Subcategory (RNA class) for SNORD88B Gene
Quality Score for this RNA gene is
Previous GeneCards Identifiers for SNORD88B Gene
GeneCards Summary for SNORD88B Gene
SNORD88B (Small Nucleolar RNA, C/D Box 88B) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORD88B Gene - the ORGUL cluster for this gene includes several descriptions:
C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.
Small nucleolar RNA SNORD88: The members of this family belong to the C/D class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs . This family includes mouse MBII-211 and MBII-180 identified in  and the human orthologue HBII-180 (SNORD88). HBII-180 is predicted to guide the 2'O-ribose methylation of 28S rRNA C3680 .