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Aliases for SNORD121B Gene

Subcategory (RNA class) for SNORD121B Gene

snoRNA

Quality Score for this RNA gene is

4

Aliases for SNORD121B Gene

  • Small Nucleolar RNA, C/D Box 121B 2 3 5

External Ids for SNORD121B Gene

Previous GeneCards Identifiers for SNORD121B Gene

  • GC09U900872
  • GC09M033924
  • GC09P033892

Summaries for SNORD121B Gene

GeneCards Summary for SNORD121B Gene

SNORD121B (Small Nucleolar RNA, C/D Box 121B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORD121B Gene

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

Additional gene information for SNORD121B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD121B Gene

Genomics for SNORD121B Gene

GeneHancer (GH) Regulatory Elements for SNORD121B Gene

Promoters and enhancers for SNORD121B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I033934 Promoter 1 EPDnew 550.8 0.0 -12 0.1 SOX5 SOX13 GATAD2A FOXA2 NFIA FOXA3 HMG20A RARA CEBPA CREB1 GC09M033934 SNORD121B UBAP2 DCAF12 GC09M033952 SNORD121A
GH09I033835 Enhancer 1.1 Ensembl ENCODE dbSUPER 10.9 +98.1 98094 2.2 ZNF211 MAX CEBPG BATF IRF4 POLR2A PRDM10 FOS IKZF2 RUNX3 SNORD121B UBAP2 SNORD121A UBE2R2 NUDT2 KIF24 C9orf24 ENSG00000200834 GC09P034128
GH09I033852 Enhancer 1 Ensembl ENCODE dbSUPER 10.8 +82.1 82075 0.6 HDGF CTCF STAT1 ZNF654 REST RAD21 CC2D1A GATA3 SMC3 ZNF143 UBE2R2 SNORD121B UBAP2 SNORD121A DCAF12 GC09P034128 ENSG00000200834
GH09I033880 Enhancer 0.8 Ensembl dbSUPER 11.2 +53.5 53475 0.2 CC2D1A ZFHX2 ZNF189 ZNF398 ZNF600 ZIC2 ZBTB5 EGR2 ZBTB17 UBE2R2 SNORD121B UBAP2 SNORD121A ENSG00000228352 RNU2-50P RNU4ATAC11P GC09M033934
GH09I034226 Enhancer 0.9 ENCODE 9.8 -292.2 -292202 0.2 FOXA2 MLX ARID4B THRB RAD21 RARA YY1 SLC30A9 THAP11 MIXL1 GC09M034226 RPS8P9 IMPDH1P1 DCAF12 ENSG00000228352 RNU2-50P UBAP2 SNORD121B SNORD121A PIR43374
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORD121B on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD121B gene promoter:

Genomic Locations for SNORD121B Gene

Genomic Locations for SNORD121B Gene
chr9:33,934,296-33,934,376
(GRCh38/hg38)
Size:
81 bases
Orientation:
Minus strand
chr9:33,934,294-33,934,374
(GRCh37/hg19)

Genomic View for SNORD121B Gene

Genes around SNORD121B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD121B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD121B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD121B Gene

ORGUL Member Location for SNORD121B Gene

ORGUL Member Location for SNORD121B gene

Proteins for SNORD121B Gene

Post-translational modifications for SNORD121B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD121B Gene

Domains & Families for SNORD121B Gene

Gene Families for SNORD121B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD121B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD121B Gene

Function for SNORD121B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD121B Gene

Localization for SNORD121B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD121B Gene

Pathways & Interactions for SNORD121B Gene

SuperPathways for SNORD121B Gene

No Data Available

Interacting Proteins for SNORD121B Gene

Gene Ontology (GO) - Biological Process for SNORD121B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD121B Gene

Drugs & Compounds for SNORD121B Gene

No Compound Related Data Available

Transcripts for SNORD121B Gene

mRNA/cDNA for SNORD121B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD121B Gene

No ASD Table

Relevant External Links for SNORD121B Gene

GeneLoc Exon Structure for
SNORD121B
ECgene alternative splicing isoforms for
SNORD121B

Expression for SNORD121B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD121B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD121B Gene:

SNORD121B
genes like me logo Genes that share expression patterns with SNORD121B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD121B Gene

Orthologs for SNORD121B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD121B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD121A 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD121A 34
  • 91 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD121A 34
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm22888 34
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORD121A 34
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORD121A 34
  • 67 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORD121A 34
  • 65 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORD121A 34
  • 66 (a)
OneToOne
Species where no ortholog for SNORD121B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD121B Gene

ENSEMBL:
Gene Tree for SNORD121B (if available)
TreeFam:
Gene Tree for SNORD121B (if available)

Paralogs for SNORD121B Gene

No data available for Paralogs for SNORD121B Gene

Variants for SNORD121B Gene

Sequence variations from dbSNP and Humsavar for SNORD121B Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000417903 -- 33,934,174(-) A/G downstream_transcript_variant
rs1000460362 -- 33,934,615(-) C/A upstream_transcript_variant
rs1001800700 -- 33,936,021(-) C/T upstream_transcript_variant
rs1002081745 -- 33,935,555(-) C/T upstream_transcript_variant
rs1002134245 -- 33,935,790(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD121B Gene

Variant ID Type Subtype PubMed ID
esv3620335 CNV gain 21293372
nsv1125318 OTHER inversion 24896259
nsv520467 CNV gain 19592680
nsv614153 CNV loss 21841781
nsv831541 CNV loss 17160897

Additional Variant Information for SNORD121B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD121B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD121B Gene

Disorders for SNORD121B Gene

Additional Disease Information for SNORD121B

No disorders were found for SNORD121B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD121B Gene

Publications for SNORD121B Gene

  1. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  2. snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PMID: 16990247) Yang JH … Qu LH (Nucleic acids research 2006) 3 58
  3. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1
  4. Integrative annotation of 21,037 human genes validated by full-length cDNA clones. (PMID: 15103394) Imanishi T … Sugano S (PLoS biology 2004) 1

Products for SNORD121B Gene

Sources for SNORD121B Gene

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