SNORD14A Gene
RNA gene GIFtS : 17
GCID: GC11 M017096
small nucleolar RNA, C/D box 14A (Previous names: RNA, U14 small nucleolar ) (Previous symbol: RNU14 )
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Aliasesfor SNORD14A gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Subcategory (RNA class): snoRNAQuality score for this RNA gene is 6 Aliases Small Nucleolar RNA, C/D Box 14A 1 2 RNU141 2 RNU14A1 2 U141 2 RNA, U14 Small Nucleolar1 U14-S13-52
External Ids: HGNC: 10113 1 Entrez Gene: 26822 2 Ensembl: ENSG00000201784 7 Export aliases for SNORD14A gene to outside databases Previous GC identifer: GC11M017063
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Summariesfor SNORD14A gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section fRNAdb sequence ontology for SNORD14A: C_D_box_snoRNA - Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.View fRNAdb secondary structures for SNORD14A
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Genomic Viewsfor SNORD14A gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SNORD14A gene promoter: Nkx3-1 v2 Nkx3-1 AP-2rep Nkx3-1 v4 p53 AP-1 HFH-1 Nkx3-1 v3 Nkx3-1 v1 YY1 Other transcription factors Search SABiosciences Chromatin IP Primers for SNORD14A Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNORD14A
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 11p15 Ensembl cytogenetic band: 11p15.1 HGNC cytogenetic band: 11p15.1 SNORD14A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 11 GeneLoc Exon Structure
GeneLoc location for GC11M017096: view genomic region
(about GC identifiers )
Start:
17,096,200 bp from pter
End:
17,096,291 bp from pter
Size:
92 bases
Orientation:
minus strand
ORGUL member locations:Legend (see complete legend)
FR0397771
FR0402194
FR0168985
17096199 17096245 17096291 chr11
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Proteinsfor SNORD14A gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --
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Protein
Domains / Familiesfor SNORD14A gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Functionfor SNORD14A gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor SNORD14A gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNORD14A
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Drugs & Compoundsfor SNORD14A gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SNORD14A Search CenterWatch for drugs/clinical trials and news about SNORD14A
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Transcriptsfor SNORD14A gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 3 fRNAdb Secondary structures: 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000364914(snoRNA) 24/1408 AceView cDNA sequences (see all 1408 ):
BM310022 BQ946032 F20705 AI678928 AI817402 W94223 BG661045 BE785055 T71230 AA343539 AI630269 BQ581413 BE908412 BU859809 BM887870 AA297417 BM894359 AI734831 AI333614 F21570 AA330191 CB240921 BM739047 BM090669 GeneLoc Exon Structure
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Expression for SNORD14A gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section Expression evidence for SNORD14A:none
SNORD14A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image SABiosciences Custom PCR Arrays for SNORD14A Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SNORD14A Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNORD14A Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNORD14A
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Orthologsfor SNORD14A gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of human and mouse.
Orthologs for SNORD14A gene from 1 species (see representative species ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
mouse (Mus musculus)
Mammalia
Snord14a5
small nucleolar RNA, C/D box 14A
--
 
7 (61.62 cM) 116333171
ENSEMBL Gene Tree for SNORD14A (if available)TreeFam Gene Tree for SNORD14A (if available)
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Paralogsfor SNORD14A gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor SNORD14A gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor SNORD14A gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor SNORD14A gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SNORD14A gene, integrated from 9 sources (see all 21 ): (articles sorted by number of sources associating them with SNORD14A) Utopia : connect your pdf to the dynamic world of online information
U14 snoRNAs are encoded in introns of human ribosomal protein S13 gene. (PubMed id 8920921) 1 , 3, 9 Kenmochi N.... Tanaka T. (1996) Eukaryotic snoRNAs: a paradigm for gene expression fl exibility. (PubMed id 19446021) 1 Dieci G....Montanini B. (2009) Delocalization of some small nucleolar RNPs after actinomycin D treatment to deplete early pre-rRNAs. (PubMed id 9211978) 9 Rivera-Leon R. and Gerbi S.A. (1997) Unique features of Chinese hamster S13 gene relative to its human and Xenopus analogs. (PubMed id 10390155) 9 Chen M.S. and Laszlo A. (1999) Amplification and altered expression of the hsc70/U14 snoRNA gene in a heat resistant Chinese hamster cell line. (PubMed id 9222589) 9 Chen M.S....Laszlo A. (1996) Genomic organisation of plant U14 snoRNA genes. (PubMed id 7672345) 9 Leader D.J....Brown J.W. (1995) Localization and processing from a polycistronic prec ursor of novel snoRNAs in maize. (PubMed id 9664033) 9 Shaw P.J....Brown J.W. (1998) (PubMed id 8668536) 10 (PubMed id 8797828) 10 (PubMed id 10736225) 10
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External Searches for SNORD14A gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SNORD14A gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing SNORD14A gene
(According to HUGE )
About This Section --
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Specialized Databases showing SNORD14A gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for SNORD14A Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for SNORD14A gene: Search GeneIP for patents involving SNORD14A GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SNORD14A gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNORD14A Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNORD14A QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNORD14A QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat SNORD14A Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNORD14A Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNORD14A
Search ThermoFisher Antibodies for SNORD14A
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNORD14A
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