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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNPH Gene

protein-coding   GIFtS: 53
GCID: GC20P001246

Syntaphilin

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
syntaphilin1 2
bA314N13.52
KIAA03743

External Ids:    HGNC: 159311   Entrez Gene: 97512   Ensembl: ENSG000001012987   OMIM: 6049425   UniProtKB: O150793   

Export aliases for SNPH gene to outside databases

Previous GC identifers: GC20P001235 GC20P001241 GC20P001194


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SNPH Gene:
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic
vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex
formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. (provided by RefSeq,
Jul 2008)

GeneCards Summary for SNPH Gene: 
SNPH (syntaphilin) is a protein-coding gene. Diseases associated with SNPH include normal pressure hydrocephalus, and hydrocephalus. GO annotations related to this gene include syntaxin-1 binding. An important paralog of this gene is SYBU.

UniProtKB/Swiss-Prot: SNPH_HUMAN, O15079
Function: Inhibits SNARE complex formation by absorbing free syntaxin-1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011387.8  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNPH gene promoter:
         NF-1/L   NF-1   Spz1   GATA-3   MyoD   GATA-1   GATA-2   POU2F1   POU2F1a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNPH promoter sequence
   Search SABiosciences Chromatin IP Primers for SNPH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNPH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

SNPH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNPH gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P001246:  view genomic region     (about GC identifiers)

Start:
1,246,960 bp from pter      End:
1,289,972 bp from pter
Size:
43,013 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SNPH_HUMAN, O15079 (See protein sequence)
Recommended Name: Syntaphilin  
Size: 494 amino acids; 53537 Da
Subunit: Binds to syntaxin-1
Subcellular location: Membrane; Single-pass membrane protein (Potential). Cell junction, synapse, synaptosome
Sequence caution: Sequence=BAA20829.2; Type=Erroneous initiation;
Secondary accessions: Q8IYI3
Alternative splicing: 2 isoforms:  O15079-1   O15079-2   

Explore the universe of human proteins at neXtProt for SNPH: NX_O15079

Explore proteomics data for SNPH at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O15079

  • SNPH Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SNPH Protein Expression
    REFSEQ proteins: NP_055538.2  
    ENSEMBL proteins: 
     ENSP00000371297   ENSP00000371291  

    Human Recombinant Protein Products for SNPH: 
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    OriGene Protein Over-expression Lysate for SNPH
    OriGene MassSpec for SNPH 
    OriGene Custom Protein Services for SNPH
    GenScript Custom Purified and Recombinant Proteins Services for SNPH
    Novus Biologicals SNPH Proteins
    Novus Biologicals SNPH Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for SNPH
    Cloud-Clone Corp. Proteins for SNPH 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005739mitochondrion ----
    GO:0005881cytoplasmic microtubule IDA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--

    SNPH for ontologies           About GeneDecksing



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    Novus Biologicals SNPH Antibodies
    Abcam antibodies for SNPH
    Cloud-Clone Corp. Antibodies for SNPH 
    ThermoFisher Antibodies for SNPH
    LSBio Antibodies in human, mouse, rat for SNPH 

    Assay Products for SNPH: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for SNPH 
    Cloud-Clone Corp. CLIAs for SNPH


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026196 Syntaphilin

    Graphical View of Domain Structure for InterPro Entry O15079

    ProtoNet protein and cluster: O15079


    SNPH for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNPH_HUMAN, O15079
    Function: Inhibits SNARE complex formation by absorbing free syntaxin-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0017075syntaxin-1 binding NAS10707983
         
    SNPH for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Snph):
     behavior/neurological  cellular  nervous system 

    SNPH for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Snphtm1Zhs for SNPH

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SNPH 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SNPH

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNPH 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNPH 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNPH
    8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate SNPH (see all 49):
    hsa-miR-194* hsa-miR-4291 hsa-miR-3664-5p hsa-miR-485-3p hsa-miR-301a hsa-miR-650 hsa-miR-764 hsa-miR-3122
    SwitchGear 3'UTR luciferase reporter plasmidSNPH 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SNPH
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for SNPH
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    GenScript: all cDNA clones in your preferred vector: SNPH (NM_014723)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNPH
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                         Customized lentivirus expression plasmids for stable overexpression of SNPH 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNPH


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SNPH

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SNPH (O150793 ENSP000003712974) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STX1AQ166233, ENSP000002228124I2D: score=1 STRING: ENSP00000222812
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007269neurotransmitter secretion NAS10707983
    GO:0007420brain development IEA--
    GO:0016081synaptic vesicle docking involved in exocytosis NAS10707983
    GO:0030182neuron differentiation IEA--

    SNPH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNPH

    Search CenterWatch for drugs/clinical trials and news about SNPH

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SNPH gene: 
    NM_014723.2  

    Unigene Cluster for SNPH:

    Syntaphilin
    Hs.323833  [show with all ESTs]
    Unigene Representative Sequence: AF187733
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381873(uc002wes.3) ENST00000381867(uc002wet.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNPH
    8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate SNPH (see all 49):
    hsa-miR-194* hsa-miR-4291 hsa-miR-3664-5p hsa-miR-485-3p hsa-miR-301a hsa-miR-650 hsa-miR-764 hsa-miR-3122
    SwitchGear 3'UTR luciferase reporter plasmidSNPH 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SNPH
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNPH
    Clone
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    OriGene clones in human, mouse for SNPH (see all 7)
    OriGene ORF clones in mouse, rat for SNPH
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNPH (NM_014723)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNPH
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNPH
    Sirion Biotech Customized lentivirus for stable overexpression of SNPH 
                         Customized lentivirus expression plasmids for stable overexpression of SNPH 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SNPH
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNPH
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNPH
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNPH

    Additional mRNA sequence: 

    AB002372.1 AF187733.1 BC035788.1 

    3 DOTS entries:

    DT.213879  DT.97824237  DT.100752050 

    24/79 AceView cDNA sequences (see all 79):

    AW955162 CK903800 AL119802 NM_014723 CB152741 BM547815 AF187733 CR597443 
    AI758880 BI962728 AB002372 BX957188 AA688133 BM987291 AA603105 BQ639449 
    BU729002 BX452539 BU145503 BQ068041 BX452540 CD625996 BQ009378 CB146104 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SNPH    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c
    SP1:                                                  -                                 
    SP2:                          -     -                 -                                 
    SP3:                          -     -           -                                       


    ECgene alternative splicing isoforms for SNPH

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNPH expression in normal human tissues (normalized intensities)      SNPH embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SNPH Expression
    About this image


    SNPH expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Smooth Muscle (Muscoskeletal System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Kidney (Urinary System)
             Juxtaglomerular Cells Afferent Arteriole

    See SNPH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNPH

    SOURCE GeneReport for Unigene cluster: Hs.323833

    UniProtKB/Swiss-Prot: SNPH_HUMAN, O15079
    Tissue specificity: Brain specific. Found in synapses

        SABiosciences Custom PCR Arrays for SNPH
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNPH

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SNPH gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snph1 , 5 syntaphilin1, 5 88.66(n)1
    92.06(a)1
      2 (74.83 cM)5
    2417271  NM_198214.21  NP_937857.11 
     1515905495 
    chicken
    (Gallus gallus)
    Aves LOC1008580581 syntaphilin-like 77.04(n)
    74.02(a)
      100858058  XM_003643233.1  XP_003643281.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNPH6
    Uncharacterized protein
    68(a)
    1 ↔ 1
    GL343346.1(765752-821065)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5699631 syntaphilin-like 60.55(n)
    57.72(a)
      569963  XM_693384.3  XP_698476.3 


    ENSEMBL Gene Tree for SNPH (if available)
    TreeFam Gene Tree for SNPH (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNPH gene
    SYBU2  
    1 SIMAP similar gene for SNPH using alignment to 1 protein entry:     SNPH_HUMAN:
    SYBU

    SNPH for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/958 SNPs in SNPH are shown (see all 958)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs672262351,2
    C--1218081(+) TAAAT-/ACACACACACACACAC/
    ACACACACACACACACACAC
    ACACA
    1 -- int11NA 2
    rs1146917221,2
    C,F--1244991(+) CCTTTG/TGTTTC 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1864197201,2
    --1245024(+) CTTATA/GTAATT 1 -- us2k10--------
    rs1913134371,2
    --1245060(+) CATTTG/TATCAA 1 -- us2k10--------
    rs1822525331,2
    --1245080(+) TAATAC/TAGCAT 1 -- us2k10--------
    rs1181350991,2
    F--1245146(+) CTATTC/TCTGCT 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs60783951,2
    C,F--1245158(+) AATTGC/TTCTGC 1 -- us2k11Minor allele frequency- T:0.01NA 120
    rs749880751,2
    F--1245189(+) AATATA/TATAAT 1 -- us2k11Minor allele frequency- T:0.12NA 120
    rs1869598991,2
    C--1245200(+) GGCTAC/TCTGAT 1 -- us2k10--------
    rs1443126581,2
    --1245340(+) AAGCAA/GCAGTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNPH (1246960 - 1289972 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for SNPH (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2722065CNV Deletion23290073
    nsv821480CNV Deletion20802225
    esv1588736CNV Deletion17803354
    esv2722066CNV Deletion23290073
    esv2722068CNV Deletion23290073
    esv1774028CNV Deletion17803354
    esv2722063CNV Deletion23290073
    esv2722069CNV Deletion23290073
    esv2722064CNV Deletion23290073
    esv2722067CNV Deletion23290073

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SNPH
    DNA2.0 Custom Variant and Variant Library Synthesis for SNPH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604942    OMIM disorders: --

    4 diseases for SNPH:    About MalaCards
    normal pressure hydrocephalus    hydrocephalus    multiple sclerosis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for SNPH:
    Normal pressure hydrocephalus

    SNPH for disorders           About GeneDecksing

    Genetic Association Database (GAD): SNPH
    Human Genome Epidemiology (HuGE) Navigator: SNPH (1 document)

    Export disorders for SNPH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNPH gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with SNPH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly. (PubMed id 10707983)1, 2, 3, 9 Lao G....Sheng Z.-H. (2000)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    4. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Syntaphilin binds to dynamin-1 and inhibits dynamin-dependent endocytosis. (PubMed id 12896979)1 Das S....Sheng Z.H. (2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Phosphorylation of syntaphilin by cAMP-dependent protein kinase modulates its interaction with syntaxin-1 and annuls its inhibitory effect on vesicle exocytosis. (PubMed id 14985338)9 Boczan J....Sheng Z.H. (2004)
    10. Mitochondrial changes within axons in multiple sclerosis. (PubMed id 19293237)9 Mahad D.J....Turnbull D.M. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9751 HGNC: 15931 AceView: SNPH Ensembl:ENSG00000101298 euGenes: HUgn9751
    ECgene: SNPH H-InvDB: SNPH

    (According to HUGE)
    About This Section
    HUGE: KIAA0374

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNPH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SNPH gene:
    Search GeneIP for patents involving SNPH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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