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Aliases for SNORD115-21 Gene

Subcategory (RNA class) for SNORD115-21 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD115-21 Gene

  • Small Nucleolar RNA, C/D Box 115-21 2 3
  • HBII-52-21 3

External Ids for SNORD115-21 Gene

ORGUL Members for SNORD115-21 Gene

Previous GeneCards Identifiers for SNORD115-21 Gene

  • GC15U900703
  • GC15P023473
  • GC15P023549
  • GC15P023646
  • GC15P025453
  • GC15P003577

Summaries for SNORD115-21 Gene

GeneCards Summary for SNORD115-21 Gene

SNORD115-21 (Small Nucleolar RNA, C/D Box 115-21) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD115-21 Gene

Genomics for SNORD115-21 Gene

Regulatory Elements for SNORD115-21 Gene

Transcription factor binding sites by QIAGEN in the SNORD115-21 gene promoter:

Genomic Location for SNORD115-21 Gene

Start:
25,208,083 bp from pter
End:
25,208,163 bp from pter
Size:
81 bases
Orientation:
Plus strand

Genomic View for SNORD115-21 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORD115-21 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD115-21 Gene

Proteins for SNORD115-21 Gene

Post-translational modifications for SNORD115-21 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD115-21 Gene

Domains for SNORD115-21 Gene

Gene Families for SNORD115-21 Gene

HGNC:
  • SNORD :ncRNAs / Small nucleolar RNAs : C/D box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD115-21: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD115-21 Gene

Function for SNORD115-21 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORD115-21 Gene

Localization for SNORD115-21 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD115-21 Gene

Pathways for SNORD115-21 Gene

SuperPathways for SNORD115-21 Gene

No Data Available

Interacting Proteins for SNORD115-21 Gene

Gene Ontology (GO) - Biological Process for SNORD115-21 Gene

None

No data available for Pathways by source for SNORD115-21 Gene

Transcripts for SNORD115-21 Gene

mRNA/cDNA for SNORD115-21 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORD115-21
    • Block miRNA regulation of SNORD115-21 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORD115-21

    Primer Products

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for SNORD115-21 Gene

    No ASD Table

    Relevant External Links for SNORD115-21 Gene

    GeneLoc Exon Structure for
    SNORD115-21
    ECgene alternative splicing isoforms for
    SNORD115-21

    Expression for SNORD115-21 Gene

    mRNA expression in normal human tissues for SNORD115-21 Gene

    genes like me logo Genes that share expressions with SNORD115-21: view

    In Situ Assay Products

    No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SNORD115-21 Gene

    Orthologs for SNORD115-21 Gene

    This gene was present in the common ancestor of human and chimp.

    Orthologs for SNORD115-21 Gene

    Organism Taxonomy Gene Similarity Type Details
    chimpanzee
    (Pan troglodytes)
    Mammalia SNORD115 36
    • 98 (a)
    OneToOne
    Species with no ortholog for SNORD115-21:
    • A. gosspyii yeast (Ashbya gossypii)
    • Actinobacteria (Mycobacterium tuberculosis)
    • African clawed frog (Xenopus laevis)
    • African malaria mosquito (Anopheles gambiae)
    • Alicante grape (Vitis vinifera)
    • alpha proteobacteria (Wolbachia pipientis)
    • amoeba (Dictyostelium discoideum)
    • Archea (Pyrococcus horikoshii)
    • baker's yeast (Saccharomyces cerevisiae)
    • barley (Hordeum vulgare)
    • beta proteobacteria (Neisseria meningitidis)
    • bread mold (Neurospora crassa)
    • chicken (Gallus gallus)
    • Chromalveolata (Phytophthora infestans)
    • common water flea (Daphnia pulex)
    • corn (Zea mays)
    • cow (Bos Taurus)
    • dog (Canis familiaris)
    • E. coli (Escherichia coli)
    • filamentous fungi (Aspergillus nidulans)
    • Firmicute bacteria (Streptococcus pneumoniae)
    • fission yeast (Schizosaccharomyces pombe)
    • fruit fly (Drosophila melanogaster)
    • green algae (Chlamydomonas reinhardtii)
    • honey bee (Apis mellifera)
    • K. lactis yeast (Kluyveromyces lactis)
    • lizard (Anolis carolinensis)
    • loblloly pine (Pinus taeda)
    • malaria parasite (Plasmodium falciparum)
    • medicago trunc (Medicago Truncatula)
    • moss (Physcomitrella patens)
    • mouse (Mus musculus)
    • oppossum (Monodelphis domestica)
    • orangutan (Pongo pygmaeus)
    • pig (Sus scrofa)
    • platypus (Ornithorhynchus anatinus)
    • rainbow trout (Oncorhynchus mykiss)
    • rat (Rattus norvegicus)
    • rice (Oryza sativa)
    • rice blast fungus (Magnaporthe grisea)
    • schistosome parasite (Schistosoma mansoni)
    • sea anemone (Nematostella vectensis)
    • sea squirt (Ciona intestinalis)
    • sea squirt (Ciona savignyi)
    • sea urchin (Strongylocentrotus purpuratus)
    • sorghum (Sorghum bicolor)
    • soybean (Glycine max)
    • stem rust fungus (Puccinia graminis)
    • sugarcane (Saccharum officinarum)
    • thale cress (Arabidopsis thaliana)
    • tomato (Lycopersicon esculentum)
    • toxoplasmosis (Toxoplasma gondii)
    • Trichoplax (Trichoplax adhaerens)
    • tropical clawed frog (Silurana tropicalis)
    • wheat (Triticum aestivum)
    • worm (Caenorhabditis elegans)
    • zebrafish (Danio rerio)

    Evolution for SNORD115-21 Gene

    ENSEMBL:
    Gene Tree for SNORD115-21 (if available)
    TreeFam:
    Gene Tree for SNORD115-21 (if available)

    Paralogs for SNORD115-21 Gene

    No data available for Paralogs for SNORD115-21 Gene

    Variants for SNORD115-21 Gene

    Sequence variations from dbSNP and Humsavar for SNORD115-21 Gene

    SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
    rs2714755 -- 25,207,565(+) CGGGC(A/C)AGCCT upstream-variant-2KB
    rs2739781 -- 25,207,051(+) TTGAG(C/T)AATGG upstream-variant-2KB
    rs6576414 -- 25,207,867(+) AGGCC(C/T)TACTT upstream-variant-2KB
    rs7182251 -- 25,207,907(+) AGCTC(A/G)GAGGA upstream-variant-2KB
    rs7182818 -- 25,207,549(+) AGCAG(A/C/T)GCGTG upstream-variant-2KB

    Structural Variations from Database of Genomic Variants (DGV) for SNORD115-21 Gene

    Variant ID Type Subtype PubMed ID
    nsv903722 CNV Gain+Loss 21882294
    esv33464 CNV Gain 17666407
    esv25915 CNV Gain+Loss 19812545
    nsv517360 CNV Gain+Loss 19592680
    dgv2286n71 CNV Loss 21882294
    esv2749458 CNV Deletion 23290073
    esv2658559 CNV Deletion 23128226
    esv2678119 CNV Deletion 23128226
    esv2749459 CNV Deletion 23290073
    esv2749460 CNV Deletion 23290073
    esv2444453 CNV Deletion 19546169
    esv2430173 CNV Loss 19546169
    esv2021287 CNV Deletion 18987734
    esv2667590 CNV Deletion 23128226
    nsv1467 CNV Loss 18451855
    esv2599789 CNV Deletion 19546169
    esv2332005 CNV Deletion 18987734
    esv2673872 CNV Deletion 23128226
    esv2483086 CNV Loss 19546169

    Relevant External Links for SNORD115-21 Gene

    HapMap Linkage Disequilibrium report
    SNORD115-21

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNORD115-21 Gene

    Disorders for SNORD115-21 Gene

    No disorders were found for SNORD115-21 Gene.

    No data available for UniProtKB/Swiss-Prot for SNORD115-21 Gene

    Publications for SNORD115-21 Gene

    1. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. (PMID: 11106375) CavaillAc J. … HA1ttenhofer A. (Proc. Natl. Acad. Sci. U.S.A. 2000) 2 3
    2. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. (PMID: 11726556) Runte M. … Buiting K. (Hum. Mol. Genet. 2001) 2 3
    3. Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. (PMID: 12045206) CavaillAc J. … Bachellerie J.P. (Hum. Mol. Genet. 2002) 3
    4. Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome. (PMID: 15565282) Runte M. … Buiting K. (Hum. Genet. 2005) 3
    5. ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs. (PMID: 15939761) Vitali P. … Huttenhofer A. (J. Cell Biol. 2005) 3

    Products for SNORD115-21 Gene

    Sources for SNORD115-21 Gene

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