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Aliases for SNORD115-1 Gene

Subcategory (RNA class) for SNORD115-1 Gene


Quality Score for this RNA gene is


Aliases for SNORD115-1 Gene

  • Small Nucleolar RNA, C/D Box 115-1 2 3
  • HBII-52-1 SnoRNA 3
  • HBII-52-1 3
  • RNHBII52 3

External Ids for SNORD115-1 Gene

ORGUL Members for SNORD115-1 Gene

Previous GeneCards Identifiers for SNORD115-1 Gene

  • GC15P023270
  • GC15P023343
  • GC15P023411
  • GC15P023453
  • GC15P023533
  • GC15P023631
  • GC15P025416
  • GC15P003552
  • GC15P025581
  • GC15P025697

Summaries for SNORD115-1 Gene

Entrez Gene Summary for SNORD115-1 Gene

  • This gene encodes a small nucleolar RNA (snoRNA) that is found clustered with dozens of other similar snoRNAs on chromosome 15. These genes are found mostly within introns of the IC-SNURF-SNRPN transcript, which is paternally imprinted and from the Prader-Willi/Angelman syndrome (PWS) region. This gene has been designated as copy 1 of the cluster and may be involved in the regulation of RNA editing and/or alternative splicing of the serotonin receptor 2C (HTR2C) transcript. This gene is not thought to play a major role in PWS. [provided by RefSeq, Jul 2008]

GeneCards Summary for SNORD115-1 Gene

SNORD115-1 (Small Nucleolar RNA, C/D Box 115-1) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORD115-1 include angelman syndrome.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORD115-1 Gene

Genomics for SNORD115-1 Gene

Regulatory Elements for SNORD115-1 Gene

Genomic Location for SNORD115-1 Gene

25,170,723 bp from pter
25,170,804 bp from pter
82 bases
Plus strand

Genomic View for SNORD115-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORD115-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD115-1 Gene

Proteins for SNORD115-1 Gene

Post-translational modifications for SNORD115-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD115-1 Gene

Domains & Families for SNORD115-1 Gene

Gene Families for SNORD115-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD115-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD115-1 Gene

Function for SNORD115-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD115-1 Gene

Localization for SNORD115-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD115-1 Gene

Pathways & Interactions for SNORD115-1 Gene

SuperPathways for SNORD115-1 Gene

No Data Available

Interacting Proteins for SNORD115-1 Gene

Gene Ontology (GO) - Biological Process for SNORD115-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORD115-1 Gene

Drugs & Compounds for SNORD115-1 Gene

No Compound Related Data Available

Transcripts for SNORD115-1 Gene

mRNA/cDNA for SNORD115-1 Gene

(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD115-1 Gene

No ASD Table

Relevant External Links for SNORD115-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORD115-1 Gene

mRNA expression in normal human tissues for SNORD115-1 Gene

genes like me logo Genes that share expression patterns with SNORD115-1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SNORD115-1 Gene

Orthologs for SNORD115-1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for SNORD115-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORD115 36
  • 99 (a)
Species with no ortholog for SNORD115-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD115-1 Gene

Gene Tree for SNORD115-1 (if available)
Gene Tree for SNORD115-1 (if available)

Paralogs for SNORD115-1 Gene

No data available for Paralogs for SNORD115-1 Gene

Variants for SNORD115-1 Gene

Sequence variations from dbSNP and Humsavar for SNORD115-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1883008 -- 25,170,547(+) ACCAT(A/G)GAGGA upstream-variant-2KB
rs2714732 -- 25,169,290(+) TCTGT(A/G)TGTTA upstream-variant-2KB
rs2714733 -- 25,170,046(+) GTGTG(A/G)TTGGG upstream-variant-2KB
rs2714734 -- 25,170,612(+) CCCCC(A/G)GTGCG upstream-variant-2KB
rs2739832 -- 25,169,298(+) TTATG(A/G)GGGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORD115-1 Gene

Variant ID Type Subtype PubMed ID
nsv903721 CNV Gain 21882294
nsv456731 CNV Loss 19166990
nsv903722 CNV Gain+Loss 21882294

Relevant External Links for SNORD115-1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD115-1 Gene

Disorders for SNORD115-1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORD115-1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
angelman syndrome
  • happy puppet syndrome
- elite association

Relevant External Links for SNORD115-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SNORD115-1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORD115-1 Gene

Publications for SNORD115-1 Gene

  1. Positive selection and gene conversion drive the evolution of a brain-expressed snoRNAs cluster. (PMID: 19651851) Ogorelkova M. … Estivill X. (Mol. Biol. Evol. 2009) 23 67
  2. Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome. (PMID: 15565282) Runte M. … Buiting K. (Hum. Genet. 2005) 23 67
  3. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. (PMID: 11726556) Runte M. … Buiting K. (Hum. Mol. Genet. 2001) 2 67
  4. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. (PMID: 11106375) CavaillAc J. … HA1ttenhofer A. (Proc. Natl. Acad. Sci. U.S.A. 2000) 2 67
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 67

Products for SNORD115-1 Gene

Sources for SNORD115-1 Gene

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