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Aliases for SNORA73A Gene

Subcategory (RNA class) for SNORA73A Gene

snoRNA

Quality Score for this RNA gene is

7

Aliases for SNORA73A Gene

  • Small Nucleolar RNA, H/ACA Box 73A 2 3 5
  • RNA, U17a Small Nucleolar 2 3
  • RNA, Small Nucleolar E1 3
  • RNU17A 3
  • E1-7 3
  • U17A 3
  • RNE1 3
  • E1B 3
  • E1 3

External Ids for SNORA73A Gene

ORGUL Members for SNORA73A Gene

Previous HGNC Symbols for SNORA73A Gene

  • RNE1
  • RNU17A

Previous GeneCards Identifiers for SNORA73A Gene

  • GC01P028706
  • GC01P028840
  • GC01P028842
  • GC01P027088
  • GC01P028846
  • GC01P028850
  • GC01P028851
  • GC01P028852
  • GC01P028853
  • GC01P028855
  • GC01P028864

Summaries for SNORA73A Gene

GeneCards Summary for SNORA73A Gene

SNORA73A (Small Nucleolar RNA, H/ACA Box 73A) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORA73A include Maple Syrup Urine Disease, Type Ii.

fRNAdb sequence ontologies for SNORA73A Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA73 family: U17 (SNORA73A and SNORA73B) also known as E1 belongs to the H/ACA class of small nucleolar RNAs (snoRNAs). Vertebrate U17 is intron-encoded and ranges in length from 200-230 nucleotides, longer than most snoRNAs. It is one of the most abundant snoRNAs in human cells and is essential for the cleavage of pre-rRNA within the 5' external transcribed spacer (ETS) [1]. This cleavage leads to the formation of 18S rRNA. Regions of the U17 RNA are complementary to rRNA and act as guides for RNA/RNA interactions, although these regions do not seem to be well conserved between organisms [2].

View fRNAdb secondary structures for SNORA73A

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA73A Gene

Genomics for SNORA73A Gene

Regulatory Elements for SNORA73A Gene

Enhancers for SNORA73A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SNORA73A on UCSC Golden Path with GeneCards custom track

Promoters for SNORA73A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SNORA73A on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA73A Gene

Chromosome:
1
Start:
28,507,365 bp from pter
End:
28,507,571 bp from pter
Size:
207 bases
Orientation:
Plus strand

Genomic View for SNORA73A Gene

Genes around SNORA73A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA73A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA73A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA73A Gene

ORGUL Member Location for SNORA73A Gene

ORGUL Member Location for SNORA73A gene

Proteins for SNORA73A Gene

Post-translational modifications for SNORA73A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA73A Gene

Domains & Families for SNORA73A Gene

Gene Families for SNORA73A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA73A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA73A Gene

Function for SNORA73A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA73A Gene

Localization for SNORA73A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SNORA73A Gene COMPARTMENTS Subcellular localization image for SNORA73A gene
Compartment Confidence
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SNORA73A Gene

Pathways & Interactions for SNORA73A Gene

SuperPathways for SNORA73A Gene

No Data Available

Interacting Proteins for SNORA73A Gene

Gene Ontology (GO) - Biological Process for SNORA73A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA73A Gene

Drugs & Compounds for SNORA73A Gene

No Compound Related Data Available

Transcripts for SNORA73A Gene

fRNAdb Secondary structures for SNORA73A Gene

  • FR020095

mRNA/cDNA for SNORA73A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA73A Gene

No ASD Table

Relevant External Links for SNORA73A Gene

GeneLoc Exon Structure for
SNORA73A
ECgene alternative splicing isoforms for
SNORA73A

Expression for SNORA73A Gene

mRNA expression in normal human tissues for SNORA73A Gene

genes like me logo Genes that share expression patterns with SNORA73A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SNORA73A Gene

Orthologs for SNORA73A Gene

Evolution for SNORA73A Gene

ENSEMBL:
Gene Tree for SNORA73A (if available)
TreeFam:
Gene Tree for SNORA73A (if available)

No data available for Orthologs for SNORA73A Gene

Paralogs for SNORA73A Gene

No data available for Paralogs for SNORA73A Gene

Variants for SNORA73A Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for SNORA73A Gene

Disorders for SNORA73A Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORA73A Gene - From: OMIM

Disorder Aliases PubMed IDs
maple syrup urine disease, type ii
  • dihydrolipoamide dehydrogenase deficiency
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SNORA73A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA73A
genes like me logo Genes that share disorders with SNORA73A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORA73A Gene

Publications for SNORA73A Gene

  1. Small nucleolar RNAs encoded by introns of the human cell cycle regulatory gene RCC1. (PMID: 8335005) Kiss T. … Filipowicz W. (EMBO J. 1993) 1 2 3 67
  2. Three small nucleolar RNAs of unique nucleotide sequences. (PMID: 8421699) Ruff E.A. … Eliceiri G.L. (Proc. Natl. Acad. Sci. U.S.A. 1993) 1 2 3
  3. Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA. (PMID: 8391637) Rimoldi O.J. … Eliceiri G.L. (Mol. Cell. Biol. 1993) 1 3
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  5. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1

Products for SNORA73A Gene

Sources for SNORA73A Gene

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