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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNORA71B Gene

RNA gene   GIFtS: 20
GCID: GC20M037066

small nucleolar RNA, H/ACA box 71B

(Previous names: RNA, U71B small nucleolar )
(Previous symbol: RNU71B)
  Search for SNORA71B
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Biological research products
for SNORA71B    

Aliases
for SNORA71B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Subcategory (RNA class): snoRNA

Quality score for this RNA gene is 6

Aliases
Small Nucleolar RNA, H/ACA Box 71B1 2
RNU71B1 2
U71b1 2
RNA, U71B Small Nucleolar1

External Ids:    HGNC: 102331   Entrez Gene: 267762   Ensembl: ENSG000002014167   
ORGUL members:    fRNAdb10:FR351835 FR305034 FR351835 FR327755 FR305034      
H-InvDB:HIT000383122    
NCBI:Y11166 Y11166 BX640887 AL080249 Y11166    
NONCODE:u5127    
Rfam:RF00056    
RNAdb:SNO1569    

Export aliases for SNORA71B gene to outside databases

Previous GC identifers: GC20M036494 GC20M036500 GC20M037054 GC20M033788


Summaries
for SNORA71B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
fRNAdb sequence ontology for SNORA71B:
H_ACA_box_snoRNA - Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

View fRNAdb secondary structures for SNORA71B

Genomic Views
for SNORA71B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNORA71B gene promoter:
         GR   Elk-1   GR-beta   COMP1   GR-alpha   POU3F2   GATA-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNORA71B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.23   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.23

SNORA71B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNORA71B gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M037066:  view genomic region     (about GC identifiers)

Start:
 37,053,843 bp from pter      End:
 37,053,979 bp from pter
Size:
 137 bases      Orientation:
 minus strand
ORGUL member locations:
Legend (see complete legend)

  • FR0351835
  • FR0327755
  • FR0377587
  • FR0305034
37053842 37053911 37053980 chr20

Proteins
for SNORA71B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB: --

Protein Domains /
Families
for SNORA71B gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
   --

Function
for SNORA71B gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
miRNA
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Inhib. RNA
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In Situ Assay
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Pathways & Interactions
for SNORA71B gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNORA71B

Drugs & Compounds
for SNORA71B gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SNORA71B
Search CenterWatch for drugs/clinical trials and news about SNORA71B 

Transcripts
for SNORA71B gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
 4 fRNAdb Secondary structures:


Unigene Cluster for SNORA71B:

Small nucleolar RNA, H/ACA box 71B
Hs.743872
Unigene Representative Sequence: Y11166
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000364546(snoRNA)

miRNA
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Inhib. RNA
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Additional cDNA sequence: 

NR_002910.2 Y11166.1 

GeneLoc Exon Structure


Expression
for SNORA71B gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for SNORA71B:H-invDB

SNORA71B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image
Genevestigator expression for SNORA71B

SOURCE GeneReport for Unigene cluster: Hs.743872
    SABiosciences Custom PCR Arrays for SNORA71B
Primer
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In Situ
Assay Products: 
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Orthologs
for SNORA71B gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
   --

ENSEMBL Gene Tree for SNORA71B (if available)
TreeFam Gene Tree for SNORA71B (if available) 

Paralogs
for SNORA71B gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for SNORA71B gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/43 NCBI SNPs in SNORA71B are shown (see all 43)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 20 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1159034991,2
F,--37053423(+) TGTGGC/GTCCAA 3 -- int1 ds50011Minor allele frequency- G:0.03WA 118
rs1162525131,2
F,--37053570(+) CAATAG/CCTTCT 3 -- int1 ds50011Minor allele frequency- C:0.03WA 118
rs17806361,2
C,F,A,H,--37053583(+) GGAAAT/CGAGGG 3 -- int1 ds500124Minor allele frequency- C:0.25NS EA NA WA CSA 2230
rs1907091891,2
--37053608(+) TTACTA/GGGGGA 3 -- int1 ds50010--------
rs20383291,2
H--37053641(+) attttA/Tcaagt 3 -- ds5001 int14Minor allele frequency- T:0.00NS EA 418
rs1414306001,2
--37053664(+) CCCATC/TCAGCC 3 -- ds5001 int10--------
rs1137983011,2
C,--37053708(+) CCCCAG/TATAAA 3 -- int1 ds50011Minor allele frequency- T:0.50NA 2
rs794355131,2
F,--37053908(+) GCGCTT/GTCATT 3 -- int1 nc-transcript-variant1Minor allele frequency- G:0.03WA 118
rs1820293571,2
--37054105(+) TGCTTC/GTGATT 3 -- int1 us2k10--------
rs759842161,2
C--37054107(+) CTTCTC/GATTCC 3 -- int1 us2k10--------

HapMap Linkage Disequilibrium report for SNORA71B (37053843 - 37053979 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SNORA71B
     4 CNVs: 9824 8884 3217 4101

SABiosciences Cancer Mutation PCR Assays
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Disorders / Diseases
for SNORA71B gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
SNORA71B for disorders           About MalaCards

SNORA71B for disorders           About GeneDecksing

OMIM gene information: 217400 605804 607116 608031 608559 610245    

Export disorders for SNORA71B gene to outside databases

Publications
for SNORA71B gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for SNORA71B gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SNORA71B)		    Utopia: connect your pdf to the dynamic
world of online information

  1. The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. (PubMed id 9106664)1, 3 Ganot P....Kiss T. (1997)
  2. Eukaryotic snoRNAs: a paradigm for gene expression fl exibility. (PubMed id 19446021)1 Dieci G....Montanini B. (2009)
  3. Human box H/ACA pseudouridylation guide RNA machinery. (PubMed id 15199136)1 Kiss A.M....Kiss T. (2004)
  4. (PubMed id 9182768)10 
  5. (PubMed id 16381836)10 
  6. (PubMed id 15608161)10 
  7. (PubMed id 8797828)10 
  8. (PubMed id 10736225)10 
  9. (PubMed id 15103394)10 
  10. (PubMed id 18089548)10 

External Searches for SNORA71B gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing SNORA71B gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 26776 HGNC: 10233 Ensembl:ENSG00000201416 euGenes: HUgn26776 ECgene: SNORA71B
H-InvDB: SNORA71B

Other Databases showing SNORA71B gene

(According to HUGE)
About This Section
   --

Specialized Databases showing SNORA71B gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for SNORA71B Pharmacogenomics, SNPs, Pathways

Intellectual Property
for SNORA71B gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for SNORA71B gene:
Search GeneIP for patents involving SNORA71B

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for SNORA71B gene

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