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Aliases for SNORA74B Gene

Subcategory (RNA class) for SNORA74B Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA74B Gene

  • Small Nucleolar RNA, H/ACA Box 74B 2 3 5
  • U19-2 SnoRNA 3
  • U19-2 3

External Ids for SNORA74B Gene

ORGUL Members for SNORA74B Gene

Previous GeneCards Identifiers for SNORA74B Gene

  • GC05P172381
  • GC05P167542
  • GC05P172447

Summaries for SNORA74B Gene

Entrez Gene Summary for SNORA74B Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA74B, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA74B Gene

SNORA74B (Small Nucleolar RNA, H/ACA Box 74B) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA74B Gene

Genomics for SNORA74B Gene

Regulatory Elements for SNORA74B Gene

Enhancers for SNORA74B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G173050 0.9 ENCODE 12.1 +30.6 30627 2.6 ATF1 PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 GATA2 ZNF143 DEK ZNF263 BNIP1 SNORA74B ENSG00000254328 ATP6V0E1 ENSG00000253172 ENSG00000207210 GC05M173053 GC05P173039
GH05G172978 0.7 Ensembl 11.4 -41.8 -41826 0.2 CTCF ESRRA PKNOX1 ZMYM3 RAD21 GATA3 ZNF316 ZNF366 ZNF143 SMC3 BNIP1 ENSG00000254295 RPL26L1 ENSG00000253172 ENSG00000207210 CREBRF SNORA74B ATP6V0E1 LOC285591
GH05G173069 0.7 Ensembl 11 +49.3 49275 0.4 MAZ ZBTB21 ZNF398 ZBTB8A ATF2 ZFP69B ZFHX2 ZBTB48 ZNF692 ZNF629 BNIP1 ENSG00000253172 ENSG00000254328 ATP6V0E1 SNORA74B LOC100268168 ENSG00000254295 RPL26L1 CREBRF CDC42P5
GH05G172968 0.5 Ensembl 10.4 -51.3 -51328 0.8 FOSL1 ATF3 SCRT2 CEBPB SPI1 ENSG00000207210 CREBRF SNORA74B LOC101928093 BNIP1 LOC285591 LOC100268168
GH05G173065 0.4 Ensembl 11.5 +44.8 44775 0.2 ZNF623 PRDM1 SNORA74B BNIP1 CREBRF CDC42P5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA74B on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA74B Gene

Chromosome:
5
Start:
173,020,726 bp from pter
End:
173,020,929 bp from pter
Size:
204 bases
Orientation:
Plus strand

Genomic View for SNORA74B Gene

Genes around SNORA74B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA74B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA74B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA74B Gene

Proteins for SNORA74B Gene

Post-translational modifications for SNORA74B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA74B Gene

Domains & Families for SNORA74B Gene

Gene Families for SNORA74B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA74B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA74B Gene

Function for SNORA74B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA74B Gene

Localization for SNORA74B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA74B Gene

Pathways & Interactions for SNORA74B Gene

SuperPathways for SNORA74B Gene

No Data Available

Interacting Proteins for SNORA74B Gene

Gene Ontology (GO) - Biological Process for SNORA74B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA74B Gene

Transcripts for SNORA74B Gene

mRNA/cDNA for SNORA74B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA74B Gene

No ASD Table

Relevant External Links for SNORA74B Gene

GeneLoc Exon Structure for
SNORA74B
ECgene alternative splicing isoforms for
SNORA74B

Expression for SNORA74B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA74B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA74B Gene:

SNORA74B

SOURCE GeneReport for Unigene cluster for SNORA74B Gene:

Hs.692720
genes like me logo Genes that share expression patterns with SNORA74B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA74B Gene

Orthologs for SNORA74B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA74B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA74 35
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23946 35
  • 80 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SNORA74 35
  • 78 (a)
OneToMany
cow
(Bos Taurus)
Mammalia SNORA74 35
  • 70 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA74 35
  • 63 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA74 35 35
  • 62 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA74 35
  • 61 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA74 35 35
  • 61 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA74 35
  • 55 (a)
OneToMany
Species where no ortholog for SNORA74B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA74B Gene

ENSEMBL:
Gene Tree for SNORA74B (if available)
TreeFam:
Gene Tree for SNORA74B (if available)

Paralogs for SNORA74B Gene

No data available for Paralogs for SNORA74B Gene

Variants for SNORA74B Gene

Sequence variations from dbSNP and Humsavar for SNORA74B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1004436151 -- 173,019,375(+) ACGGT(A/G)AAAAC intron-variant, upstream-variant-2KB
rs1004830244 -- 173,019,196(+) AGTGA(C/T)CCTTA intron-variant, upstream-variant-2KB
rs1011473336 -- 173,019,923(+) AAAAC(A/G)CTTTG intron-variant, upstream-variant-2KB
rs1012526709 -- 173,021,123(+) GCAGA(A/G)AGCAA intron-variant, downstream-variant-500B
rs1012899696 -- 173,019,154(+) TCTCA(C/T)TGTGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA74B Gene

Variant ID Type Subtype PubMed ID
nsv830555 CNV loss 17160897

Relevant External Links for SNORA74B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA74B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA74B Gene

Disorders for SNORA74B Gene

Relevant External Links for SNORA74B

Genetic Association Database (GAD)
SNORA74B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA74B

No disorders were found for SNORA74B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA74B Gene

Publications for SNORA74B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3 64
  2. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu A.D. … Qu L.H. (Nucleic Acids Res. 2005) 2 3 64
  3. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3 64
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  5. Genome-wide association study of PR interval. (PMID: 20062060) Pfeufer A. … Heckbert S.R. (Nat. Genet. 2010) 46 64

Products for SNORA74B Gene

Sources for SNORA74B Gene

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