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Aliases for SNORA74A Gene

Subcategory (RNA class) for SNORA74A Gene


Quality Score for this RNA gene is


Aliases for SNORA74A Gene

  • Small Nucleolar RNA, H/ACA Box 74A 2 3 5
  • RNA, U19 Small Nucleolar 2 3
  • RNU19 3
  • U19 3

External Ids for SNORA74A Gene

Previous HGNC Symbols for SNORA74A Gene

  • RNU19

Previous GeneCards Identifiers for SNORA74A Gene

  • GC05P138644
  • GC05P138645
  • GC05P138614
  • GC05P133803

Summaries for SNORA74A Gene

GeneCards Summary for SNORA74A Gene

SNORA74A (Small Nucleolar RNA, H/ACA Box 74A) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA74A Gene

Genomics for SNORA74A Gene

Regulatory Elements for SNORA74A Gene

Enhancers for SNORA74A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G139310 1.3 Ensembl ENCODE dbSUPER 11.7 +32.1 32131 0.8 KLF1 ZNF2 RAD21 ZFHX2 ZNF366 SMC3 FOS ZNF600 PRDM10 EGR2 MATR3 PAIP2 SNORA74A SLC23A1 HSPA9 ENSG00000222937 SNORD63 PIR61462 RN7SKP64
GH05G139341 1.2 ENCODE 11.3 +63.5 63535 2.6 MLX CREB3L1 AGO1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SP3 ZNF610 KDM3B PURA RPL7P19 SLC23A1 MZB1 PROB1 MATR3 SNORA74A SIL1 ENSG00000222937
GH05G139304 0.9 dbSUPER 12 +26.9 26874 2.4 HDAC1 CBX3 PKNOX1 ZNF2 RAD21 ZNF335 GATA2 ZSCAN5C ZNF143 EGR2 SNORA74A PAIP2 ENSG00000252213 MATR3 SLC23A1 HSPA9 GC05P139308 RNA5SP195
GH05G139301 0.6 dbSUPER 12 +23.1 23126 0.9 ZNF362 PRDM6 SCRT2 ZKSCAN8 KLF9 ZNF524 SLC23A1 SNORA74A PAIP2 MATR3 ENSG00000252213 RNA5SP195 GC05P139308
GH05G139305 0.6 Ensembl dbSUPER 12 +25.4 25421 0.4 ZNF362 SNORA74A PAIP2 ENSG00000252213 MATR3 SLC23A1 RNA5SP195 GC05P139308
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA74A on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA74A Gene

139,278,780 bp from pter
139,278,979 bp from pter
200 bases
Plus strand

Genomic View for SNORA74A Gene

Genes around SNORA74A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA74A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA74A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA74A Gene

Proteins for SNORA74A Gene

Post-translational modifications for SNORA74A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA74A Gene

Domains & Families for SNORA74A Gene

Gene Families for SNORA74A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA74A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA74A Gene

Function for SNORA74A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA74A Gene

Localization for SNORA74A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA74A Gene

Pathways & Interactions for SNORA74A Gene

SuperPathways for SNORA74A Gene

No Data Available

Interacting Proteins for SNORA74A Gene

Gene Ontology (GO) - Biological Process for SNORA74A Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA74A Gene

Drugs & Compounds for SNORA74A Gene

No Compound Related Data Available

Transcripts for SNORA74A Gene

mRNA/cDNA for SNORA74A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA74A Gene

No ASD Table

Relevant External Links for SNORA74A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA74A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA74A Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA74A Gene:


SOURCE GeneReport for Unigene cluster for SNORA74A Gene:

genes like me logo Genes that share expression patterns with SNORA74A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA74A Gene

Orthologs for SNORA74A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA74A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA74 35
  • 99 (a)
(Bos Taurus)
Mammalia SNORA74 35
  • 89 (a)
(Canis familiaris)
Mammalia SNORA74 35
  • 89 (a)
(Mus musculus)
Mammalia Snora74a 35
  • 87 (a)
(Monodelphis domestica)
Mammalia SNORA74 35
  • 72 (a)
(Danio rerio)
Actinopterygii SNORA74 35
  • 53 (a)
Species where no ortholog for SNORA74A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA74A Gene

Gene Tree for SNORA74A (if available)
Gene Tree for SNORA74A (if available)

Paralogs for SNORA74A Gene

No data available for Paralogs for SNORA74A Gene

Variants for SNORA74A Gene

Sequence variations from dbSNP and Humsavar for SNORA74A Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs141402332 Benign 139,279,060(+) CTTCA(C/T)CTGAA nc-transcript-variant, downstream-variant-500B, utr-variant-5-prime
rs1000173209 -- 139,277,948(+) ATACA(A/G)GCCAG intron-variant, upstream-variant-2KB
rs1004235598 -- 139,278,839(+) TGTTG(A/G)AAGAG intron-variant, nc-transcript-variant
rs1005752066 -- 139,279,225(+) GTAGA(C/G)TATCA intron-variant, nc-transcript-variant, downstream-variant-500B
rs1005854274 -- 139,276,858(+) ACATT(G/T)ATGGT intron-variant, upstream-variant-2KB

Relevant External Links for SNORA74A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA74A Gene

Disorders for SNORA74A Gene

Relevant External Links for SNORA74A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SNORA74A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA74A Gene

Publications for SNORA74A Gene

  1. Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. (PMID: 19240791) Graubert T.A. … Walter M.J. (PLoS ONE 2009) 3 46 64
  2. Human U19 intron-encoded snoRNA is processed from a long primary transcript that possesses little potential for protein coding. (PMID: 9630250) Bortolin M.L. … Kiss T. (RNA 1998) 2 3 64
  3. Characterization of the intron-encoded U19 RNA, a new mammalian small nucleolar RNA that is not associated with fibrillarin. (PMID: 8657112) Kiss T. … Filipowicz W. (Mol. Cell. Biol. 1996) 2 3 64
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORA74A Gene

Sources for SNORA74A Gene

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