Subcategory (RNA class) for SNORA77 Gene
Quality Score for this RNA gene is
ORGUL Members for SNORA77 Gene
Previous GeneCards Identifiers for SNORA77 Gene
GeneCards Summary for SNORA77 Gene
SNORA77 (Small Nucleolar RNA, H/ACA Box 77) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORA77 Gene - the ORGUL cluster for this gene includes several descriptions:
ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.
nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.
Small nucleolar RNA SNORA77: ACA63 (SNORA77) is a member of the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines . This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis . ACA63 is proposed to guide the pseudouridylation of 18S rRNA U814 .