Subcategory (RNA class) for SNORD24 Gene
Quality Score for this RNA gene is
Aliases for SNORD24 Gene
ORGUL Members for SNORD24 Gene
Previous HGNC Symbols for SNORD24 Gene
Previous GeneCards Identifiers for SNORD24 Gene
GeneCards Summary for SNORD24 Gene
SNORD24 (Small Nucleolar RNA, C/D Box 24) is an RNA Gene, and is affiliated with the snoRNA class. Among its related pathways are CFTR translational fidelity (class I mutations).
fRNAdb sequence ontologies for SNORD24 Gene - the ORGUL cluster for this gene includes several descriptions:
C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.
Small nucleolar RNA SNORD24: U24 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs . C/D box snoRNAs have been shown to act as methylation guides for a number of RNA targets [2,3]. U24 is encoded within an intron of the gene for ribosomal protein L7a in mammals, chicken and Fugu . The U76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene . snoRNAs Z20 and U76 snoRNAs show clear similarity to U24.