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Aliases for SNORD45A Gene

Subcategory (RNA class) for SNORD45A Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD45A Gene

  • Small Nucleolar RNA, C/D Box 45A 2 3 5
  • RNA, U45A Small Nuclear 2 3
  • RNU45A 3
  • U45a 3

External Ids for SNORD45A Gene

ORGUL Members for SNORD45A Gene

Previous HGNC Symbols for SNORD45A Gene

  • RNU45A

Previous GeneCards Identifiers for SNORD45A Gene

  • GC01P076026
  • GC01P076255
  • GC01P074383
  • GC01P076258
  • GC01P076264
  • GC01P076272
  • GC01P075788
  • GC01P075790
  • GC01P075791
  • GC01P075792
  • GC01P075794
  • GC01P075795

Summaries for SNORD45A Gene

GeneCards Summary for SNORD45A Gene

SNORD45A (Small Nucleolar RNA, C/D Box 45A) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORD45A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD45A Gene

Genomics for SNORD45A Gene

GeneHancer (GH) Regulatory Elements for SNORD45A Gene

Promoters and enhancers for SNORD45A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I075784 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 550.8 +0.1 55 7.7 PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B RABGGTB GC01P075797 GC01P075799 GC01P075800 SNORD45A SNORD45B SNORD45C MSH4 DLSTP1 ACADM
GH01I075722 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 12.2 -62.8 -62777 6 HDGF PKNOX1 FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ACADM ENSG00000178193 SLC44A5 RABGGTB SNORD45A SNORD45C MSH4 PIR54256
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORD45A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD45A gene promoter:

Genomic Locations for SNORD45A Gene

Genomic Locations for SNORD45A Gene
chr1:75,787,889-75,787,972
(GRCh38/hg38)
Size:
84 bases
Orientation:
Plus strand
chr1:76,253,574-76,253,657
(GRCh37/hg19)

Genomic View for SNORD45A Gene

Genes around SNORD45A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD45A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD45A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD45A Gene

Proteins for SNORD45A Gene

Post-translational modifications for SNORD45A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD45A Gene

Domains & Families for SNORD45A Gene

Gene Families for SNORD45A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD45A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD45A Gene

Function for SNORD45A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD45A Gene

Localization for SNORD45A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD45A Gene

Pathways & Interactions for SNORD45A Gene

SuperPathways for SNORD45A Gene

No Data Available

Interacting Proteins for SNORD45A Gene

Gene Ontology (GO) - Biological Process for SNORD45A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD45A Gene

Drugs & Compounds for SNORD45A Gene

No Compound Related Data Available

Transcripts for SNORD45A Gene

mRNA/cDNA for SNORD45A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD45A Gene

No ASD Table

Relevant External Links for SNORD45A Gene

GeneLoc Exon Structure for
SNORD45A
ECgene alternative splicing isoforms for
SNORD45A

Expression for SNORD45A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD45A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD45A Gene:

SNORD45A
genes like me logo Genes that share expression patterns with SNORD45A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD45A Gene

Orthologs for SNORD45A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD45A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD45 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD45 34
  • 92 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORD45 34
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm24494 34
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD45 34
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORD45 34
  • 78 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORD45 34
  • 82 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORD45 34
  • 80 (a)
OneToMany
Species where no ortholog for SNORD45A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD45A Gene

ENSEMBL:
Gene Tree for SNORD45A (if available)
TreeFam:
Gene Tree for SNORD45A (if available)

Paralogs for SNORD45A Gene

No data available for Paralogs for SNORD45A Gene

Variants for SNORD45A Gene

Sequence variations from dbSNP and Humsavar for SNORD45A Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1001038088 -- 75,786,209(+) G/A upstream_transcript_variant
rs1003034074 -- 75,788,102(+) A/G downstream_transcript_variant
rs1003391502 -- 75,787,707(+) C/T upstream_transcript_variant
rs1004746443 -- 75,786,576(+) G/C upstream_transcript_variant
rs1005225516 -- 75,786,391(+) ACAG/ACAGACAG upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD45A Gene

Variant ID Type Subtype PubMed ID
nsv519329 CNV gain 19592680

Additional Variant Information for SNORD45A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD45A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD45A Gene

Disorders for SNORD45A Gene

Additional Disease Information for SNORD45A

No disorders were found for SNORD45A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD45A Gene

Publications for SNORD45A Gene

  1. Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PMID: 8674114) Kiss-László Z … Kiss T (Cell 1996) 2 3 58
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  3. The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells. (PMID: 28029658) Penna I … Pagano A (Oncotarget 2017) 3

Products for SNORD45A Gene

Sources for SNORD45A Gene

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