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Aliases for SNORD116-18 Gene

Subcategory (RNA class) for SNORD116-18 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD116-18 Gene

  • Small Nucleolar RNA, C/D Box 116-18 2 3
  • HBII-85-18 3

External Ids for SNORD116-18 Gene

ORGUL Members for SNORD116-18 Gene

Previous GeneCards Identifiers for SNORD116-18 Gene

  • GC15P023256
  • GC15P023306
  • GC15U900911
  • GC15P023445
  • GC15P023526
  • GC15P023625
  • GC15P025330
  • GC15P003466

Summaries for SNORD116-18 Gene

GeneCards Summary for SNORD116-18 Gene

SNORD116-18 (Small Nucleolar RNA, C/D Box 116-18) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD116-18 include multiple myeloma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD116-18 Gene

Genomics for SNORD116-18 Gene

Regulatory Elements for SNORD116-18 Gene

Transcription factor binding sites by QIAGEN in the SNORD116-18 gene promoter:

Genomic Location for SNORD116-18 Gene

Start:
25,085,384 bp from pter
End:
25,085,477 bp from pter
Size:
94 bases
Orientation:
Plus strand

Genomic View for SNORD116-18 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORD116-18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD116-18 Gene

Proteins for SNORD116-18 Gene

Post-translational modifications for SNORD116-18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD116-18 Gene

Domains for SNORD116-18 Gene

Gene Families for SNORD116-18 Gene

HGNC:
  • SNORD :ncRNAs / Small nucleolar RNAs : C/D box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD116-18: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD116-18 Gene

Function for SNORD116-18 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORD116-18 Gene

Localization for SNORD116-18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD116-18 Gene

Pathways for SNORD116-18 Gene

SuperPathways for SNORD116-18 Gene

No Data Available

Interacting Proteins for SNORD116-18 Gene

Gene Ontology (GO) - Biological Process for SNORD116-18 Gene

None

No data available for Pathways by source for SNORD116-18 Gene

Transcripts for SNORD116-18 Gene

mRNA/cDNA for SNORD116-18 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORD116-18
    • Block miRNA regulation of SNORD116-18 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORD116-18

    Primer Products

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for SNORD116-18 Gene

    No ASD Table

    Relevant External Links for SNORD116-18 Gene

    GeneLoc Exon Structure for
    SNORD116-18
    ECgene alternative splicing isoforms for
    SNORD116-18

    Expression for SNORD116-18 Gene

    mRNA expression in normal human tissues for SNORD116-18 Gene

    mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

    genes like me logo Genes that share expressions with SNORD116-18: view

    In Situ Assay Products

    No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SNORD116-18 Gene

    Orthologs for SNORD116-18 Gene

    This gene was present in the common ancestor of human and mouse.

    Orthologs for SNORD116-18 Gene

    Organism Taxonomy Gene Similarity Type Details
    chimpanzee
    (Pan troglodytes)
    Mammalia SNORD116 36
    • 99 (a)
    OneToOne
    mouse
    (Mus musculus)
    Mammalia Gm22373 36
    • 70 (a)
    ManyToMany
    Species with no ortholog for SNORD116-18:
    • A. gosspyii yeast (Ashbya gossypii)
    • Actinobacteria (Mycobacterium tuberculosis)
    • African clawed frog (Xenopus laevis)
    • African malaria mosquito (Anopheles gambiae)
    • Alicante grape (Vitis vinifera)
    • alpha proteobacteria (Wolbachia pipientis)
    • amoeba (Dictyostelium discoideum)
    • Archea (Pyrococcus horikoshii)
    • baker's yeast (Saccharomyces cerevisiae)
    • barley (Hordeum vulgare)
    • beta proteobacteria (Neisseria meningitidis)
    • bread mold (Neurospora crassa)
    • chicken (Gallus gallus)
    • Chromalveolata (Phytophthora infestans)
    • common water flea (Daphnia pulex)
    • corn (Zea mays)
    • cow (Bos Taurus)
    • dog (Canis familiaris)
    • E. coli (Escherichia coli)
    • filamentous fungi (Aspergillus nidulans)
    • Firmicute bacteria (Streptococcus pneumoniae)
    • fission yeast (Schizosaccharomyces pombe)
    • fruit fly (Drosophila melanogaster)
    • green algae (Chlamydomonas reinhardtii)
    • honey bee (Apis mellifera)
    • K. lactis yeast (Kluyveromyces lactis)
    • lizard (Anolis carolinensis)
    • loblloly pine (Pinus taeda)
    • malaria parasite (Plasmodium falciparum)
    • medicago trunc (Medicago Truncatula)
    • moss (Physcomitrella patens)
    • oppossum (Monodelphis domestica)
    • orangutan (Pongo pygmaeus)
    • pig (Sus scrofa)
    • platypus (Ornithorhynchus anatinus)
    • rainbow trout (Oncorhynchus mykiss)
    • rat (Rattus norvegicus)
    • rice (Oryza sativa)
    • rice blast fungus (Magnaporthe grisea)
    • schistosome parasite (Schistosoma mansoni)
    • sea anemone (Nematostella vectensis)
    • sea squirt (Ciona intestinalis)
    • sea squirt (Ciona savignyi)
    • sea urchin (Strongylocentrotus purpuratus)
    • sorghum (Sorghum bicolor)
    • soybean (Glycine max)
    • stem rust fungus (Puccinia graminis)
    • sugarcane (Saccharum officinarum)
    • thale cress (Arabidopsis thaliana)
    • tomato (Lycopersicon esculentum)
    • toxoplasmosis (Toxoplasma gondii)
    • Trichoplax (Trichoplax adhaerens)
    • tropical clawed frog (Silurana tropicalis)
    • wheat (Triticum aestivum)
    • worm (Caenorhabditis elegans)
    • zebrafish (Danio rerio)

    Evolution for SNORD116-18 Gene

    ENSEMBL:
    Gene Tree for SNORD116-18 (if available)
    TreeFam:
    Gene Tree for SNORD116-18 (if available)

    Paralogs for SNORD116-18 Gene

    No data available for Paralogs for SNORD116-18 Gene

    Variants for SNORD116-18 Gene

    Sequence variations from dbSNP and Humsavar for SNORD116-18 Gene

    SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
    rs7171937 -- 25,084,400(+) ATAAT(A/G)AGTGT upstream-variant-2KB
    rs60697534 -- 25,084,486(+) GCTTG(C/T)GATGT upstream-variant-2KB
    rs76417418 -- 25,084,322(+) GCAGA(C/G)TGACT upstream-variant-2KB
    rs77212704 -- 25,084,494(+) TGTTA(G/T)GTTAT upstream-variant-2KB
    rs181876109 -- 25,084,204(+) CAGAG(C/T)GACGA upstream-variant-2KB

    Structural Variations from Database of Genomic Variants (DGV) for SNORD116-18 Gene

    Variant ID Type Subtype PubMed ID
    esv29021 CNV Gain+Loss 19812545
    nsv903721 CNV Gain 21882294

    Relevant External Links for SNORD116-18 Gene

    HapMap Linkage Disequilibrium report
    SNORD116-18

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNORD116-18 Gene

    Disorders for SNORD116-18 Gene

    MalaCards: The human disease database

    MalaCards: The human disease database. (1) Diseases for SNORD116-18 Gene including...

    Search for SNORD116-18 Gene in MalaCards »
    genes like me logo Genes that share disorders with SNORD116-18: view

    No data available for UniProtKB/Swiss-Prot for SNORD116-18 Gene

    Publications for SNORD116-18 Gene

    1. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. (PMID: 11106375) CavaillAc J. … HA1ttenhofer A. (Proc. Natl. Acad. Sci. U.S.A. 2000) 2 3
    2. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. (PMID: 11726556) Runte M. … Buiting K. (Hum. Mol. Genet. 2001) 2 3
    3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
    4. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3

    Products for SNORD116-18 Gene

    Sources for SNORD116-18 Gene

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