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Aliases for SNORA71E Gene

Subcategory (RNA class) for SNORA71E Gene

snoRNA

Quality Score for this RNA gene is

12

Aliases for SNORA71E Gene

  • Small Nucleolar RNA, H/ACA Box 71E 2 3 5
  • Small Nucleolar RNA, H/ACA Box 39 2 3
  • ACA39 SnoRNA 3
  • SNORA39 3
  • ACA39 3

External Ids for SNORA71E Gene

Previous HGNC Symbols for SNORA71E Gene

  • SNORA39

Summaries for SNORA71E Gene

GeneCards Summary for SNORA71E Gene

SNORA71E (Small Nucleolar RNA, H/ACA Box 71E) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA71E Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA71: The members of this family belong to the H/ACA class of snoRNAs which bind a number of proteins (including dyskerin, Gar1p and Nop10p) to form snoRNP complexes. This class of snoRNAs are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs [2]. This family includes U71 (SNORA71), ACA39 (SNORA39) and ACA60 (SNORA60) [1,3]. U71 and ACA60 are predicted to guide the pseudouridylation of U406 and U1004 in 18S rRNA respectively [4]. There is currently no target RNA identified for ACA39 [3].

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA71E Gene

Genomics for SNORA71E Gene

Regulatory Elements for SNORA71E Gene


Promoters for SNORA71E Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001837288 -183 201 PKNOX1 MXD3 NBN MLLT1 ELF1 MNT HBP1
ENSR00001448761 -1283 1201 PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF207

Genomic Location for SNORA71E Gene

Chromosome:
20
Start:
38,448,083 bp from pter
End:
38,448,218 bp from pter
Size:
136 bases
Orientation:
Plus strand

Genomic View for SNORA71E Gene

Genes around SNORA71E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA71E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA71E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA71E Gene

ORGUL Member Location for SNORA71E Gene

ORGUL Member Location for SNORA71E gene

Proteins for SNORA71E Gene

Post-translational modifications for SNORA71E Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA71E Gene

Domains & Families for SNORA71E Gene

Gene Families for SNORA71E Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA71E: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA71E Gene

Function for SNORA71E Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA71E Gene

Localization for SNORA71E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA71E Gene

Pathways & Interactions for SNORA71E Gene

SuperPathways for SNORA71E Gene

No Data Available

Interacting Proteins for SNORA71E Gene

Gene Ontology (GO) - Biological Process for SNORA71E Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA71E Gene

Transcripts for SNORA71E Gene

mRNA/cDNA for SNORA71E Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA71E Gene

No ASD Table

Relevant External Links for SNORA71E Gene

GeneLoc Exon Structure for
SNORA71E
ECgene alternative splicing isoforms for
SNORA71E

Expression for SNORA71E Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA71E Gene:

SNORA71E
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORA71E Gene

Orthologs for SNORA71E Gene

Evolution for SNORA71E Gene

ENSEMBL:
Gene Tree for SNORA71E (if available)
TreeFam:
Gene Tree for SNORA71E (if available)

No data available for Orthologs for SNORA71E Gene

Paralogs for SNORA71E Gene

No data available for Paralogs for SNORA71E Gene

Variants for SNORA71E Gene

Sequence variations from dbSNP and Humsavar for SNORA71E Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs111823403 -- 38,448,489(+) CATCC(A/G)CTGTC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112136513 -- 38,447,923(+) AAGCC(-/T)TTTTT intron-variant, upstream-variant-2KB
rs114424612 -- 38,446,283(+) GGCTG(C/T)CATAA upstream-variant-2KB
rs114513976 -- 38,448,058(+) CTGTT(C/G)CTGGA intron-variant, upstream-variant-2KB
rs115778913 -- 38,447,423(+) TGCCA(A/G)GACCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA71E Gene

Variant ID Type Subtype PubMed ID
esv2758794 CNV gain 17122850
esv35121 CNV gain 17911159
nsv1058457 CNV loss 25217958
nsv1063495 CNV gain 25217958
nsv509769 CNV insertion 20534489
nsv817893 CNV gain 17921354

Relevant External Links for SNORA71E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA71E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA71E Gene

Disorders for SNORA71E Gene

Relevant External Links for SNORA71E

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA71E

No disorders were found for SNORA71E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA71E Gene

Publications for SNORA71E Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1 2 3 64
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 1 2 3 64
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  4. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) . … Gojobori T. (Nucleic Acids Res. 2008) 1
  5. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C. … Chen R. (Nucleic Acids Res. 2005) 1

Products for SNORA71E Gene

Sources for SNORA71E Gene

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