SNORA70C Gene
RNA gene GIFtS: 18
GCID: GC09M119944
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small nucleolar RNA, H/ACA box 70C(Previous names: small nucleolar RNA, H/ACA box 70C (retrotransposed) )
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Aliases
for SNORA70C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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Subcategory (RNA class): snoRNA
Quality score for this RNA gene is 4
| Aliases |
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| Small Nucleolar RNA, H/ACA Box 70C1 2 | | Small Nucleolar RNA, H/ACA Box 70C (Retrotransposed)1 | | U70C2 |
| External Ids: | HGNC: 336191 | Entrez Gene: 1001245382 | Ensembl: ENSG000002072687 |
Export aliases for SNORA70C gene to outside databasesPrevious GC identifers: GC09U900874 GC09M118985 GC09M089562
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Summaries
for SNORA70C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SNORA70C:
This gene produces a small nucleolar RNA (snoRNA) that plays a role in post-transcriptional modification. This snoRNAis a type-3 retrotransposed snoRNA, where the ribosomal protein L10 gene on chromosome X is its parental gene, andthis, together with part of the parental gene, was subsequently mobilized into an intron of the astrotactin 2 hostgene on chromosome 9. This snoRNA contains a H/ACA box, which serves as a guide for the pseudouridylation of selectedbases of ribosomal RNA by forming short duplexes with the 18S rRNA U1692, the target for this snoRNA. This gene isspecific to human, chimp and orangutan, and is not found in the genomes of rhesus or marmoset. (provided by RefSeq,Jun 2010)
fRNAdb sequence ontology for SNORA70C:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
View fRNAdb secondary structures for SNORA70C |
Genomic Views
for SNORA70C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SNORA70C gene promoter:
E2F-4 E2F-3a STAT1 E2F-5 E2F-1 E2F STAT2 STAT1beta E2F-2 STAT1alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for SNORA70C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNORA70C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q33.1 Ensembl cytogenetic band: 9q33.1 HGNC cytogenetic band: 9q33.1SNORA70C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M119944: view genomic region
(about GC identifiers)
Start:
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119,943,345 bp from pter |
End:
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119,943,480 bp from pter |
Size:
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136 bases |
Orientation:
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minus strand |
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Proteins
for SNORA70C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for SNORA70C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for SNORA70C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Pathways & Interactions
for SNORA70C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNORA70C
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Drugs & Compounds
for SNORA70C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SNORA70C
Search CenterWatch for drugs/clinical trials and news about SNORA70C 
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Transcripts
for SNORA70C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
| 1 fRNAdb Secondary structure:
Unigene Cluster for SNORA70C: Small nucleolar RNA, H/ACA box 70C Hs.693445 Unigene Representative Sequence: NR_0037081 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000384538(snoRNA)
Additional cDNA sequence: NR_003708.4
GeneLoc Exon Structure
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Expression
for SNORA70C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for SNORA70C:H-invDB
SNORA70C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
SOURCE GeneReport for Unigene cluster: Hs.693445
SABiosciences Custom PCR Arrays for SNORA70C
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SNORA70C | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNORA70C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNORA70C |
Orthologs
for SNORA70C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for SNORA70C (if available)
TreeFam Gene Tree for SNORA70C (if available) |
Paralogs
for SNORA70C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for SNORA70C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SNORA70C
1 CNV: 7721 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for SNORA70C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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 SNORA70C for disorders About MalaCards
SNORA70C for disorders About GeneDecksing
OMIM gene information: 612856
Export disorders for SNORA70C gene to outside databases
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Publications
for SNORA70C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for SNORA70C gene integrated from 9 sources:
(articles sorted by number of sources associating them with SNORA70C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Eukaryotic snoRNAs: a paradigm for gene expression fl exibility. (PubMed id 19446021)1 Dieci G....Montanini B. (2009)
- Genome-wide analyses of retrogenes derived from the h uman box H/ACA snoRNAs. (PubMed id 17175533)1 Luo Y. and Li S. (2007)
- snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PubMed id 16990247)1 Yang J.H....Qu L.H. (2006)
- Mammalian small nucleolar RNAs are mobile genetic elements. (PubMed id 17154719)1 Weber M.J. (2006)
- (PubMed id 15103394)10
- (PubMed id 18089548)10
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External Searches for SNORA70C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SNORA70C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing SNORA70C gene
(According to HUGE)
About This Section
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Specialized Databases showing SNORA70C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for SNORA70C | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for SNORA70C gene:
Search GeneIP for patents involving SNORA70C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SNORA70C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNORA70C | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNORA70C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNORA70C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNORA70C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNORA70C | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNORA70C |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for SNORA70C |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNORA70C |
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Last full update: 19 Mar 2013 -
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