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Aliases for SNORA80B Gene

Subcategory (RNA class) for SNORA80B Gene


Quality Score for this RNA gene is


Aliases for SNORA80B Gene

  • Small Nucleolar RNA, H/ACA Box 80B 2 3 5
  • ACA67B 3

External Ids for SNORA80B Gene

Previous GeneCards Identifiers for SNORA80B Gene

  • GC00U922697
  • GC02M010586

Summaries for SNORA80B Gene

GeneCards Summary for SNORA80B Gene

SNORA80B (Small Nucleolar RNA, H/ACA Box 80B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA80B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA42/SNORA80 family: The members of this family belong to the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. Human ACA42 (SNORA42) was cloned from HeLa cells by immunoprecipitation with anti-GAR1 antibody [1]. Its is predicted to guide the pseudouridylation of residues U109 and U572 of 18S rRNA [3]. ACA42 shares the same host gene with ACA26, ACA46, ACA50 [1]. This family also includes mammalian snoRNA ACA67 (SNORA80) which was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis [2]. ACA67 is proposed to guide the pseudouridylation of the same 18S rRNA residues as ACA42 [3].

View fRNAdb secondary structures for SNORA80B

Additional gene information for SNORA80B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA80B Gene

Genomics for SNORA80B Gene

GeneHancer (GH) Regulatory Elements for SNORA80B Gene

Promoters and enhancers for SNORA80B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I010446 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 -1.9 -1906 5 HDGF FOXA2 SMAD1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ENSG00000257135 GC02M010446 LOC101929715 ODC1 SNORA80B TAF1B
GH02I010445 Enhancer 0.7 ENCODE 550.8 +1.3 1253 1 PKNOX1 IRF4 ATF7 ZSCAN29 IKZF2 RUNX3 ZNF687 JUNB TRIM22 DPF2 GC02M010446 SNORA80B LOC101929691 HPCAL1 ODC1 PIR41580
GH02I010119 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.8 +324.4 324415 6.1 ZFP64 DMAP1 YY1 E2F8 ZNF143 SP3 NFYC MEF2D ZNF610 GLIS1 RRM2 ENSG00000284681 LOC101929882 ENSG00000233502 CYS1 TAF1B SNORA80B HPCAL1 LOC101929691 ODC1
GH02I010327 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.4 +116.1 116140 6.1 HDGF PKNOX1 SMAD1 ARNT ZFP64 SIN3A DMAP1 ZNF121 ZNF766 ATF7 HPCAL1 LOC101929691 SNORA80B TAF1B PIR41580
GH02I010403 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +38.8 38824 8.3 HDGF PKNOX1 ARNT ARID4B NEUROD1 SIN3A YBX1 DMAP1 ZNF2 IRF4 HPCAL1 LOC101929882 LOC101929691 SNORA80B PIR41580
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA80B on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA80B Gene

Genomic Locations for SNORA80B Gene
136 bases
Minus strand

Genomic View for SNORA80B Gene

Genes around SNORA80B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA80B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA80B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA80B Gene

ORGUL Member Location for SNORA80B Gene

ORGUL Member Location for SNORA80B gene

Proteins for SNORA80B Gene

Post-translational modifications for SNORA80B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA80B Gene

Domains & Families for SNORA80B Gene

Gene Families for SNORA80B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA80B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA80B Gene

Function for SNORA80B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA80B Gene

Localization for SNORA80B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA80B Gene

Pathways & Interactions for SNORA80B Gene

SuperPathways for SNORA80B Gene

No Data Available

Interacting Proteins for SNORA80B Gene

Gene Ontology (GO) - Biological Process for SNORA80B Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA80B Gene

Drugs & Compounds for SNORA80B Gene

No Compound Related Data Available

Transcripts for SNORA80B Gene

fRNAdb Secondary structures for SNORA80B Gene

  • RF00406;SNORA42;DAAB011010585.1/827-925

mRNA/cDNA for SNORA80B Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA80B Gene

Small nucleolar RNA, H/ACA box 80B:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA80B Gene

No ASD Table

Relevant External Links for SNORA80B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA80B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA80B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA80B Gene:


SOURCE GeneReport for Unigene cluster for SNORA80B Gene:

genes like me logo Genes that share expression patterns with SNORA80B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA80B Gene

Orthologs for SNORA80B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA80B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA42 34
  • 100 (a)
(Canis familiaris)
Mammalia SNORA42 34
  • 92 (a)
(Bos Taurus)
Mammalia SNORA42 34
  • 89 (a)
(Mus musculus)
Mammalia Gm26394 34
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA42 34 34
  • 77 (a)
(Monodelphis domestica)
Mammalia SNORA42 34
  • 68 (a)
(Anolis carolinensis)
Reptilia SNORA42 34
  • 69 (a)
(Danio rerio)
Actinopterygii SNORA42 34
  • 59 (a)
Species where no ortholog for SNORA80B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA80B Gene

Gene Tree for SNORA80B (if available)
Gene Tree for SNORA80B (if available)

Paralogs for SNORA80B Gene

No data available for Paralogs for SNORA80B Gene

Variants for SNORA80B Gene

Sequence variations from dbSNP and Humsavar for SNORA80B Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs2302615 protective, Colonic adenoma recurrence, reduced risk of 10,448,012(-) C/T upstream_transcript_variant
rs1000101367 -- 10,447,155(-) T/C upstream_transcript_variant
rs1000614261 -- 10,446,692(-) C/G downstream_transcript_variant
rs1000665289 -- 10,446,949(-) C/T upstream_transcript_variant
rs1001108181 -- 10,448,171(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA80B Gene

Variant ID Type Subtype PubMed ID
nsv1007185 CNV gain 25217958
nsv580963 CNV gain 21841781

Additional Variant Information for SNORA80B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA80B Gene

Disorders for SNORA80B Gene

Additional Disease Information for SNORA80B

No disorders were found for SNORA80B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA80B Gene

Publications for SNORA80B Gene

  1. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  2. A computational screen for mammalian pseudouridylation guide H/ACA RNAs. (PMID: 16373490) Schattner P … Lowe TM (RNA (New York, N.Y.) 2006) 1
  3. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 1

Products for SNORA80B Gene

Sources for SNORA80B Gene

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