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Aliases for SNORD114-27 Gene

Subcategory (RNA class) for SNORD114-27 Gene


Quality Score for this RNA gene is


Aliases for SNORD114-27 Gene

  • Small Nucleolar RNA, C/D Box 114-27 2 3
  • 14q(II-27) 3

External Ids for SNORD114-27 Gene

ORGUL Members for SNORD114-27 Gene

Previous GeneCards Identifiers for SNORD114-27 Gene

  • GC14U900727
  • GC14P100551
  • GC14P100891
  • GC14P100976
  • GC14P101454
  • GC14P081638

Summaries for SNORD114-27 Gene

GeneCards Summary for SNORD114-27 Gene

SNORD114-27 (Small Nucleolar RNA, C/D Box 114-27) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORD114-27 Gene - the ORGUL cluster for this gene includes several descriptions:

  • C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.

  • Small nucleolar RNA SNORD113/SNORD114 family: The imprinted human domain at 14q32 contains two clusters of tandemly repeated small nucleolar RNAs named 14q(I) and 14q(II) snoRNAs. These two clusters are named SNORD113 and SNORD114 respectively in the HGNC approved gene symbol nomenclature. The snoRNAs found in both clusters are clearly related and are represented here by a single family. These snoRNAs are intron encoded and are processed from the tissue-specific non-coding human MEG8 RNA, which lies downstream of the imprinted genes DLK1 and GTL2. snoRNAs 14q(I) and 14q(II) differ from previously identified C/D box snoRNAs in their expression profiles and lack of complementarity to rRNA and snRNA. Homologues of these snoRNAs are found in the imprinted non-coding mouse transcript Rian, and in the rat non-coding Bsr (brain-specific repetitive) RNA.

View fRNAdb secondary structures for SNORD114-27

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD114-27 Gene

Genomics for SNORD114-27 Gene

Regulatory Elements for SNORD114-27 Gene

Transcription factor binding sites by QIAGEN in the SNORD114-27 gene promoter:

Genomic Location for SNORD114-27 Gene

100,988,161 bp from pter
100,988,230 bp from pter
70 bases
Plus strand

Genomic View for SNORD114-27 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORD114-27 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD114-27 Gene

ORGUL Member Location for SNORD114-27 Gene

ORGUL Member Location for SNORD114-27 gene

Proteins for SNORD114-27 Gene

Post-translational modifications for SNORD114-27 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD114-27 Gene

Domains for SNORD114-27 Gene

Gene Families for SNORD114-27 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD114-27: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD114-27 Gene

Function for SNORD114-27 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORD114-27 Gene

Localization for SNORD114-27 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD114-27 Gene

Pathways for SNORD114-27 Gene

SuperPathways for SNORD114-27 Gene

No Data Available

Interacting Proteins for SNORD114-27 Gene

Gene Ontology (GO) - Biological Process for SNORD114-27 Gene


No data available for Pathways by source for SNORD114-27 Gene

Transcripts for SNORD114-27 Gene

fRNAdb Secondary structures for SNORD114-27 Gene

  • FR173790

mRNA/cDNA for SNORD114-27 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD114-27 Gene

No ASD Table

Relevant External Links for SNORD114-27 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORD114-27 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SNORD114-27 Gene

Orthologs for SNORD114-27 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SNORD114-27 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia SNORD113 36
  • 82 (a)
(Mus musculus)
Mammalia Gm23347 36
  • 54 (a)
(Pan troglodytes)
Mammalia SNORD113 36
  • 99 (a)
Species with no ortholog for SNORD114-27:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORD114-27 Gene

Gene Tree for SNORD114-27 (if available)
Gene Tree for SNORD114-27 (if available)

Paralogs for SNORD114-27 Gene

No data available for Paralogs for SNORD114-27 Gene

Variants for SNORD114-27 Gene

Relevant External Links for SNORD114-27 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SNORD114-27 Gene

Disorders for SNORD114-27 Gene

No disorders were found for SNORD114-27 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SNORD114-27 Gene

Publications for SNORD114-27 Gene

  1. Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. (PMID: 12045206) CavaillAc J. … Bachellerie J.P. (Hum. Mol. Genet. 2002) 2 3
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3

Products for SNORD114-27 Gene

Sources for SNORD114-27 Gene

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