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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNRNP40 Gene

protein-coding   GIFtS: 52
GCID: GC01M031732

Small Nuclear Ribonucleoprotein 40kDa (U5)

(Previous name: WD repeat domain 57 (U5 snRNP specific))
(Previous symbol: WDR57)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Small Nuclear Ribonucleoprotein 40kDa (U5)1 2     SPF382 5
WDR571 2 3     40K2
WD Repeat Domain 57 (U5 SnRNP Specific)1 2     HPRP8BP2
38 KDa-Splicing Factor2 3     RP11-490K7.32
PRP8BP2 3     U5 Small Nuclear Ribonucleoprotein 40 KDa Protein2
U5-40K2 3     U5 SnRNP-Specific 40 KDa Protein (HPrp8-Binding)2
Prp8-Binding Protein2 3     U5-40kD Protein2
U5 SnRNP 40 KDa Protein2 3     SFP383
WD Repeat-Containing Protein 572 3     hPRP8BP3
PRPF8BP2 5     U5 SnRNP-Specific 40 KDa Protein3

External Ids:    HGNC: 308571   Entrez Gene: 94102   Ensembl: ENSG000000606887   OMIM: 6077975   UniProtKB: Q96DI73   

Export aliases for SNRNP40 gene to outside databases

Previous GC identifers: GC01M031506 GC01M029838


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SNRNP40 Gene:
This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of
the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. (provided
by RefSeq, Jul 2008)

GeneCards Summary for SNRNP40 Gene: 
SNRNP40 (small nuclear ribonucleoprotein 40kDa (U5)) is a protein-coding gene. Diseases associated with SNRNP40 include intermediate charcot-marie-tooth neuropathy, and cowpox, and among its related super-pathways are mRNA Processing and Generic Transcription Pathway. GO annotations related to this gene include protein binding. An important paralog of this gene is WDR83.

UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7
Function: Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the
spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs

Gene Wiki entry for SNRNP40 (WDR57) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNRNP40 gene promoter:
         Pax-6   POU3F2   RORalpha2   NF-AT   AREB6   NF-AT4   NF-AT2   HOXA5   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNRNP40 promoter sequence
   Search SABiosciences Chromatin IP Primers for SNRNP40

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNRNP40


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.2   Ensembl cytogenetic band:  1p35.2   HGNC cytogenetic band: 1p35.2

SNRNP40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNRNP40 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M031732:  view genomic region     (about GC identifiers)

Start:
31,732,415 bp from pter      End:
31,769,662 bp from pter
Size:
37,248 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7 (See protein sequence)
Recommended Name: U5 small nuclear ribonucleoprotein 40 kDa protein  
Size: 357 amino acids; 39311 Da
Subunit: Identified in the spliceosome C complex. Part of the U5 snRNP complex. Interacts with PRPF8. Component of
the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8,
PRPF31, SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, NHP2L1, EFTUD2, SART1 and USP39
Subcellular location: Nucleus
Sequence caution: Sequence=AAC64084.1; Type=Frameshift; Positions=319; Note=An insertion/deletion of a short
nucleotide stretch in its cDNA resulting in a frameshift;
Secondary accessions: O75938 O95320

Explore the universe of human proteins at neXtProt for SNRNP40: NX_Q96DI7

Explore proteomics data for SNRNP40 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96DI7

  • SNRNP40 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SNRNP40 Protein Expression
    REFSEQ proteins: NP_004805.2  
    ENSEMBL proteins: 
     ENSP00000263694   ENSP00000362825   ENSP00000406841  
    Reactome Protein details: Q96DI7
    Human Recombinant Protein Products for SNRNP40: 
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    Cloud-Clone Corp. Proteins for SNRNP40 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005682U5 snRNP TAS9774689
    GO:0005730NOT nucleolus IDA--
    GO:0005732small nucleolar ribonucleoprotein complex NAS9774689

    SNRNP40 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep

    Graphical View of Domain Structure for InterPro Entry Q96DI7

    ProtoNet protein and cluster: Q96DI7

    UniProtKB/Swiss-Prot: SNR40_HUMAN, Q96DI7
    Similarity: Contains 7 WD repeats


    SNRNP40 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNR40_HUMAN, Q96DI7
    Function: Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the
    spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI9774689
         
    SNRNP40 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidSNRNP40 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SNRNP40 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    Processing of Capped Intron-Containing Pre-mRNA0.85
    mRNA processing0.46
    mRNA Processing0.85
    mRNA Splicing - Minor Pathway0.40
    mRNA Splicing - Major Pathway0.82
    Spliceosome0.31
    mRNA Splicing0.82
    2Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for SNRNP40
        mRNA processing

    5/6        Reactome Pathways for SNRNP40 (see all 6)
        mRNA Splicing - Major Pathway
    mRNA Splicing
    Gene Expression
    mRNA Processing
    mRNA Splicing - Minor Pathway


    1         Kegg Pathway  (Kegg details for SNRNP40):
        Spliceosome


    SNRNP40 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNRNP40

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/840 Interacting proteins for SNRNP40 (Q96DI71, 2, 3 ENSP000002636944) via UniProtKB, MINT, STRING, and/or I2D (see all 840)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRPF8Q6P2Q91, 2, 3, ENSP000003043504EBI-538492,EBI-538479 MINT-7945693 MINT-7947479 I2D: score=3 STRING: ENSP00000304350
    ENSG00000234078Q083452, 3, ENSP000004013974MINT-64071 I2D: score=5 STRING: ENSP00000401397
    DDR1Q083452, 3MINT-64071 I2D: score=5 
    ENSG00000137332Q083452, 3MINT-64071 I2D: score=5 
    ENSG00000215522Q083452, 3MINT-64071 I2D: score=5 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000375RNA splicing, via transesterification reactions TAS9774689
    GO:0000398mRNA splicing, via spliceosome TAS--
    GO:0006396RNA processing TAS9774689
    GO:0008380RNA splicing TAS--
    GO:0010467gene expression TAS--

    SNRNP40 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNRNP40 (SNR40)

    Search CenterWatch for drugs/clinical trials and news about SNRNP40 / SNR40

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SNRNP40 gene: 
    NM_004814.2  

    Unigene Cluster for SNRNP40:

    Small nuclear ribonucleoprotein 40kDa (U5)
    Hs.33962  [show with all ESTs]
    Unigene Representative Sequence: NM_004814
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263694(uc001bso.3 uc010oge.2) ENST00000486941 ENST00000489853
    ENST00000373720(uc009vtt.3) ENST00000491106 ENST00000474025 ENST00000463988
    ENST00000446633
    miRNA
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    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNRNP40

    Additional mRNA sequence: 

    AF090988.1 AK074516.1 AK298823.1 AK313800.1 BC001494.2 EF011621.1 

    10 DOTS entries:

    DT.208442  DT.91670632  DT.406654  DT.40230280  DT.95171446  DT.97807534  DT.100772918  DT.100783714 
    DT.120847331  DT.91855778 

    24/184 AceView cDNA sequences (see all 184):

    BM722186 BC001494 AL702450 CR605394 CA488652 BI917826 CR622464 CR611220 
    BM562019 BQ056159 BQ065130 CR624677 CR609455 BI819498 CR605147 AI678399 
    AK074516 BM905254 CR610792 BU167893 BQ057287 BQ677340 AL157420 AA288011 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNRNP40 expression in normal human tissues (normalized intensities)      SNRNP40 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGCTCCAT
    SNRNP40 Expression
    About this image


    SNRNP40 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/35 selected tissues (see all 35) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See SNRNP40 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNRNP40

    SOURCE GeneReport for Unigene cluster: Hs.33962
        SABiosciences Custom PCR Arrays for SNRNP40
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SNRNP40 gene from 10/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snrnp401 , 5 small nuclear ribonucleoprotein 40 (U5)1, 5 89.08(n)1
    98.32(a)1
      4 (63.43 cM)5
    665851  NM_025645.21  NP_079921.21 
     1303601325 
    chicken
    (Gallus gallus)
    Aves SNRNP401 small nuclear ribonucleoprotein 40kDa (U5) 79.44(n)
    92.8(a)
      419556  NM_001006308.1  NP_001006308.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNRNP406
    Uncharacterized protein
    84(a)
    1 ↔ 1
    GL343563.1(155788-163122)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC045034.12   -- 80.97(n)    BC045034.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc563122 similar to U5 snRNP-specific 40 kDa protein (hPrp8-binding) 77.62(n)   393292  BC051783.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG34361 CG3436 59.55(n)
    61.46(a)
      33180  NM_134657.2  NP_608501.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F08G12.21 Protein F08G12.2 58.18(n)
    56.21(a)
      181319  NM_077485.4  NP_509886.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PRP46
    Splicing factor, component of the U4/U6-U5 snRNP c...
    12(a)
    1 → many
    XVI(892332-893729)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G437701 Prp8 binding protein 60.65(n)
    59.94(a)
      818980  NM_129939.5  NP_181905.1 
    rice
    (Oryza sativa)
    Liliopsida Os.47362 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 75.28(n)    AK111971.1 


    ENSEMBL Gene Tree for SNRNP40 (if available)
    TreeFam Gene Tree for SNRNP40 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNRNP40 gene
    WDR832  POC1B2  WDR52  WDR482  ATG16L12  WDR5B2  PAFAH1B12  SMU12  
    DAW12  PRPF42  WDR382  ATG16L22  POC1A2  
    18/20 SIMAP similar genes for SNRNP40 using alignment to 2 protein entries:     SNR40_HUMAN (see all proteins) (see all similar genes):
    DKFZp434D199    WDR57    OK/SW-cl.41    DNAPTP3    UTY    FP6651
    KIAA1651    C14orf178    GNB1    PF20    GNB5    WDR83
    WSB1    DAW1    WDR5B    POC1B    WDR5    CORO1C

    SNRNP40 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SNRNP40
    PGOHUM00000250266


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/827 SNPs in SNRNP40 are shown (see all 827)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2021589581,2
    C--31731955(+) AGGTTC/TTNNNN 1 -- ds50010--------
    rs120662851,2
    A--31732140(+) tagtaA/Gagacg 1 -- ds50010--------
    rs1401387131,2
    C--31732197(+) GTGATA/C/TCGCCT 1 -- ds50010--------
    rs125654051,2
    H--31732305(+) TCCTTC/TTAGTA 1 -- ds50014Minor allele frequency- T:0.00NS EA 418
    rs1913846921,2
    --31732306(+) CCTTCC/TAGTAG 1 -- ds50010--------
    rs1827858081,2
    --31732319(+) AAAAAA/GTATTG 1 -- ds50010--------
    rs772798901,2
    C,F--31732333(+) CTGATA/C/GATTAT 1 -- ds50011EA 120
    rs1176560121,2
    F--31732337(+) TAATTA/TTTCTT 1 -- ds50011Minor allele frequency- T:0.02EA 120
    rs64257251,2
    C,H--31732390(+) GGGGGA/GAAAAA 1 -- ds500111Minor allele frequency- G:0.05NA WA CSA EA 375
    rs595918251,2
    C--31732603(+) GTTAC-/AAAAAA 1 -- ut312Minor allele frequency- A:0.25NA CSA 4

    HapMap Linkage Disequilibrium report for SNRNP40 (31732415 - 31769662 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SNRNP40:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv161067CNV Loss16902084
    nsv10051CNV Gain18304495
    dgv46e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607797    OMIM disorders: --

    4 diseases for SNRNP40:    About MalaCards
    intermediate charcot-marie-tooth neuropathy    cowpox    charcot-marie-tooth neuropathy    neuropathy


    SNRNP40 for disorders           About GeneDecksing


    Export disorders for SNRNP40 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNRNP40 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with SNRNP40)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. (PubMed id 9731529)1, 2, 3 Neubauer G.... Mann M. (1998)
    2. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. (PubMed id 9774689)1, 2, 3 Achsel T.... Luehrmann R. (1998)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. (PubMed id 16723661)1, 2 Liu S.... Luehrmann R. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    7. The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. (PubMed id 10788320)1, 3 Makarov E.M.... Luehrmann R. (2000)
    8. NKAIN1-SERINC2 is a functional, replicable and genome- wide significant risk gene region specific for alcohol dependence in subjects of European descent. (PubMed id 23455491)1 Zuo L....Luo X. (2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9410 HGNC: 30857 AceView: HPRP8BP Ensembl:ENSG00000060688 euGenes: HUgn9410
    ECgene: SNRNP40 Kegg: 9410 H-InvDB: SNRNP40

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNRNP40 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SNRNP40 gene:
    Search GeneIP for patents involving SNRNP40

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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