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Aliases for SNRNP25 Gene

Aliases for SNRNP25 Gene

  • Small Nuclear Ribonucleoprotein 25kDa (U11/U12) 2 3
  • U11/U12 SnRNP 25 KDa Protein 3 4
  • U11/U12 SnRNP 25K 2 3
  • Minus-99 Protein 3 4
  • C16orf33 3 4
  • U11/U12 Small Nuclear Ribonucleoprotein 25 KDa Protein 3
  • Chromosome 16 Open Reading Frame 33 2
  • U11/U12-25K 4

External Ids for SNRNP25 Gene

Previous HGNC Symbols for SNRNP25 Gene

  • C16orf33

Previous GeneCards Identifiers for SNRNP25 Gene

  • GC16P000044
  • GC16P000103
  • GC16P000022

Summaries for SNRNP25 Gene

Entrez Gene Summary for SNRNP25 Gene

  • Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 25K protein that is a component of the U12-type spliceosome. [provided by RefSeq, Apr 2010]

GeneCards Summary for SNRNP25 Gene

SNRNP25 (Small Nuclear Ribonucleoprotein 25kDa (U11/U12)) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNRNP25 Gene

Genomics for SNRNP25 Gene

Regulatory Elements for SNRNP25 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SNRNP25 Gene

53,010 bp from pter
57,669 bp from pter
4,660 bases
Plus strand

Genomic View for SNRNP25 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNRNP25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNRNP25 Gene

Proteins for SNRNP25 Gene

  • Protein details for SNRNP25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    U11/U12 small nuclear ribonucleoprotein 25 kDa protein
    Protein Accession:
    Secondary Accessions:
    • Q1W6H3
    • Q6IEF8
    • Q9H5W4

    Protein attributes for SNRNP25 Gene

    132 amino acids
    Molecular mass:
    15270 Da
    Quaternary structure:
    • Component of the U11/U12 snRNPs that are part of the U12-type spliceosome.

neXtProt entry for SNRNP25 Gene

Proteomics data for SNRNP25 Gene at MOPED

Post-translational modifications for SNRNP25 Gene

No Post-translational modifications

Other Protein References for SNRNP25 Gene

No data available for DME Specific Peptides for SNRNP25 Gene

Domains for SNRNP25 Gene

Protein Domains for SNRNP25 Gene

Suggested Antigen Peptide Sequences for SNRNP25 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 ubiquitin-like domain.
  • Contains 1 ubiquitin-like domain.
genes like me logo Genes that share domains with SNRNP25: view

No data available for Gene Families for SNRNP25 Gene

Function for SNRNP25 Gene

Gene Ontology (GO) - Molecular Function for SNRNP25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with SNRNP25: view

Phenotypes for SNRNP25 Gene

GenomeRNAi human phenotypes for SNRNP25:
genes like me logo Genes that share phenotypes with SNRNP25: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNRNP25

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNRNP25 Gene

Localization for SNRNP25 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SNRNP25 Gene

Subcellular locations from

Jensen Localization Image for SNRNP25 Gene COMPARTMENTS Subcellular localization image for SNRNP25 gene
Compartment Confidence
nucleus 5
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for SNRNP25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 18559850
GO:0005654 nucleoplasm IDA --
GO:0005689 U12-type spliceosomal complex IDA 15146077
GO:0005737 cytoplasm IDA --
GO:0045171 intercellular bridge IDA --
genes like me logo Genes that share ontologies with SNRNP25: view

Pathways for SNRNP25 Gene

SuperPathways for SNRNP25 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNRNP25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006397 mRNA processing IEA --
GO:0008380 RNA splicing IC 15146077
genes like me logo Genes that share ontologies with SNRNP25: view

No data available for Pathways by source for SNRNP25 Gene

Transcripts for SNRNP25 Gene

mRNA/cDNA for SNRNP25 Gene

Unigene Clusters for SNRNP25 Gene

Small nuclear ribonucleoprotein 25kDa (U11/U12):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNRNP25

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNRNP25 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
SP2: -

Relevant External Links for SNRNP25 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNRNP25 Gene

mRNA expression in normal human tissues for SNRNP25 Gene

Protein differential expression in normal tissues for SNRNP25 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SNRNP25 Gene

SOURCE GeneReport for Unigene cluster for SNRNP25 Gene Hs.15277

genes like me logo Genes that share expressions with SNRNP25: view

Expression partners for SNRNP25 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SNRNP25 Gene

Orthologs for SNRNP25 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SNRNP25 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SNRNP25 35
  • 88.35 (n)
  • 98.37 (a)
SNRNP25 36
  • 98 (a)
(Canis familiaris)
Mammalia SNRNP25 35
  • 89.9 (n)
  • 96.21 (a)
SNRNP25 36
  • 60 (a)
(Mus musculus)
Mammalia Snrnp25 35
  • 88.35 (n)
  • 98.37 (a)
Snrnp25 16
Snrnp25 36
  • 98 (a)
(Pan troglodytes)
Mammalia SNRNP25 35
  • 99.24 (n)
  • 100 (a)
SNRNP25 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Snrnp25 35
  • 88.35 (n)
  • 98.37 (a)
(Monodelphis domestica)
Mammalia SNRNP25 36
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia SNRNP25 36
  • 81 (a)
(Gallus gallus)
Aves C16ORF33 35
  • 73.54 (n)
  • 76.34 (a)
SNRNP25 36
  • 50 (a)
(Anolis carolinensis)
Reptilia SNRNP25 36
  • 62 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia snrnp25 35
  • 71.21 (n)
  • 81.06 (a)
Str.20169 35
African clawed frog
(Xenopus laevis)
Amphibia MGC68520 35
(Danio rerio)
Actinopterygii snrnp25 35
  • 70.45 (n)
  • 78.79 (a)
snrnp25 36
  • 60 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G07860 35
  • 46.5 (n)
  • 40.34 (a)
Species with no ortholog for SNRNP25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNRNP25 Gene

Gene Tree for SNRNP25 (if available)
Gene Tree for SNRNP25 (if available)

Paralogs for SNRNP25 Gene

(1) SIMAP similar genes for SNRNP25 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SNRNP25: view

No data available for Paralogs for SNRNP25 Gene

Variants for SNRNP25 Gene

Sequence variations from dbSNP and Humsavar for SNRNP25 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs10266 -- 57,162(+) ACAAC(C/G)CTCTT utr-variant-3-prime
rs216597 -- 56,777(+) GGGCA(C/G)CTGGA intron-variant
rs1045001 -- 57,275(+) AACAG(G/T)AACTG utr-variant-3-prime
rs11435836 -- 56,952(+) CACTG(-/C)CACTT intron-variant
rs11547280 -- 57,154(+) CAGAC(A/G)GGACA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SNRNP25 Gene

Variant ID Type Subtype PubMed ID
nsv904623 CNV Gain+Loss 21882294
dgv2455n71 CNV Loss 21882294
esv2422427 CNV Duplication 17116639
dgv789e1 CNV Complex 17122850
nsv522688 CNV Loss 19592680
nsv518291 CNV Loss 19592680
dgv2456n71 CNV Loss 21882294
nsv904628 CNV Loss 21882294
esv988339 CNV Deletion 20482838

Relevant External Links for SNRNP25 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNRNP25 Gene

Disorders for SNRNP25 Gene

No disorders were found for SNRNP25 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SNRNP25 Gene

Publications for SNRNP25 Gene

  1. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PMID: 15146077) Will C.L. … Luehrmann R. (RNA 2004) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4
  5. A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. (PMID: 16728641) De Gobbi M. … Higgs D.R. (Science 2006) 3 4

Products for SNRNP25 Gene

Sources for SNRNP25 Gene

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