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Aliases for SNORD25 Gene

Subcategory (RNA class) for SNORD25 Gene


Quality Score for this RNA gene is


Aliases for SNORD25 Gene

  • Small Nucleolar RNA, C/D Box 25 2 3 5
  • RNA, U25 Small Nucleolar 2 3
  • RNU25 3
  • U25 3

External Ids for SNORD25 Gene

ORGUL Members for SNORD25 Gene

Previous HGNC Symbols for SNORD25 Gene

  • RNU25

Previous GeneCards Identifiers for SNORD25 Gene

  • GC11M062400
  • GC11M062408
  • GC11M062418
  • GC11M062427
  • GC11M062631
  • GC11M062636
  • GC11M058957
  • GC11M062645
  • GC11M062650
  • GC11M062655
  • GC11M062662
  • GC11M062672
  • GC11M062861
  • GC11M062871
  • GC11M062880
  • GC11M062891

Summaries for SNORD25 Gene

GeneCards Summary for SNORD25 Gene

SNORD25 (Small Nucleolar RNA, C/D Box 25) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORD25 Gene - the ORGUL cluster for this gene includes several descriptions:

  • C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.

  • Small nucleolar RNA SNORD25: U25 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U25 is found in gene clusters in plants [1], and within the U22 snoRNA host gene (UHG) in mammals [2]. U25 is thought to as a 2'-O-ribose methylation guide for ribosomal RNA. This RNA has also been named snoRNA R73 in some plants.

View fRNAdb secondary structures for SNORD25

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD25 Gene

Genomics for SNORD25 Gene

Regulatory Elements for SNORD25 Gene

Enhancers for SNORD25 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F062852 1.3 FANTOM5 ENCODE 0.8 -0.2 -206 5.9 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC METTL12 INTS5 NXF1 SNHG1 UBXN1 MTA2 EML3 MIR6748 LOC105369332 STX5
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SNORD25 on UCSC Golden Path with GeneCards custom track

Promoters for SNORD25 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000563384 -768 4401 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC

Genomic Location for SNORD25 Gene

62,855,564 bp from pter
62,855,632 bp from pter
69 bases
Minus strand

Genomic View for SNORD25 Gene

Genes around SNORD25 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD25 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD25 Gene

ORGUL Member Location for SNORD25 Gene

ORGUL Member Location for SNORD25 gene

Proteins for SNORD25 Gene

Post-translational modifications for SNORD25 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD25 Gene

Domains & Families for SNORD25 Gene

Gene Families for SNORD25 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD25: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD25 Gene

Function for SNORD25 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD25 Gene

Localization for SNORD25 Gene

Subcellular locations from

Jensen Localization Image for SNORD25 Gene COMPARTMENTS Subcellular localization image for SNORD25 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SNORD25 Gene

Pathways & Interactions for SNORD25 Gene

SuperPathways for SNORD25 Gene

No Data Available

Interacting Proteins for SNORD25 Gene

Gene Ontology (GO) - Biological Process for SNORD25 Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORD25 Gene

Transcripts for SNORD25 Gene

fRNAdb Secondary structures for SNORD25 Gene

  • FR302959

mRNA/cDNA for SNORD25 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD25 Gene

No ASD Table

Relevant External Links for SNORD25 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORD25 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD25 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORD25 Gene

Orthologs for SNORD25 Gene

Evolution for SNORD25 Gene

Gene Tree for SNORD25 (if available)
Gene Tree for SNORD25 (if available)

No data available for Orthologs for SNORD25 Gene

Paralogs for SNORD25 Gene

No data available for Paralogs for SNORD25 Gene

Variants for SNORD25 Gene

Sequence variations from dbSNP and Humsavar for SNORD25 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1059292 -- 62,855,579(-) GATAA(A/G)TAACT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs111884916 -- 62,856,349(+) GGCTG(A/G)TGTCC upstream-variant-2KB, reference, missense
rs111973482 -- 62,856,531(+) TTCTT(C/T)AGATC intron-variant, upstream-variant-2KB
rs11231252 -- 62,857,299(+) TTTGT(A/G)TTTTT intron-variant, upstream-variant-2KB
rs112885679 -- 62,855,793(+) CAATC(G/T)CTCAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORD25 Gene

Variant ID Type Subtype PubMed ID
nsv1159903 CNV duplication 26073780
nsv508636 CNV deletion 20534489
nsv509416 CNV insertion 20534489

Relevant External Links for SNORD25 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD25 Gene

Disorders for SNORD25 Gene

Relevant External Links for SNORD25

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SNORD25 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD25 Gene

Publications for SNORD25 Gene

  1. The U22 host gene (UHG): chromosomal localization of UHG and distribution of U22 small nucleolar RNA. (PMID: 9387929) Frey M.R. … Matera A.G. (Histochem. Cell Biol. 1997) 2 3 64
  2. A mammalian gene with introns instead of exons generating stable RNA products. (PMID: 8559254) Tycowski K.T. … Steitz J.A. (Nature 1996) 1 3 64
  3. Genomic analysis of high-risk smoldering multiple myeloma. (PMID: 22331267) LA^pez-Corral L. … GutiAcrrez N.C. (Haematologica 2012) 3 64
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  5. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1

Products for SNORD25 Gene

Sources for SNORD25 Gene

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