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Aliases for SNORD21 Gene

Subcategory (RNA class) for SNORD21 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD21 Gene

  • Small Nucleolar RNA, C/D Box 21 2 3 5
  • RNA, U21 Small Nucleolar 2
  • U21 Small Nucleolar RNA 3
  • RNA, U21 Small Nuclear 3
  • U21 SnoRNA 3
  • RNU21 3
  • U21 3

External Ids for SNORD21 Gene

ORGUL Members for SNORD21 Gene

Previous HGNC Symbols for SNORD21 Gene

  • RNU21

Previous GeneCards Identifiers for SNORD21 Gene

  • GC01P093075
  • GC01P093302

Summaries for SNORD21 Gene

Entrez Gene Summary for SNORD21 Gene

  • This gene encodes a small nucleolar RNA (snoRNA) that may be involved in biogenesis of the large (28S) ribosomal subunit. This gene is found within an intron of the RPL5 gene. [provided by RefSeq, Mar 2009]

GeneCards Summary for SNORD21 Gene

SNORD21 (Small Nucleolar RNA, C/D Box 21) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD21 Gene

Genomics for SNORD21 Gene

Regulatory Elements for SNORD21 Gene

Enhancers for SNORD21 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F093078 0.6 ENCODE 53.6 +243.1 243147 4.5 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 CCDC18-AS1 SNORA66 SNORD21 RPL5 DNTTIP2 DR1 LOC100289500 ACTBP12 MTCO3P21 ENSG00000230439
GH01F093177 1.1 ENCODE 50.5 +342.7 342735 4.7 PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF302 ZNF416 CCDC18-AS1 SNORA66 SNORD21 RPL5 DNTTIP2 LOC100289500 MTCO3P21 ACTBP12 ENSG00000233482 DR1
GH01F092831 0.4 ENCODE 41.4 -3.9 -3861 4.2 CREB3L1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 SNORA66 SNORD21 CCDC18-AS1 ENSG00000230439 RPL5 LOC100289500 ACTBP12 DR1 FAM69A GC01P092832
GH01F092803 1.2 FANTOM5 Ensembl ENCODE 38.1 -32.2 -32232 3.1 PKNOX1 ATF1 ARNT CREB3L1 GTF3C2 ZNF121 GATA2 FOS NFYC NCOA1 SNORD21 SNORA66 CCDC18-AS1 RPL5 DR1 RPAP2 EVI5 GC01M092807
GH01F093811 1 Ensembl ENCODE 35.7 +978.0 977971 8.3 PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 ZNF48 ZNF2 ZNF143 DEK ENSG00000230439 SNORA66 CCDC18-AS1 SNORD21 RPL5 TRR-TCT1-1 DR1 BCAR3 MIR760 DNTTIP2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SNORD21 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORD21 Gene

Chromosome:
1
Start:
92,837,289 bp from pter
End:
92,837,383 bp from pter
Size:
95 bases
Orientation:
Plus strand

Genomic View for SNORD21 Gene

Genes around SNORD21 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD21 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD21 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD21 Gene

Proteins for SNORD21 Gene

Post-translational modifications for SNORD21 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD21 Gene

Domains & Families for SNORD21 Gene

Gene Families for SNORD21 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD21: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD21 Gene

Function for SNORD21 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD21 Gene

Localization for SNORD21 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD21 Gene

Pathways & Interactions for SNORD21 Gene

SuperPathways for SNORD21 Gene

No Data Available

Interacting Proteins for SNORD21 Gene

Gene Ontology (GO) - Biological Process for SNORD21 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD21 Gene

Transcripts for SNORD21 Gene

mRNA/cDNA for SNORD21 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD21 Gene

No ASD Table

Relevant External Links for SNORD21 Gene

GeneLoc Exon Structure for
SNORD21
ECgene alternative splicing isoforms for
SNORD21

Expression for SNORD21 Gene

mRNA expression in normal human tissues for SNORD21 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD21 Gene:

SNORD21
genes like me logo Genes that share expression patterns with SNORD21: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORD21 Gene

Orthologs for SNORD21 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD21 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD21 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD21 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD21 35
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snord21 35
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORD21 35
  • 84 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORD21 35
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORD21 35 35
  • 75 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORD21 35
  • 58 (a)
OneToOne
Species where no ortholog for SNORD21 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD21 Gene

ENSEMBL:
Gene Tree for SNORD21 (if available)
TreeFam:
Gene Tree for SNORD21 (if available)

Paralogs for SNORD21 Gene

No data available for Paralogs for SNORD21 Gene

Variants for SNORD21 Gene

Sequence variations from dbSNP and Humsavar for SNORD21 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs121434406 Pathogenic 92,836,283(+) AGCCA(A/G)GTGCC intron-variant, upstream-variant-2KB, reference, missense
rs587777118 Pathogenic 92,837,592(+) AGAAA(C/T)AGTTC intron-variant, downstream-variant-500B, reference, stop-gained
rs878854146 Uncertain significance 92,836,191(+) ATAGC(C/T)TCTCA intron-variant, upstream-variant-2KB, reference, missense
rs11540832 Benign 92,837,557(+) GCGCT(A/G)CTTAA intron-variant, downstream-variant-500B, reference, missense
rs183825489 Benign 92,836,186(+) CTTGA(A/C/G)TAGCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORD21 Gene

Variant ID Type Subtype PubMed ID
esv2714684 CNV deletion 23290073
nsv1008602 CNV gain 25217958
nsv508393 CNV deletion 20534489
nsv946078 CNV duplication 23825009

Relevant External Links for SNORD21 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD21

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD21 Gene

Disorders for SNORD21 Gene

Relevant External Links for SNORD21

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORD21

No disorders were found for SNORD21 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD21 Gene

Publications for SNORD21 Gene

  1. U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals. (PMID: 7937132) Qu L.H. … Bachellerie J.-P. (Nucleic Acids Res. 1994) 2 3 64
  2. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 3 64
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORD21 Gene

Sources for SNORD21 Gene

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