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Aliases for SNORD59A Gene

Subcategory (RNA class) for SNORD59A Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD59A Gene

  • Small Nucleolar RNA, C/D Box 59A 2 3 5
  • RNA, U59 Small Nuclear 2 3
  • RNU59 3
  • U59 3

External Ids for SNORD59A Gene

Previous HGNC Symbols for SNORD59A Gene

  • RNU59

Previous GeneCards Identifiers for SNORD59A Gene

  • GC12M055327
  • GC12M057038
  • GC12M054078

Summaries for SNORD59A Gene

GeneCards Summary for SNORD59A Gene

SNORD59A (Small Nucleolar RNA, C/D Box 59A) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD59A Gene

Genomics for SNORD59A Gene

Regulatory Elements for SNORD59A Gene

Enhancers for SNORD59A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F056718 1.2 ENCODE 11 -77.5 -77458 8.9 CREB3L1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF416 ZNF548 ZNF263 MCM3 NEMP1 BAZ2A ANKRD52 RN7SL809P ENSG00000224713 TMEM198B ZC3H10 RNU6-343P CDK2 SMARCC2
GH12F056564 1.2 Ensembl ENCODE 9.9 +76.8 76827 7.9 HDGF ELF3 HDAC1 ARID4B ZNF48 RAD21 RARA SCRT2 CEBPB PPARG RBMS2 GLS2 BAZ2A SPRYD4 APOF ATP5B SNORD59A SNORD59B NACA GC12P056589
GH12F056695 1 ENCODE 11.7 -50.6 -50642 1.2 HDGF ATF1 SIN3A FEZF1 DMAP1 ZNF48 YY1 GLIS2 KLF13 KDM4B BAZ2A ZC3H10 RN7SL809P NACA CDK2 NEMP1 TMEM198B RNU6-343P ATP5B SNORD59A
GH12F056748 1.1 ENCODE 10.6 -105.9 -105859 4.1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF143 SP3 MXD4 BAZ2A RNU6-343P CDK2 RBMS2 LOC100131294 NEMP1 ATP5B RN7SL809P TMEM198B RPL41
GH12F056580 1 Ensembl ENCODE 10 +63.0 63023 2.5 KLF1 TEAD4 JUN NCOR1 EED NR2F6 MAFK SMARCE1 NR2F1 CEBPB RBMS2 GLS2 BAZ2A SNORD59A SNORD59B ATP5B NEMP1 GC12P056589
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORD59A on UCSC Golden Path with GeneCards custom track

Promoters for SNORD59A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000431281 -599 2201 PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143

Genomic Location for SNORD59A Gene

Chromosome:
12
Start:
56,645,027 bp from pter
End:
56,645,101 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for SNORD59A Gene

Genes around SNORD59A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD59A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD59A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD59A Gene

Proteins for SNORD59A Gene

Post-translational modifications for SNORD59A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD59A Gene

Domains & Families for SNORD59A Gene

Gene Families for SNORD59A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD59A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD59A Gene

Function for SNORD59A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD59A Gene

Localization for SNORD59A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD59A Gene

Pathways & Interactions for SNORD59A Gene

SuperPathways for SNORD59A Gene

No Data Available

Interacting Proteins for SNORD59A Gene

Gene Ontology (GO) - Biological Process for SNORD59A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD59A Gene

Transcripts for SNORD59A Gene

mRNA/cDNA for SNORD59A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD59A Gene

No ASD Table

Relevant External Links for SNORD59A Gene

GeneLoc Exon Structure for
SNORD59A
ECgene alternative splicing isoforms for
SNORD59A

Expression for SNORD59A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORD59A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD59A Gene:

SNORD59A
genes like me logo Genes that share expression patterns with SNORD59A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORD59A Gene

Orthologs for SNORD59A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD59A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD59 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD59 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD59 35
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25206 35
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORD59 35
  • 80 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORD59 35
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORD59 35
  • 79 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii SNORD59 35
  • 72 (a)
OneToOne
Species where no ortholog for SNORD59A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD59A Gene

ENSEMBL:
Gene Tree for SNORD59A (if available)
TreeFam:
Gene Tree for SNORD59A (if available)

Paralogs for SNORD59A Gene

No data available for Paralogs for SNORD59A Gene

Variants for SNORD59A Gene

Sequence variations from dbSNP and Humsavar for SNORD59A Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs111832585 -- 56,645,542(+) ATCCG(C/G)ATGCA intron-variant, upstream-variant-2KB
rs112925438 -- 56,646,881(+) GAGTT(A/C)GAGAC upstream-variant-2KB
rs114920447 -- 56,645,254(+) CCTCA(A/C/T)CAAAC upstream-variant-2KB, reference, missense
rs11542645 -- 56,645,321(-) CTTCG(C/T)CAAAA upstream-variant-2KB, reference, missense
rs11542646 -- 56,645,896(-) CCCTT(C/T)AGCGT upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for SNORD59A Gene

Variant ID Type Subtype PubMed ID
nsv482992 CNV gain+loss 15286789

Relevant External Links for SNORD59A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD59A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD59A Gene

Disorders for SNORD59A Gene

Relevant External Links for SNORD59A

Genetic Association Database (GAD)
SNORD59A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORD59A

No disorders were found for SNORD59A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD59A Gene

Publications for SNORD59A Gene

  1. Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PMID: 8674114) Kiss-LA!szlA^ Z. … Kiss T. (Cell 1996) 2 3 64
  2. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C. … Soranzo N. (Nature 2011) 46 64
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORD59A Gene

Sources for SNORD59A Gene

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