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Aliases for SNORA77 Gene

Subcategory (RNA class) for SNORA77 Gene

snoRNA

Quality Score for this RNA gene is

6.2

Aliases for SNORA77 Gene

  • Small Nucleolar RNA, H/ACA Box 77 2 3
  • ACA63 3

External Ids for SNORA77 Gene

ORGUL Members for SNORA77 Gene

Previous GeneCards Identifiers for SNORA77 Gene

  • GC01P201965
  • GC01P203698
  • GC01P174864

Summaries for SNORA77 Gene

GeneCards Summary for SNORA77 Gene

SNORA77 (Small Nucleolar RNA, H/ACA Box 77) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA77 Gene - the ORGUL cluster for this gene includes several descriptions:

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Small nucleolar RNA SNORA77: ACA63 (SNORA77) is a member of the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis [2]. ACA63 is proposed to guide the pseudouridylation of 18S rRNA U814 [2].

View fRNAdb secondary structures for SNORA77

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA77 Gene

Genomics for SNORA77 Gene

Regulatory Elements for SNORA77 Gene

Genomic Location for SNORA77 Gene

Start:
203,729,581 bp from pter
End:
203,729,705 bp from pter
Size:
125 bases
Orientation:
Plus strand

Genomic View for SNORA77 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA77 Gene

ORGUL Member Location for SNORA77 Gene

ORGUL Member Location for SNORA77 gene

Proteins for SNORA77 Gene

Post-translational modifications for SNORA77 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA77 Gene

Domains for SNORA77 Gene

Gene Families for SNORA77 Gene

HGNC:
  • SNORA :ncRNAs / Small nucleolar RNAs : H/ACA box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA77: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA77 Gene

Function for SNORA77 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA77 Gene

Localization for SNORA77 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA77 Gene

Pathways for SNORA77 Gene

SuperPathways for SNORA77 Gene

No Data Available

Interacting Proteins for SNORA77 Gene

Gene Ontology (GO) - Biological Process for SNORA77 Gene

None

No data available for Pathways by source for SNORA77 Gene

Transcripts for SNORA77 Gene

fRNAdb Secondary structures for SNORA77 Gene

  • FR322867

mRNA/cDNA for SNORA77 Gene

(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA77 Gene

Small nucleolar RNA, H/ACA box 77:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA77

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA77 Gene

No ASD Table

Relevant External Links for SNORA77 Gene

GeneLoc Exon Structure for
SNORA77
ECgene alternative splicing isoforms for
SNORA77

Expression for SNORA77 Gene

mRNA expression in normal human tissues for SNORA77 Gene

mRNA differential expression in normal tissues according to GTEx for SNORA77 Gene

This gene is overexpressed in Colon - Sigmoid (4.0).

SOURCE GeneReport for Unigene cluster for SNORA77 Gene Hs.676135

genes like me logo Genes that share expressions with SNORA77: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for SNORA77 Gene

Orthologs for SNORA77 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA77 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA77 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA77 36
  • 70 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SNORA77 36
  • 79 (a)
ManyToMany
SNORA77 36
  • 71 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm25777 36
  • 80 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA77 36
  • 60 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA77 36
  • 69 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA77 36
  • 61 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA77 36
  • 60 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA77 36
  • 54 (a)
OneToMany
Species with no ortholog for SNORA77:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA77 Gene

ENSEMBL:
Gene Tree for SNORA77 (if available)
TreeFam:
Gene Tree for SNORA77 (if available)

Paralogs for SNORA77 Gene

No data available for Paralogs for SNORA77 Gene

Variants for SNORA77 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA77 Gene

Variant ID Type Subtype PubMed ID
nsv467994 CNV Loss 19166990

Relevant External Links for SNORA77 Gene

HapMap Linkage Disequilibrium report
SNORA77

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for SNORA77 Gene

Disorders for SNORA77 Gene

No disorders were found for SNORA77 Gene.

No data available for UniProtKB/Swiss-Prot for SNORA77 Gene

Publications for SNORA77 Gene

  1. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3
  2. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3

Products for SNORA77 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA77
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA77
    • Block miRNA regulation of SNORA77 using miScript Target Protectors

    Sources for SNORA77 Gene

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