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Aliases for SNORD111 Gene

Subcategory (RNA class) for SNORD111 Gene

snoRNA

Quality Score for this RNA gene is

7

Aliases for SNORD111 Gene

  • Small Nucleolar RNA, C/D Box 111 2 3 5
  • HBII-82 3

External Ids for SNORD111 Gene

ORGUL Members for SNORD111 Gene

Previous GeneCards Identifiers for SNORD111 Gene

  • GC16U900064
  • GC16P069130
  • GC16P056403

Summaries for SNORD111 Gene

GeneCards Summary for SNORD111 Gene

SNORD111 (Small Nucleolar RNA, C/D Box 111) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORD111 Gene - the ORGUL cluster for this gene includes several descriptions:

  • C_D_box_snoRNA: Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.

  • Small Nucleolar RNA SNORD111: The members of this family belong to the C/D class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs [1]. HBII-82 (SNORD111) is predicted to guide the 2'O-ribose methylation of 28S rRNA G3923 [3].

View fRNAdb secondary structures for SNORD111

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORD111 Gene

Genomics for SNORD111 Gene

Regulatory Elements for SNORD111 Gene

Enhancers for SNORD111 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G070744 2 FANTOM5 Ensembl ENCODE dbSUPER 9.2 +210.7 210676 7.4 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 FEZF1 ZNF2 LOC400541 PDPR VAC14 LOC100506083 ENSG00000247324 SNORD111 MTSS1L VAC14-AS1 FUK COG4
GH16G070589 1.2 Ensembl ENCODE dbSUPER 11.6 +53.1 53078 4.5 BCOR KLF1 JUN ZMYM3 ZNF384 RAD21 FOS ZNF362 RNF2 HLF PDXDC2P-NPIPB14P PDXDC2P COG4 SNORD111 AARS VAC14-AS1 DDX19B LOC100506083 NPIPB14P EXOSC6
GH16G070767 1.3 ENCODE dbSUPER 10.1 +230.2 230151 1.4 HDGF ATF1 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF48 SLC30A9 ELK1 SF3B3 EXOSC6 PDPR VAC14 COG4 PDXDC2P-NPIPB14P PDXDC2P SNORD111 AARS DDX19B
GH16G070560 0.8 dbSUPER 12.4 +24.4 24414 4.4 ZNF146 NFIB SIN3A CEBPG ZNF121 CTBP1 GATA3 ZFHX2 POLR2A RCOR1 PDXDC2P SNORD111 SNORD111B COG4 SF3B3 VAC14-AS1 AARS DDX19B LOC100506083 IL34
GH16G070567 0.8 ENCODE dbSUPER 12.1 +31.1 31123 2.4 ZNF263 CTCF PAF1 SMARCA4 POLR2A SCRT2 PDXDC2P SNORD111 AARS VAC14-AS1 EXOSC6 LOC100506083 FUK IL34
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORD111 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORD111 Gene

Chromosome:
16
Start:
70,538,005 bp from pter
End:
70,538,098 bp from pter
Size:
94 bases
Orientation:
Plus strand

Genomic View for SNORD111 Gene

Genes around SNORD111 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORD111 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORD111 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORD111 Gene

ORGUL Member Location for SNORD111 Gene

ORGUL Member Location for SNORD111 gene

Proteins for SNORD111 Gene

Post-translational modifications for SNORD111 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORD111 Gene

Domains & Families for SNORD111 Gene

Gene Families for SNORD111 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORD111: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORD111 Gene

Function for SNORD111 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORD111 Gene

Localization for SNORD111 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORD111 Gene

Pathways & Interactions for SNORD111 Gene

SuperPathways for SNORD111 Gene

No Data Available

Interacting Proteins for SNORD111 Gene

Gene Ontology (GO) - Biological Process for SNORD111 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORD111 Gene

Transcripts for SNORD111 Gene

fRNAdb Secondary structures for SNORD111 Gene

  • RF00611;SNORD111;ABBA01010656.1/6782-6875

mRNA/cDNA for SNORD111 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORD111 Gene

No ASD Table

Relevant External Links for SNORD111 Gene

GeneLoc Exon Structure for
SNORD111
ECgene alternative splicing isoforms for
SNORD111

Expression for SNORD111 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORD111 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORD111 Gene:

SNORD111
genes like me logo Genes that share expression patterns with SNORD111: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORD111 Gene

Orthologs for SNORD111 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORD111 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORD111 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORD111 35
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snord111 35
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORD111 35
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORD111 35
  • 71 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORD111 35
  • 70 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORD111 35
  • 68 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORD111 35
  • 64 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORD111 35 35 35 35 35
  • 68 (a)
ManyToMany
Species where no ortholog for SNORD111 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORD111 Gene

ENSEMBL:
Gene Tree for SNORD111 (if available)
TreeFam:
Gene Tree for SNORD111 (if available)

Paralogs for SNORD111 Gene

No data available for Paralogs for SNORD111 Gene

Variants for SNORD111 Gene

Sequence variations from dbSNP and Humsavar for SNORD111 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000144400 -- 70,537,207(+) TATAA(A/G)TGATA intron-variant, upstream-variant-2KB
rs1000766648 -- 70,537,968(+) ATTTG(A/G)TGTAG intron-variant, upstream-variant-2KB
rs1002803562 -- 70,536,753(+) TCCCA(A/G)GGTGC intron-variant, upstream-variant-2KB
rs1003940536 -- 70,536,957(+) AGGCA(C/T)CTGTT intron-variant, upstream-variant-2KB
rs1004275908 -- 70,537,124(+) CTTAT(A/G)GTCTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORD111 Gene

Variant ID Type Subtype PubMed ID
esv3892881 CNV gain 25118596
esv3892883 CNV gain 25118596
nsv7285 OTHER inversion 18451855

Relevant External Links for SNORD111 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORD111

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORD111 Gene

Disorders for SNORD111 Gene

Relevant External Links for SNORD111

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORD111

No disorders were found for SNORD111 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORD111 Gene

Publications for SNORD111 Gene

  1. RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse. (PMID: 11387227) HA1ttenhofer A. … Brosius J. (EMBO J. 2001) 1 2 3 64
  2. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  3. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1
  4. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang K.C. … Mattick J.S. (Nucleic Acids Res. 2005) 1
  5. Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro. (PMID: 12215523) Galardi S. … Bozzoni I. (Mol. Cell. Biol. 2002) 1

Products for SNORD111 Gene

Sources for SNORD111 Gene

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