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Aliases for SNORD116-11 Gene

Subcategory (RNA class) for SNORD116-11 Gene


Quality Score for this RNA gene is


Aliases for SNORD116-11 Gene

  • Small Nucleolar RNA, C/D Box 116-11 2 3
  • HBII-85-11 3

External Ids for SNORD116-11 Gene

ORGUL Members for SNORD116-11 Gene

Previous GeneCards Identifiers for SNORD116-11 Gene

  • GC15P023247
  • GC15P023332
  • GC15U900915
  • GC15P023438
  • GC15P023520
  • GC15P023619
  • GC15P025321
  • GC15P003456

Summaries for SNORD116-11 Gene

GeneCards Summary for SNORD116-11 Gene

SNORD116-11 (Small Nucleolar RNA, C/D Box 116-11) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORD116-11 Gene - the ORGUL cluster for this gene includes several descriptions:

  • C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.

  • Small nucleolar RNA SNORD116: HBII-85 is a member of the C/D class of snoRNAs, which contain the C (UGAUGA) and D (CUGA) box motifs. HBII-85 is encoded in a tandemly repeated array with another C/D snoRNA, HBII-52, in the Prader-Willi syndrome (PWS) region of chromosome 15. Unlike most other snoRNAs, HBII-85 is expressed prevalently in the brain (but is absent in PWS patients) and lacks any significant complementarity with ribosomal RNA.

View fRNAdb secondary structures for SNORD116-11

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD116-11 Gene

Genomics for SNORD116-11 Gene

Regulatory Elements for SNORD116-11 Gene

Transcription factor binding sites by QIAGEN in the SNORD116-11 gene promoter:

Genomic Location for SNORD116-11 Gene

25,075,928 bp from pter
25,076,021 bp from pter
94 bases
Plus strand

Genomic View for SNORD116-11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORD116-11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD116-11 Gene

ORGUL Member Location for SNORD116-11 Gene

ORGUL Member Location for SNORD116-11 gene

Proteins for SNORD116-11 Gene

Post-translational modifications for SNORD116-11 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD116-11 Gene

Domains for SNORD116-11 Gene

Gene Families for SNORD116-11 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD116-11: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD116-11 Gene

Function for SNORD116-11 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD116-11 Gene

Localization for SNORD116-11 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD116-11 Gene

Pathways for SNORD116-11 Gene

SuperPathways for SNORD116-11 Gene

No Data Available

Interacting Proteins for SNORD116-11 Gene

Gene Ontology (GO) - Biological Process for SNORD116-11 Gene


No data available for Pathways by source for SNORD116-11 Gene

Transcripts for SNORD116-11 Gene

fRNAdb Secondary structures for SNORD116-11 Gene

  • FR360468

mRNA/cDNA for SNORD116-11 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD116-11 Gene

No ASD Table

Relevant External Links for SNORD116-11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORD116-11 Gene

mRNA expression in normal human tissues for SNORD116-11 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with SNORD116-11: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SNORD116-11 Gene

Orthologs for SNORD116-11 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for SNORD116-11 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Gm22373 36
  • 71 (a)
(Pan troglodytes)
Mammalia SNORD116 36
  • 99 (a)
Species with no ortholog for SNORD116-11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD116-11 Gene

Gene Tree for SNORD116-11 (if available)
Gene Tree for SNORD116-11 (if available)

Paralogs for SNORD116-11 Gene

No data available for Paralogs for SNORD116-11 Gene

Variants for SNORD116-11 Gene

Sequence variations from dbSNP and Humsavar for SNORD116-11 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs17115162 -- 25,074,845(+) AGGCT(C/T)TTTAA upstream-variant-2KB
rs73358005 -- 25,074,971(+) TAAGA(C/G)TGTGT upstream-variant-2KB
rs76024299 -- 25,074,987(+) CCCAC(A/G)TCGTG upstream-variant-2KB
rs112539040 -- 25,074,795(+) TGTGC(C/T)TTTAC upstream-variant-2KB
rs112654995 -- 25,075,049(+) TCAGC(A/G)TCTCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORD116-11 Gene

Variant ID Type Subtype PubMed ID
esv29021 CNV Gain+Loss 19812545

Relevant External Links for SNORD116-11 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNORD116-11 Gene

Disorders for SNORD116-11 Gene

No disorders were found for SNORD116-11 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SNORD116-11 Gene

Publications for SNORD116-11 Gene

  1. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. (PMID: 11106375) CavaillAc J. … HA1ttenhofer A. (Proc. Natl. Acad. Sci. U.S.A. 2000) 2 3
  2. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. (PMID: 11726556) Runte M. … Buiting K. (Hum. Mol. Genet. 2001) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3

Products for SNORD116-11 Gene

Sources for SNORD116-11 Gene

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