. (PubMed id 12095920)1, 2 Narayanan U.... Matera A.G. (2002)
- Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. (PubMed id 11574479)1, 2 Pillai R.S.... Mueller B. (2001)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci. (PubMed id 10556313)1, 2 Gray T.A.... Nicholls R.D. (1999)
- Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. (PubMed id 10025403)1, 2 Kambach C.... Nagai K. (1999)
- The murine gene encoding the highly conserved Sm B protein contains a nonfunctional alternative 3' splice site. (PubMed id 1376292)1, 3 Griffith A.J....Craft J. (1992)
|
External Searches for SNRPB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SNRPB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SNRPB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SNRPB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SNRPB | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SNRPB gene:
Search GeneIP for patents involving SNRPB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SNRPB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SNRPB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNRPB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNRPB | | | OriGene Protein Over-expression Lysate for SNRPB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SNRPB | | OriGene 3'-UTR Clone for SNRPB | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNRPB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SNRPB | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SNRPB | | OriGene Custom Protein Services for SNRPB | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNRPB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNRPB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNRPB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNRPB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRPB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNRPB |
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| | | | Search Tocris compounds for SNRPB |
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 | | | SNRPB Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNRPB |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SNRPB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRPB |
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