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Aliases for SNORA70D Gene

Subcategory (RNA class) for SNORA70D Gene


Quality Score for this RNA gene is


Aliases for SNORA70D Gene

  • Small Nucleolar RNA, H/ACA Box 70D 2 3 5
  • Small Nucleolar RNA, H/ACA Box 70D (Retrotransposed) 2 3
  • U70D 3

External Ids for SNORA70D Gene

ORGUL Members for SNORA70D Gene

Previous GeneCards Identifiers for SNORA70D Gene

  • GC00U922445
  • GC16U901183
  • GC16M071733
  • GC16M057500
  • GC16M071736

Summaries for SNORA70D Gene

GeneCards Summary for SNORA70D Gene

SNORA70D (Small Nucleolar RNA, H/ACA Box 70D) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA70D Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA70: snoRNA U70 seems to be exclusive to mammals and is a member of the H/ACA class of snoRNA which contain H (ANANNA) and ACA box motifs. H/ACA box snoRNAs are involved in the conversion of uridines to pseudouridines (5-ribosyluracil) a constituent of structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar) [1,2].

View fRNAdb secondary structures for SNORA70D

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA70D Gene

Genomics for SNORA70D Gene

Regulatory Elements for SNORA70D Gene

Enhancers for SNORA70D Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F071669 0.6 ENCODE 11 +28.2 28178 2.0 ELF3 CTCF SOX13 TBP TFAP4 MXI1 ATF1 SAP130 ARID4B ZNF384 PHLPP2 SNORA70D TAT HPR RNU6-208P
GH16F071625 0.7 Ensembl ENCODE 10.6 +71.2 71246 3.7 ZFP64 ARID4B SIN3A DMAP1 RAD21 ZNF2 SLC30A9 ZNF121 SCRT2 ZNF391 PHLPP2 RNU6-208P TAT SNORA70D MARVELD3 HPR ENSG00000260593 LOC105371336
GH16F071630 0.4 ENCODE 10.6 +67.7 67719 0.1 DPF2 ZNF217 CTBP1 JUND GATA3 FOS CUX1 RCOR1 RNU6-208P PHLPP2 TAT SNORA70D ENSG00000260593 LOC105371336
GH16F071629 0.2 ENCODE 10.6 +68.9 68869 0.2 ZBTB40 TAT-AS1 RNU6-208P PHLPP2 TAT SNORA70D ENSG00000260593 LOC105371336
GH16F071636 0.8 ENCODE 10.2 +61.1 61063 1.4 TBP ELF3 ARID4B RAD21 SCRT2 CREM EGR2 HCFC1 KAT8 NFIL3 RNU6-208P PHLPP2 SNORA70D CALB2 LOC105371336 PIR51866
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SNORA70D on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA70D Gene

71,698,567 bp from pter
71,698,701 bp from pter
135 bases
Minus strand

Genomic View for SNORA70D Gene

Genes around SNORA70D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA70D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA70D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA70D Gene

ORGUL Member Location for SNORA70D Gene

ORGUL Member Location for SNORA70D gene

Proteins for SNORA70D Gene

Post-translational modifications for SNORA70D Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA70D Gene

Domains & Families for SNORA70D Gene

Gene Families for SNORA70D Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA70D: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA70D Gene

Function for SNORA70D Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA70D Gene

Localization for SNORA70D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA70D Gene

Pathways & Interactions for SNORA70D Gene

SuperPathways for SNORA70D Gene

No Data Available

Interacting Proteins for SNORA70D Gene

Gene Ontology (GO) - Biological Process for SNORA70D Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA70D Gene

Transcripts for SNORA70D Gene

fRNAdb Secondary structures for SNORA70D Gene

  • RF00156;SNORA70;DAAB013739299.1/461-547

mRNA/cDNA for SNORA70D Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA70D Gene

No ASD Table

Relevant External Links for SNORA70D Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA70D Gene

mRNA expression in normal human tissues for SNORA70D Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA70D Gene:


SOURCE GeneReport for Unigene cluster for SNORA70D Gene:

genes like me logo Genes that share expression patterns with SNORA70D: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORA70D Gene

Orthologs for SNORA70D Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA70D Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA70 35
  • 96 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA70 35
  • 71 (a)
(Canis familiaris)
Mammalia SNORA70 35
  • 68 (a)
(Mus musculus)
Mammalia Gm22163 35
  • 62 (a)
(Danio rerio)
Actinopterygii SNORA70 35
  • 57 (a)
Species where no ortholog for SNORA70D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA70D Gene

Gene Tree for SNORA70D (if available)
Gene Tree for SNORA70D (if available)

Paralogs for SNORA70D Gene

No data available for Paralogs for SNORA70D Gene

Variants for SNORA70D Gene

Sequence variations from dbSNP and Humsavar for SNORA70D Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs112185530 -- 71,698,261(+) ACCCC(A/G)CAGCC intron-variant, downstream-variant-500B
rs113179515 -- 71,698,168(+) TTGGT(G/T)AGCAT intron-variant, downstream-variant-500B
rs114919842 -- 71,700,279(+) GCGCA(C/T)GTGTA intron-variant, upstream-variant-2KB
rs116853562 -- 71,700,305(+) GAGGC(C/T)GAGGT intron-variant, upstream-variant-2KB
rs116951371 -- 71,699,939(+) CCCAG(A/T)GAACA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA70D Gene

Variant ID Type Subtype PubMed ID
nsv1063338 CNV gain 25217958
nsv7285 OTHER inversion 18451855
nsv984350 CNV duplication 23825009

Relevant External Links for SNORA70D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA70D Gene

Disorders for SNORA70D Gene

Relevant External Links for SNORA70D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SNORA70D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA70D Gene

Publications for SNORA70D Gene

  1. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  2. Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. (PMID: 12007400) Kiss T. (Cell 2002) 1
  3. Pseudouridine in RNA: what, where, how, and why. (PMID: 10902565) Charette M. … Gray M.W. (IUBMB Life 2000) 1

Products for SNORA70D Gene

Sources for SNORA70D Gene

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