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Aliases for SNORD50A Gene

Subcategory (RNA class) for SNORD50A Gene

snoRNA

Quality Score for this RNA gene is

2

Aliases for SNORD50A Gene

  • Small Nucleolar RNA, C/D Box 50A 2 3
  • RNA, U50 Small Nuclear 2 3
  • RNU50 3
  • U50 3

External Ids for SNORD50A Gene

ORGUL Members for SNORD50A Gene

Previous HGNC Symbols for SNORD50A Gene

  • RNU50

Previous GeneCards Identifiers for SNORD50A Gene

  • GC06M086448
  • GC06M086452
  • GC06M086455
  • GC06M086458
  • GC06M086459
  • GC06M086463
  • GC06M086389
  • GC06M086391
  • GC06M083612
  • GC06M086393

Summaries for SNORD50A Gene

Entrez Gene Summary for SNORD50A Gene

  • SNORD50A belongs to the C/D box class of small nucleolar RNAs (snoRNAs), which are thought to function as guide RNAs in the site-specific ribose methylation of preribosomal RNA (Kiss-Laszlo et al., 1996 [PubMed 8674114]).[supplied by OMIM, Nov 2009]

GeneCards Summary for SNORD50A Gene

SNORD50A (Small Nucleolar RNA, C/D Box 50A) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD50A include Pleuropneumonia and Shipyard Eye.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD50A Gene

Genomics for SNORD50A Gene

Regulatory Elements for SNORD50A Gene

Enhancers for SNORD50A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G085640 1.4 ENCODE dbSUPER 12.8 +34.1 34076 5.3 MLX CREB3L1 AGO1 FEZF1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 SNHG5 SNORD50A SYNCRIP GC06P085634
GH06G085592 1.1 ENCODE 10.9 +83.4 83361 3.0 PKNOX1 CREB3L1 AGO1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF766 SNHG5 NT5E SYNCRIP SNORD50A SNX14 GC06M085515
GH06G085674 1.2 ENCODE 0.7 -0.3 -258 6.5 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SNHG5 GC06M085679 GC06M085686 SNORD50A SNORD50B
GH06G085675 0.7 ENCODE 0.7 +3.5 3501 1.0 AGO1 ZNF133 YY1 ZNF316 POLR2A PRDM10 NFE2 CBFB MAFG DPF2 GC06P085669 SNORD50A GC06M085686
GH06G085669 1.1 Ensembl ENCODE 0.4 +7.3 7326 1.9 HDGF TBL1XR1 NFIB ZNF366 CBX5 ZNF143 ZNF207 RELB ETV6 IKZF2 SNHG5 GC06P085669 GC06M085686 SNORD50A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORD50A on UCSC Golden Path with GeneCards custom track

Promoters for SNORD50A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000199719 -932 4201 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548

Genomic Location for SNORD50A Gene

Chromosome:
6
Start:
85,677,294 bp from pter
End:
85,677,368 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for SNORD50A Gene

Genes around SNORD50A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD50A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD50A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD50A Gene

Proteins for SNORD50A Gene

Post-translational modifications for SNORD50A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD50A Gene

Domains & Families for SNORD50A Gene

Gene Families for SNORD50A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD50A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD50A Gene

Function for SNORD50A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD50A Gene

Localization for SNORD50A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD50A Gene

Pathways & Interactions for SNORD50A Gene

SuperPathways for SNORD50A Gene

No Data Available

Interacting Proteins for SNORD50A Gene

Gene Ontology (GO) - Biological Process for SNORD50A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD50A Gene

Transcripts for SNORD50A Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD50A Gene

No ASD Table

Relevant External Links for SNORD50A Gene

GeneLoc Exon Structure for
SNORD50A
ECgene alternative splicing isoforms for
SNORD50A

No data available for mRNA/cDNA for SNORD50A Gene

Expression for SNORD50A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD50A Gene:

SNORD50A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD50A Gene

Orthologs for SNORD50A Gene

No data available for Orthologs and Evolution for SNORD50A Gene

Paralogs for SNORD50A Gene

No data available for Paralogs for SNORD50A Gene

Variants for SNORD50A Gene

Sequence variations from dbSNP and Humsavar for SNORD50A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000212406 -- 85,678,697(+) ACCTA(C/G/T)CACCC nc-transcript-variant, upstream-variant-2KB
rs1001045088 -- 85,678,907(+) CGCAG(A/G/T)CCGGC upstream-variant-2KB
rs1001491918 -- 85,678,694(+) CTCAC(A/C)TACCA nc-transcript-variant, upstream-variant-2KB
rs1001943933 -- 85,678,542(+) AGTAC(-/AT)GTGGC intron-variant, upstream-variant-2KB
rs1002543775 -- 85,679,154(+) AGCTG(-/GGCT)GGCTG nc-transcript-variant, upstream-variant-2KB

Relevant External Links for SNORD50A Gene

Human Gene Mutation Database (HGMD)
SNORD50A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD50A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORD50A Gene

Disorders for SNORD50A Gene

MalaCards: The human disease database

(3) MalaCards diseases for SNORD50A Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
pleuropneumonia
shipyard eye
  • ekc
opioid abuse
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SNORD50A

Genetic Association Database (GAD)
SNORD50A
Human Genome Epidemiology (HuGE) Navigator
SNORD50A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORD50A
genes like me logo Genes that share disorders with SNORD50A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD50A Gene

Publications for SNORD50A Gene

  1. Implication of snoRNA U50 in human breast cancer. (PMID: 19683667) Dong X.Y. … Dong J.T. (J Genet Genomics 2009) 3 46 64
  2. Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PMID: 8674114) Kiss-LA!szlA^ Z. … Kiss T. (Cell 1996) 2 3 64
  3. The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer. (PMID: 26595770) Siprashvili Z. … Khavari P.A. (Nat. Genet. 2016) 3 64
  4. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3 64
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORD50A Gene

Sources for SNORD50A Gene

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