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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNRNP40 Gene

protein-coding   GIFtS: 51
GCID: GC01M031732

small nuclear ribonucleoprotein 40kDa (U5)

(Previous name: WD repeat domain 57 (U5 snRNP specific) )
(Previous symbol: WDR57)
 Explore 5 diseases affiliated with
SNRNP40 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SNRNP40    

Aliases
for SNRNP40 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Small Nuclear Ribonucleoprotein 40kDa (U5)1 2     U5 SnRNP 40 KDa Protein2 3
PRP8BP1 2 3     WD Repeat-Containing Protein 572 3
WDR571 2 3     40K2
PRPF8BP1 2 5     RP11-490K7.32
SPF381 2 5     U5 Small Nuclear Ribonucleoprotein 40 KDa Protein2
HPRP8BP1 2     U5 SnRNP-Specific 40 KDa Protein (HPrp8-Binding)2
WD Repeat Domain 57 (U5 SnRNP Specific)1 2     U5-40kD Protein2
38 KDa-Splicing Factor2 3     SFP383
U5-40K2 3     HPRP8BP1 2
Prp8-Binding Protein2 3     U5 SnRNP-Specific 40 KDa Protein3

External Ids:    HGNC: 308571   Entrez Gene: 94102   Ensembl: ENSG000000606887   OMIM: 6077975   UniProtKB: Q96DI73   

Export aliases for SNRNP40 gene to outside databases

Previous GC identifers: GC01M031506 GC01M029838


Summaries
for SNRNP40 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SNRNP40:
This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the
spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7
Function: Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome,
a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs

Gene Wiki entry for SNRNP40 (WDR57)


Genomic Views
for SNRNP40 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNRNP40 gene promoter:
         Pax-6   POU3F2   RORalpha2   NF-AT   AREB6   NF-AT4   NF-AT2   HOXA5   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SNRNP40 promoter sequence
   Search SABiosciences Chromatin IP Primers for SNRNP40

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNRNP40


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.2   Ensembl cytogenetic band:  1p35.2   HGNC cytogenetic band: 1p35.2

SNRNP40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNRNP40 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M031732:  view genomic region     (about GC identifiers)

Start:
 31,732,415 bp from pter      End:
 31,769,662 bp from pter
Size:
 37,248 bases      Orientation:
 minus strand

Proteins
for SNRNP40 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7 (See protein sequence)
Recommended Name: U5 small nuclear ribonucleoprotein 40 kDa protein  
Size: 357 amino acids; 39311 Da
Subunit: Identified in the spliceosome C complex. Part of the U5 snRNP complex. Interacts with PRPF8. Component of the
U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31,
SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, NHP2L1, EFTUD2, SART1 and USP39
Subcellular location: Nucleus
Sequence caution: Sequence=AAC64084.1; Type=Frameshift; Positions=319; Note=An insertion/deletion of a short nucleotide
stretch in its cDNA resulting in a frameshift;
Secondary accessions: O75938 O95320

Explore the universe of human proteins at neXtProt for SNRNP40: NX_Q96DI7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96DI7

    • SNRNP40 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004805.2  
    ENSEMBL proteins: 
     ENSP00000263694   ENSP00000362825   ENSP00000406841  
    Reactome Protein details: Q96DI7
    Human Recombinant Protein Products: 
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    Novus Biologicals SNRNP40 Proteins
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SNRNP40

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005682U5 snRNP TAS9774689
    GO:0005730NOT nucleolus IDA--
    GO:0005732small nucleolar ribonucleoprotein complex NAS9774689


    SNRNP40 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SNRNP40

    Protein Domains /
    Families
    for SNRNP40 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SNRNP40 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96DI7

    ProtoNet protein and cluster: Q96DI7

    UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7
    Similarity: Contains 7 WD repeats


    Function
    for SNRNP40 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7
    Function: Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome,
    a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs

    miRNA
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    hsa-miR-300 hsa-miR-487a hsa-miR-381 hsa-miR-575 hsa-miR-138-2* hsa-miR-154* hsa-miR-374c hsa-miR-655
    SwitchGear 3'UTR luciferase reporter plasmid: SNRNP40 3' UTR sequence
    Inhib. RNA
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    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SNRNP40

    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNRNP40 

    Cell Line
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    Search LifeMap BioReagents cell lines for SNRNP40

    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI9774689


    SNRNP40 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SNRNP40 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1mRNA Splicing - Major Pathway
    		mRNA Splicing1.00
    		mRNA processing0.48
    		mRNA Splicing - Major Pathway1.00
    		mRNA Splicing - Minor Pathway0.40
    		Processing of Capped Intron-Containing Pre-mRNA0.96
    		Spliceosome0.31
    		mRNA Processing0.82
    2Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for SNRNP40 
        mRNA processing

    5/6        Reactome Pathways for SNRNP40 (see all 6)
        mRNA Splicing - Major Pathway
    mRNA Splicing
    Gene Expression
    mRNA Processing
    mRNA Splicing - Minor Pathway


    1         Kegg Pathway  (Kegg details for SNRNP40):
        Spliceosome


    SNRNP40 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNRNP40

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/800 Interacting proteins for SNRNP40 (Q96DI71, 2, 3 ENSP000002636944) via UniProtKB, MINT, STRING, and/or I2D (see all 800)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRPF8Q6P2Q91, 2, 3, ENSP000003043504EBI-538492,EBI-538479 MINT-7945693 MINT-7947479 I2D: score=3 STRING: ENSP00000304350
    PRPF6O949062, 3, ENSP000002660794MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000266079
    SF3B1O755332, 3, ENSP000003353214MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000335321
    SNRNP200O756432, 3, ENSP000003171234MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000317123
    SRRM1Q8IYB32, 3, ENSP000003262614MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000326261
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000375RNA splicing, via transesterification reactions TAS9774689
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006396RNA processing TAS9774689
    GO:0008380RNA splicing TAS--
    GO:0010467gene expression TAS--


    SNRNP40 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SNRNP40 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNRNP40
    Search CenterWatch for drugs/clinical trials and news about SNRNP40 / SNR40 

    Transcripts
    for SNRNP40 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SNRNP40 gene: 
    NM_004814.2  

    Unigene Cluster for SNRNP40:

    Small nuclear ribonucleoprotein 40kDa (U5)
    Hs.33962  [show with all ESTs]
    Unigene Representative Sequence: NM_004814
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263694(uc001bso.3 uc010oge.2) ENST00000486941 ENST00000489853
    ENST00000373720(uc009vtt.3) ENST00000491106 ENST00000474025 ENST00000463988
    ENST00000446633

    miRNA
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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate SNRNP40 (see all 10):
    hsa-miR-300 hsa-miR-487a hsa-miR-381 hsa-miR-575 hsa-miR-138-2* hsa-miR-154* hsa-miR-374c hsa-miR-655
    SwitchGear 3'UTR luciferase reporter plasmid: SNRNP40 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNRNP40 (see all 4)
    OriGene shRNA RFP: SNRNP40
    OriGene siRNA: SNRNP40
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNRNP40
    Clone
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    GenScript: all cDNA clones in your preferred vector: SNRNP40 (NM_004814)
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    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNRNP40
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRNP40

    Additional cDNA sequence: 

    AF090988.1 AK074516.1 AK298823.1 AK313800.1 BC001494.2 EF011621.1 

    10 DOTS entries:

    DT.208442  DT.91670632  DT.406654  DT.40230280  DT.95171446  DT.97807534  DT.100772918  DT.100783714 
    DT.120847331  DT.91855778 

    24/184 AceView cDNA sequences (see all 184):

    BM562019 CR611220 CR624677 BQ056159 BQ065130 CR622464 BQ057287 BQ677340 
    BU167893 AK074516 CR605147 AI678399 BM905254 CR610792 BI819498 CR609455 
    BQ054462 BM679119 BM474760 BM906279 CR590081 BI917826 CB152868 CR602112 

    GeneLoc Exon Structure


    Expression
    for SNRNP40 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNRNP40 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGGCTCCAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SNRNP40 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNRNP40

    SOURCE GeneReport for Unigene cluster: Hs.33962
        SABiosciences Custom PCR Arrays for SNRNP40
    Primer
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    In Situ
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    Orthologs
    for SNRNP40 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SNRNP40 gene from 8/33 species (see all 33)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SNRNP401 small nuclear ribonucleoprotein 40kDa (U5) 79.44(n)
    92.8(a)    		   419556  NM_001006308.1  NP_001006308.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SNRNP406
    		 --
    		 85(a)
    		 1 ↔ 1
    		 GL343563.1(155788-162339)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BC045034.12   -- 80.97(n)    BC045034.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc563122 similar to U5 snRNP-specific 40 kDa protein (hPrp8-binding) 77.62(n)   393292  BC051783.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG34361 CG3436 59.55(n)
    61.46(a)    		   33180  NM_134657.2  NP_608501.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea F08G12.21 Protein F08G12.2 58.18(n)
    56.21(a)    		   181319  NM_077485.4  NP_509886.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G437701 Prp8 binding protein 60.65(n)
    59.94(a)    		   818980  NM_129939.5  NP_181905.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.47362 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 75.28(n)    AK111971.1 


    ENSEMBL Gene Tree for SNRNP40 (if available)
    TreeFam Gene Tree for SNRNP40 (if available) 

    Paralogs
    for SNRNP40 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNRNP40 gene
    POC1B2  WDR832  WDR52  ATG16L12  WDR882  WDR5B2  KATNB12  PAFAH1B12  
    PRPF42  DAW12  WDR382  ATG16L22  POC1A2  WDSUB12  
    18/21 SIMAP similar genes for SNRNP40 using alignment to 2 protein entries:     SNR40_HUMAN (see all proteins) (see all similar genes):
    DKFZp434D199    WDR57    OK/SW-cl.41    DNAPTP3    UTY    FP6651
    KIAA1651    C14orf178    PF20    GNB5    WDR83    WSB1
    GNB1    WDR5B    WDR69    POC1B    WDR5    CORO1C

    SNRNP40 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SNRNP40
    PGOHUM00000250266


    Genomic Variants
    for SNRNP40 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/724 NCBI SNPs in SNRNP40 are shown (see all 724)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs787343391,2
    		F,--29875475(+) TTCCTC/TGTCTG 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs66605301,2
    		C,F,--29876439(+) CACCGC/TCCTCG 1 -- us2k13Minor allele frequency- T:0.41NA WA 122
    rs414123491,2
    		C,F,--29876452(+) TAGTCT/GCTTGT 1 -- us2k18Minor allele frequency- G:0.03NS EA NA CSA WA 550
    rs1138781061,2
    		C,--29877288(+) TTTCAG/AAGGAA 1 -- int12Minor allele frequency- A:0.04NA 122
    rs1121145791,2
    		C,--29878329(+) AGATTT/AGTGTT 1 -- int12Minor allele frequency- A:0.03CSA WA 120
    rs2021589581,2
    		C--31731955(+) AGGTTC/TTNNNN 1 -- ds50010--------
    rs120662851,2
    		A--31732140(+) tagtaA/Gagacg 1 -- ds50010--------
    rs1401387131,2
    		--31732197(+) GTGATA/C/TCGCCT 1 -- ds50010--------
    rs125654051,2
    		H--31732305(+) TCCTTC/TTAGTA 1 -- ds50014Minor allele frequency- T:0.00NS EA 418
    rs1913846921,2
    		--31732306(+) CCTTCC/TAGTAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for SNRNP40 (31732415 - 31769662 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for SNRNP40
         4 CNVs: 5483 2304 30381 3287

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    Disorders / Diseases
    for SNRNP40 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SNRNP40 for disorders           About GeneDecksing

    OMIM gene information: 607797    OMIM disorders: --

    5 diseases for SNRNP40:    About MalaCards
    charcot-marie-tooth neuropathy    cowpox    neuropathy    malaria
    intermediate charcot-marie-tooth neuropathy


    Export disorders for SNRNP40 gene to outside databases

    Publications
    for SNRNP40 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNRNP40 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with SNRNP40)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. (PubMed id 9731529)1, 2, 3 Neubauer G.... Mann M. (1998)
    2. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. (PubMed id 9774689)1, 2, 3 Achsel T.... Luehrmann R. (1998)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. (PubMed id 16723661)1, 2 Liu S.... Luehrmann R. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    7. The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. (PubMed id 10788320)1, 3 Makarov E.M.... Luehrmann R. (2000)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    10. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)

    External Searches for SNRNP40 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    		PubMed
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SNRNP40 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9410 HGNC: 30857 AceView: HPRP8BP Ensembl:ENSG00000060688 euGenes: HUgn9410
    ECgene: SNRNP40 Kegg: 9410 H-InvDB: SNRNP40

    Other Databases showing SNRNP40 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SNRNP40 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNRNP40 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SNRNP40 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SNRNP40 gene:
    Search GeneIP for patents involving SNRNP40

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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