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Aliases for SNORD12B Gene

Subcategory (RNA class) for SNORD12B Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD12B Gene

  • Small Nucleolar RNA, C/D Box 12B 2 3 5

External Ids for SNORD12B Gene

ORGUL Members for SNORD12B Gene

Previous GeneCards Identifiers for SNORD12B Gene

  • GC19U900762
  • GC20P047898
  • GC20P047904
  • GC20P047909
  • GC20P047916
  • GC20P049283
  • GC20P049289
  • GC20P049293
  • GC20P049297
  • GC20P049301
  • GC20P049307
  • GC20P049311

Summaries for SNORD12B Gene

GeneCards Summary for SNORD12B Gene

SNORD12B (Small Nucleolar RNA, C/D Box 12B) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORD12B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD12B Gene

Genomics for SNORD12B Gene

GeneHancer (GH) Regulatory Elements for SNORD12B Gene

Promoters and enhancers for SNORD12B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I049275 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 587.6 -0.4 -358 9.2 CLOCK MLX ZFP64 FEZF1 DMAP1 YBX1 IRF4 YY1 SLC30A9 ZNF213 ZNFX1 SNORD12B ZFAS1 SNORD12 ENSG00000277830 ENSG00000277967 GC20P049313 GC20P049317 GC20P049318 GC20P049319
GH20I050186 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 19.4 +911.0 910965 10.3 CLOCK MLX ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 CEBPB GC20P050191 CEBPB-AS1 ADNP DDX27 DPM1 MOCS3 ENSG00000232043 SNORD12B LINC01273
GH20I049981 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 19.4 +703.2 703218 3.3 HDGF PKNOX1 CLOCK SMAD1 MLX ZFP64 ARID4B SIN3A YBX1 DMAP1 SNAI1 DDX27 ADNP ENSG00000232043 SNORD12B SLC9A8 MOCS3 RNF114 PSMD10P1 DPM1
GH20I049914 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 9.9 +636.2 636249 4.9 MLX YBX1 DMAP1 YY1 SLC30A9 E2F8 ZNF143 SP3 MEF2D ZNF610 SPATA2 LOC105372653 DDX27 SLC9A8 ENSG00000232043 RNF114 PSMD10P1 LINC01273 CSE1L SNORD12B
GH20I049184 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 10 -93.7 -93689 4.8 HDGF PKNOX1 FOXA2 SMAD1 MLX ARNT ZFP64 ARID4B SIN3A IRF4 STAU1 DDX27 CSE1L SNORD12B ARFGEF2 ZFAS1 PREX1 GC20M049182 PIR47119
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORD12B on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD12B gene promoter:

Genomic Locations for SNORD12B Gene

Genomic Locations for SNORD12B Gene
chr20:49,280,313-49,280,415
(GRCh38/hg38)
Size:
103 bases
Orientation:
Plus strand
chr20:47,896,850-47,896,952
(GRCh37/hg19)

Genomic View for SNORD12B Gene

Genes around SNORD12B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD12B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD12B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD12B Gene

Proteins for SNORD12B Gene

Post-translational modifications for SNORD12B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD12B Gene

Domains & Families for SNORD12B Gene

Gene Families for SNORD12B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD12B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD12B Gene

Function for SNORD12B Gene

Phenotypes From GWAS Catalog for SNORD12B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD12B Gene

Localization for SNORD12B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD12B Gene

Pathways & Interactions for SNORD12B Gene

SuperPathways for SNORD12B Gene

No Data Available

Interacting Proteins for SNORD12B Gene

Gene Ontology (GO) - Biological Process for SNORD12B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD12B Gene

Drugs & Compounds for SNORD12B Gene

No Compound Related Data Available

Transcripts for SNORD12B Gene

mRNA/cDNA for SNORD12B Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORD12B Gene

Small nucleolar RNA, C/D box 12B:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD12B Gene

No ASD Table

Relevant External Links for SNORD12B Gene

GeneLoc Exon Structure for
SNORD12B
ECgene alternative splicing isoforms for
SNORD12B

Expression for SNORD12B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD12B Gene

mRNA differential expression in normal tissues according to GTEx for SNORD12B Gene

This gene is overexpressed in Whole Blood (x8.4).

NURSA nuclear receptor signaling pathways regulating expression of SNORD12B Gene:

SNORD12B

SOURCE GeneReport for Unigene cluster for SNORD12B Gene:

Hs.711216
genes like me logo Genes that share expression patterns with SNORD12B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD12B Gene

Orthologs for SNORD12B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD12B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD12 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD12 34
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD12 34
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23201 34
  • 80 (a)
ManyToMany
Gm24123 34
  • 69 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORD12 34 34 34 34 34
  • 68 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia SNORD12 34 34
  • 64 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORD12 34
  • 71 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORD12 34
  • 63 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii SNORD12 34 34 34
  • 64 (a)
ManyToMany
Species where no ortholog for SNORD12B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD12B Gene

ENSEMBL:
Gene Tree for SNORD12B (if available)
TreeFam:
Gene Tree for SNORD12B (if available)

Paralogs for SNORD12B Gene

No data available for Paralogs for SNORD12B Gene

Variants for SNORD12B Gene

Sequence variations from dbSNP and Humsavar for SNORD12B Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000070514 -- 49,279,695(+) T/C upstream_transcript_variant
rs1001655437 -- 49,280,476(+) T/C downstream_transcript_variant
rs1003210719 -- 49,279,407(+) C/G/T upstream_transcript_variant
rs1004241048 -- 49,280,077(+) A/T upstream_transcript_variant
rs1004465473 -- 49,279,581(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD12B Gene

Variant ID Type Subtype PubMed ID
dgv1248e212 CNV loss 25503493
nsv1064443 CNV gain 25217958
nsv1067146 CNV loss 25217958
nsv437839 CNV loss 16327808

Additional Variant Information for SNORD12B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD12B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD12B Gene

Disorders for SNORD12B Gene

Additional Disease Information for SNORD12B

No disorders were found for SNORD12B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD12B Gene

Publications for SNORD12B Gene

  1. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  2. snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PMID: 16990247) Yang JH … Qu LH (Nucleic acids research 2006) 3 58
  3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for SNORD12B Gene

Sources for SNORD12B Gene

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