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Aliasesfor SNORD24 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section GeneCards Plus Subcategory (RNA class): snoRNAQuality score for this RNA gene is 11 Aliases Small Nucleolar RNA, C/D Box 24 1 2 RNU241 2 RNA, U24 Small Nucleolar1 U242
External Ids: HGNC: 10146 1 Entrez Gene: 26820 2 Ensembl: ENSG00000206611 7 Export aliases for SNORD24 gene to outside databases Previous GC identifers: GC09U900790 GC09P135219 GC09P135227 GC09P135232 GC09P135239 GC09P136217 GC09P136247 GC09P136261
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Summariesfor SNORD24 gene (According to Entrez Gene ,
GeneCards ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section GeneCards Plus GeneCards Summary for SNORD24 Gene: SNORD24 (small nucleolar RNA, C/D box 24) is an RNA gene, and is affiliated with the snoRNA class. fRNAdb sequence ontologies for SNORD24 - the ORGUL cluster for this gene includes several descriptions: Small nucleolar RNA SNORD24 - U24 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs [1]. C/D box snoRNAs have been shown to act as methylation guides for a number of RNA targets [2,3]. U24 is encoded within an intron of the gene for ribosomal protein L7a in mammals, chicken and Fugu [4]. The U76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene [5]. snoRNAs Z20 and U76 snoRNAs show clear similarity to U24. C_D_box_snoRNA - Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.View fRNAdb secondary structures for SNORD24
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Genomic Viewsfor SNORD24 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 75) ,
Regulatory elements and Epigenetics data according to
QIAGEN , and/or
SwitchGear Genomics )About This Section GeneCards Plus Regulatory elements: Regulatory transcription factor binding sites in the SNORD24 gene promoter:ER-alpha HOXA3 HTF Pax-2 Pax-2a FOXL1 Pax-2b Chx10 Sox9 PPAR-gamma2 Other transcription factors Search Chromatin IP Primers for SNORD24 Epigenetics: DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNORD24
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9q34 Ensembl cytogenetic band: 9q34.2 HGNC cytogenetic band: 9q34.2 SNORD24 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09P136283: view genomic region
(about GC identifiers )
Start: 136,216,251 bp from pter End:
136,216,325 bp from pter
Size: 75 bases Orientation:
plus strand
1 alternative location : Chr 9+,NW_003315925 175,490-175,564
ORGUL member locations:Legend (see complete legend)
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Proteinsfor SNORD24 gene
(According to
1 UniProtKB ,
HORDE ,
2 neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Antibodies by
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section GeneCards Plus UniProtKB: --
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Domains /for SNORD24 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section GeneCards Plus HGNC Gene Families: SNORD: ncRNAs / Small nucleolar RNAs : C/D box containing
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Functionfor SNORD24 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
genOway ,
QIAGEN
and/or HOMER ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
Gene Editing from DNA2.0 ,
Clones from OriGene ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
ESI BIO ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Animal Models: Cell Line GenScript Custom overexpressing Cell Line Services for SNORD24 Browse ESI BIO Cell Lines and PureStem Progenitors for SNORD24 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNORD24
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Localizationfor SNORD24 gene
(According to UniProtKB , COMPARTMENTS Subcellular localization database ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus
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Pathways & Interactionsfor SNORD24 gene
(SuperPaths according to PathCards ,
Pathways according to
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
QIAGEN ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene) .
About This Section GeneCards Plus SuperPaths for SNORD24 About See pathways by source 1 Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNORD24 Interactions: Search GeneGlobe Interaction Network for SNORD24
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Drugs & Compoundsfor SNORD24 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience ,
ApexBio ,
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB )
About This Section GeneCards Plus Browse compounds at ApexBio Browse Tocris compounds for SNORD24
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Transcriptsfor SNORD24 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
OriGene ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene , and/or
QIAGEN
)About This Section GeneCards Plus 2 fRNAdb Secondary structures: 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000383884(snoRNA) GeneLoc Exon Structure
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Expression for SNORD24 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MaxQB ,
plus additional links to
SOURCE , and/or
BioGPS , and/or
UniProtKB ,QIAGEN ,
Primers from
OriGene , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GeneCards Plus Expression evidence for SNORD24:H-invDB
SNORD24 expression in normal human tissues
(normalized intensities) SNORD24 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
SNORD24 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells DatabaseSNORD24 Protein expression data from MOPED1 2 3 : Custom PCR Arrays for SNORD24 Primer Browse OriGene qPCR Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat SNORD24 Search QuantiTect SYBR Green Assays in human, mouse, rat SNORD24 Search QuantiFast Probe-based Assays in human, mouse, rat SNORD24 In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNORD24
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Orthologsfor SNORD24 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section GeneCards Plus Orthologs for SNORD24 gene from Selected species (see all 9 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves SNORD246
Small nucleolar RNA SNORD24
84(a)
1 ↔ 1
17(6866555-6866629) ENSGALG00000017832
zebrafish Actinopterygii SNORD246
Small nucleolar RNA SNORD24
81(a)
1 ↔ 1
5(34904485-34904556)
Species with no ortholog for SNORD24 ENSEMBL Gene Tree for SNORD24 (if available)TreeFam Gene Tree for SNORD24 (if available)
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Paralogsfor SNORD24 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section GeneCards Plus
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Genomic Variantsfor SNORD24 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) , the Human Cytochrome P450 Allele
Nomenclature Database , and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN )
About This Section GeneCards Plus Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 9 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for SNORD24 (136216251 - 136216325 bp)
Structural Variations Database of Genomic Variants (DGV) 6 variations for SNORD24 : About this table Site Specific Mutation Identification with PCR Assays
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Disorders
/ Diseasesfor SNORD24 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section GeneCards Plus OMIM information: 185640 156240 606613 About GeneDecksing Export disorders for SNORD24 gene to outside databases
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Publicationsfor SNORD24 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section GeneCards Plus PubMed articles for SNORD24 gene, integrated from 10 sources (see all 15 ):(articles sorted by number of sources associating them with SNORD24) Utopia : connect your pdf to the dynamic
Human L7a ribosomal protein: sequence, structural organization, and expression of a functional gene. (PubMed id 8482538) 1 , 3(Gene 1993) Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729) 1 (J. Proteome Res. 2012) Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PubMed id 19446021) 1 (Genomics 2009) Evolution of U24 and U36 snoRNAs encoded within introns of vertebrate rpL7a gene homologs: unique features of mammalian U36 variants. (PubMed id 9703018) 1 (DNA Cell Biol. 1998) Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs. (PubMed id 8674114) 1 (Cell 1996) U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementarities to 28S rRNA. (PubMed id 7651828) 1 (Nucleic Acids Res. 1995) (PubMed id 8764399) 10 (PubMed id 11606788) 10 (PubMed id 8797828) 10 (PubMed id 10736225) 10
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External Searches for SNORD24 gene (in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section GeneCards Plus
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Genome Databases showing SNORD24 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section GeneCards Plus
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Other Databases showing SNORD24 gene
(According to HUGE )
About This Section GeneCards Plus --
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Specialized Databases showing SNORD24 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , UniProtKB/TrEMBL , and/or others, e.g. Wikipedia and GeneReviews , via UniProtKB/Swiss-Prot )About This Section GeneCards Plus
Name Description PharmGKB entry for SNORD24 Pharmacogenomics, SNPs, Pathways
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About This Section GeneCards Plus Patent Information for SNORD24 gene: SNORD24 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SNORD24 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 . Clones from OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , and ESI BIO , PCR Arrays from QIAGEN , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , Enzo Life Sciences , and/or
ApexBio , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory ,
genOway )About This Section GeneCards Plus
Block miRNA regulation of human, mouse, rat SNORD24 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SNORD24 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNORD24 Predesigned siRNA for gene silencing in human mouse rat Search QuantiFast Probe-based Assays in human, mouse, rat SNORD24 Search QuantiTect SYBR Green Assays in human, mouse, rat SNORD24 Custom PCR Arrays for SNORD24 Search Chromatin IP Primers for SNORD24 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat SNORD24 Search GeneGlobe Interaction Network for SNORD24 Regulatory tfbs in SNORD24 promoter
Search Tocris compounds for SNORD24
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNORD24
Search ThermoFisher Antibodies for SNORD24
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNORD24
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