Subcategory (RNA class) for SNORD46 Gene
Quality Score for this RNA gene is
Aliases for SNORD46 Gene
ORGUL Members for SNORD46 Gene
Previous HGNC Symbols for SNORD46 Gene
Previous GeneCards Identifiers for SNORD46 Gene
GeneCards Summary for SNORD46 Gene
SNORD46 (Small Nucleolar RNA, C/D Box 46) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORD46 Gene - the ORGUL cluster for this gene includes several descriptions:
C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.
nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.
Small nucleolar RNA SNORD46: U40 is a C/D box small nucleolar RNA, also known as snoZ153 in plants. The human sequence has also been annotated in the sequence databases as U46. U40 is encoded in intron 2 of the ribosomal protein S8 gene in human, and is hypothesised to guide methylation of 2'-O-ribose residues on 28S ribosomal RNA .