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Aliases for SNORD115-1 Gene

Subcategory (RNA class) for SNORD115-1 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORD115-1 Gene

  • Small Nucleolar RNA, C/D Box 115-1 2 3 5
  • HBII-52-1 SnoRNA 3
  • HBII-52-1 3
  • RNHBII52 3

External Ids for SNORD115-1 Gene

ORGUL Members for SNORD115-1 Gene

Previous GeneCards Identifiers for SNORD115-1 Gene

  • GC15P023270
  • GC15P023343
  • GC15P023411
  • GC15P023453
  • GC15P023533
  • GC15P023631
  • GC15P025416
  • GC15P003552
  • GC15P025581
  • GC15P025697
  • GC15P025171
  • GC15P025173
  • GC15P025399
  • GC15P025554
  • GC15P025638
  • GC15P025724

Summaries for SNORD115-1 Gene

Entrez Gene Summary for SNORD115-1 Gene

  • This gene encodes a small nucleolar RNA (snoRNA) that is found clustered with dozens of other similar snoRNAs on chromosome 15. These genes are found mostly within introns of the IC-SNURF-SNRPN transcript, which is paternally imprinted and from the Prader-Willi/Angelman syndrome (PWS) region. This gene has been designated as copy 1 of the cluster and may be involved in the regulation of RNA editing and/or alternative splicing of the serotonin receptor 2C (HTR2C) transcript. This gene is not thought to play a major role in PWS. [provided by RefSeq, Jul 2008]

GeneCards Summary for SNORD115-1 Gene

SNORD115-1 (Small Nucleolar RNA, C/D Box 115-1) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD115-1 include Angelman Syndrome.

Additional gene information for SNORD115-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD115-1 Gene

Genomics for SNORD115-1 Gene

GeneHancer (GH) Regulatory Elements for SNORD115-1 Gene

Promoters and enhancers for SNORD115-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I025134 Enhancer 0.4 ENCODE 11.4 -36.0 -35954 0.2 CTCF POLR2A PWAR1 SNORD116-29 SNORD116-30 SNHG14 ENSG00000212428 SNORD115-1 SNORD115-2 SNORD116-27 SNORD116-25 SNORD116-26
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORD115-1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORD115-1 gene promoter:

Genomic Locations for SNORD115-1 Gene

Genomic Locations for SNORD115-1 Gene
chr15:25,170,723-25,170,804
(GRCh38/hg38)
Size:
82 bases
Orientation:
Plus strand
chr15:25,415,870-25,415,951
(GRCh37/hg19)

Genomic View for SNORD115-1 Gene

Genes around SNORD115-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD115-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD115-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD115-1 Gene

Proteins for SNORD115-1 Gene

Post-translational modifications for SNORD115-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD115-1 Gene

Domains & Families for SNORD115-1 Gene

Gene Families for SNORD115-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD115-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD115-1 Gene

Function for SNORD115-1 Gene

Human Phenotype Ontology for SNORD115-1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD115-1 Gene

Localization for SNORD115-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORD115-1 Gene

Pathways & Interactions for SNORD115-1 Gene

SuperPathways for SNORD115-1 Gene

No Data Available

Interacting Proteins for SNORD115-1 Gene

Gene Ontology (GO) - Biological Process for SNORD115-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD115-1 Gene

Drugs & Compounds for SNORD115-1 Gene

No Compound Related Data Available

Transcripts for SNORD115-1 Gene

mRNA/cDNA for SNORD115-1 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD115-1 Gene

No ASD Table

Relevant External Links for SNORD115-1 Gene

GeneLoc Exon Structure for
SNORD115-1
ECgene alternative splicing isoforms for
SNORD115-1

Expression for SNORD115-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD115-1 Gene

genes like me logo Genes that share expression patterns with SNORD115-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD115-1 Gene

Orthologs for SNORD115-1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SNORD115-1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD115 34
  • 99 (a)
OneToOne
Species where no ortholog for SNORD115-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD115-1 Gene

ENSEMBL:
Gene Tree for SNORD115-1 (if available)
TreeFam:
Gene Tree for SNORD115-1 (if available)

Paralogs for SNORD115-1 Gene

No data available for Paralogs for SNORD115-1 Gene

Variants for SNORD115-1 Gene

Sequence variations from dbSNP and Humsavar for SNORD115-1 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000829968 -- 25,170,199(+) C/G upstream_transcript_variant
rs1001284856 -- 25,170,615(+) G/T upstream_transcript_variant
rs1001332045 -- 25,170,673(+) C/A upstream_transcript_variant
rs1002758670 -- 25,170,014(+) A/G upstream_transcript_variant
rs1003726952 -- 25,169,716(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORD115-1 Gene

Variant ID Type Subtype PubMed ID
dgv2478n100 CNV gain 25217958
dgv2479n100 CNV gain 25217958
dgv2480n100 CNV loss 25217958
dgv2481n100 CNV gain 25217958
dgv2482n100 CNV gain 25217958
dgv2483n100 CNV gain+loss 25217958
esv2761832 CNV gain+loss 21179565
nsv456731 CNV loss 19166990
nsv568550 CNV loss 21841781
nsv952576 CNV deletion 24416366

Additional Variant Information for SNORD115-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD115-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD115-1 Gene

Disorders for SNORD115-1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORD115-1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
angelman syndrome
  • as
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORD115-1

genes like me logo Genes that share disorders with SNORD115-1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD115-1 Gene

Publications for SNORD115-1 Gene

  1. Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome. (PMID: 15565282) Runte M … Buiting K (Human genetics 2005) 3 22 58
  2. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. (PMID: 11726556) Runte M … Buiting K (Human molecular genetics 2001) 2 3 58
  3. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. (PMID: 11106375) Cavaillé J … Hüttenhofer A (Proceedings of the National Academy of Sciences of the United States of America 2000) 2 3 58
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  5. Positive selection and gene conversion drive the evolution of a brain-expressed snoRNAs cluster. (PMID: 19651851) Ogorelkova M … Estivill X (Molecular biology and evolution 2009) 22 58

Products for SNORD115-1 Gene

Sources for SNORD115-1 Gene

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