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Aliases for SNORD115-48 Gene

Subcategory (RNA class) for SNORD115-48 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD115-48 Gene

  • Small Nucleolar RNA, C/D Box 115-48 2 3 5
  • HBII-52-48 3

External Ids for SNORD115-48 Gene

ORGUL Members for SNORD115-48 Gene

Previous GeneCards Identifiers for SNORD115-48 Gene

  • GC15U900726
  • GC15P023497
  • GC15P023568
  • GC15P023664
  • GC15P025515
  • GC15P003639
  • GC15P025518
  • GC15P025521
  • GC15P025533
  • GC15P025592
  • GC15P025707
  • GC15P025281
  • GC15P025390
  • GC15P025489
  • GC15P025546
  • GC15P025618

Summaries for SNORD115-48 Gene

GeneCards Summary for SNORD115-48 Gene

SNORD115-48 (Small Nucleolar RNA, C/D Box 115-48) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD115-48 Gene

Genomics for SNORD115-48 Gene

Regulatory Elements for SNORD115-48 Gene

Enhancers for SNORD115-48 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G025317 0.4 FANTOM5 11.1 +48.3 48322 0.3 ATF2 SNORD115-48 SNORD109B UBE3A SNURF SNRPN ENSG00000261529
GH15G025320 0.4 FANTOM5 11.1 +51.3 51289 1.3 ZNF316 SNORD115-48 SNORD109B UBE3A SNRPN SNURF ENSG00000261529
GH15G025319 0.3 FANTOM5 11.1 +49.5 49480 0.2 SNORD115-48 SNORD109B UBE3A SNRPN SNURF ENSG00000261529
GH15G025327 0.2 ENCODE 10.9 +58.1 58129 1.0 SNORD109B SNORD115-48 UBE3A ENSG00000261529
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORD115-48 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the SNORD115-48 gene promoter:

Genomic Location for SNORD115-48 Gene

Chromosome:
15
Start:
25,269,783 bp from pter
End:
25,269,858 bp from pter
Size:
76 bases
Orientation:
Plus strand

Genomic View for SNORD115-48 Gene

Genes around SNORD115-48 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD115-48 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD115-48 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD115-48 Gene

Proteins for SNORD115-48 Gene

Post-translational modifications for SNORD115-48 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD115-48 Gene

Domains & Families for SNORD115-48 Gene

Gene Families for SNORD115-48 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD115-48: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD115-48 Gene

Function for SNORD115-48 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD115-48 Gene

Localization for SNORD115-48 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD115-48 Gene

Pathways & Interactions for SNORD115-48 Gene

SuperPathways for SNORD115-48 Gene

No Data Available

Interacting Proteins for SNORD115-48 Gene

Gene Ontology (GO) - Biological Process for SNORD115-48 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD115-48 Gene

Drugs & Compounds for SNORD115-48 Gene

No Compound Related Data Available

Transcripts for SNORD115-48 Gene

mRNA/cDNA for SNORD115-48 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD115-48 Gene

No ASD Table

Relevant External Links for SNORD115-48 Gene

GeneLoc Exon Structure for
SNORD115-48
ECgene alternative splicing isoforms for
SNORD115-48

Expression for SNORD115-48 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD115-48 Gene

Orthologs for SNORD115-48 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SNORD115-48 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD115 35
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25499 35
  • 71 (a)
ManyToMany
Gm22496 35
  • 59 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia SNORD115 35
  • 68 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia SNORD115 35
  • 66 (a)
ManyToMany
Species where no ortholog for SNORD115-48 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD115-48 Gene

ENSEMBL:
Gene Tree for SNORD115-48 (if available)
TreeFam:
Gene Tree for SNORD115-48 (if available)

Paralogs for SNORD115-48 Gene

No data available for Paralogs for SNORD115-48 Gene

Variants for SNORD115-48 Gene

Sequence variations from dbSNP and Humsavar for SNORD115-48 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000200444 -- 25,270,273(+) ATTGA(C/T)TGACA downstream-variant-500B
rs1000536907 -- 25,269,167(+) ACTCA(C/T)AACTG upstream-variant-2KB
rs1003106846 -- 25,268,264(+) TGTGT(A/G)AGCCA upstream-variant-2KB
rs1004391699 -- 25,269,157(+) TTGAG(A/G)CACTA upstream-variant-2KB
rs1004868168 -- 25,268,806(+) GGTGT(A/G)TCATT downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORD115-48 Gene

Variant ID Type Subtype PubMed ID
esv33464 CNV gain 17666407

Relevant External Links for SNORD115-48 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD115-48

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD115-48 Gene

Disorders for SNORD115-48 Gene

Relevant External Links for SNORD115-48

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORD115-48

No disorders were found for SNORD115-48 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD115-48 Gene

Publications for SNORD115-48 Gene

  1. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. (PMID: 11726556) Runte M. … Buiting K. (Hum. Mol. Genet. 2001) 2 3 64
  2. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. (PMID: 11106375) CavaillAc J. … HA1ttenhofer A. (Proc. Natl. Acad. Sci. U.S.A. 2000) 2 3 64
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  4. The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C. (PMID: 16357227) Kishore S. … Stamm S. (Science 2006) 3 64
  5. Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome. (PMID: 15565282) Runte M. … Buiting K. (Hum. Genet. 2005) 3 64

Products for SNORD115-48 Gene

Sources for SNORD115-48 Gene

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