Aliases for SNORA70B Gene
Subcategory (RNA class) for SNORA70B Gene
Quality Score for this RNA gene is
Aliases for SNORA70B Gene
External Ids for SNORA70B Gene
- HGNC: 33618
- Entrez Gene: 100124537
- Ensembl: ENSG00000206937
Previous GeneCards Identifiers for SNORA70B Gene
- GC02U901156
- GC02M061501
- GC02M061645
Summaries for SNORA70B Gene
GeneCards Summary for SNORA70B Gene
SNORA70B (Small Nucleolar RNA, H/ACA Box 70B) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORA70B Gene - the ORGUL cluster for this gene includes several descriptions:
-
H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.
-
Small nucleolar RNA SNORA70: snoRNA U70 seems to be exclusive to mammals and is a member of the H/ACA class of snoRNA which contain H (ANANNA) and ACA box motifs. H/ACA box snoRNAs are involved in the conversion of uridines to pseudouridines (5-ribosyluracil) a constituent of structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar) [1,2].
Additional gene information for SNORA70B Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA70B Gene
Genomics for SNORA70B Gene
GeneHancer (GH) Regulatory Elements for SNORA70B Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH02I061417 | Enhancer | 0.3 | FANTOM5 | 550.8 | -0.3 | -310 | 0.1 | ZNF316 | ENSG00000234624 SNORA70B AHSA2P USP34 | |
GH02I061477 | Enhancer | 0.4 | UCNEbase | 10.3 | -60.7 | -60691 | 0.3 | SNORA70B ENSG00000234624 CCT4 COMMD1 LOC105377633 PIR55828 XPO1 | ||
GH02I061478 | Enhancer | 0.2 | dbSUPER | 10.9 | -61.3 | -61308 | 0.6 | SNORA70B ENSG00000234624 CCT4 COMMD1 AHSA2P LOC105377633 PIR55828 XPO1 | ||
GH02I061468 | Promoter/Enhancer | 2.5 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 0.2 | -53.2 | -53227 | 4.7 | HDGF PKNOX1 FOXA2 SMAD1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 | USP34 LOC105377633 LOC339803 AHSA2P PAPOLG PEX13 PUS10 SNORA70B | |
GH02I061424 | Enhancer | 1.2 | FANTOM5 Ensembl ENCODE | 0.4 | -8.4 | -8445 | 2.3 | CTCF SAP130 ARID4B ZNF384 EBF1 IRF4 ZNF48 RAD21 CHAMP1 GATAD1 | AHSA2P LOC339803 USP34 CCT4 COMMD1 SNORA70B |
Regulatory Element Products
Genomic Locations for SNORA70B Gene
- chr2:61,417,244-61,417,378
- (GRCh38/hg38)
- Size:
- 135 bases
- Orientation:
- Minus strand
- chr2:61,644,379-61,644,513
- (GRCh37/hg19)
Genomic View for SNORA70B Gene
- Cytogenetic band:
-
- 2p15 by Ensembl
- 2p15 by Entrez Gene
- 2p15 by HGNC


RefSeq DNA sequence for SNORA70B Gene
ORGUL Member Location for SNORA70B Gene

Proteins for SNORA70B Gene
Post-translational modifications for SNORA70B Gene
Antibody Products
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Protein Products
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No data available for DME Specific Peptides for SNORA70B Gene
Domains & Families for SNORA70B Gene
Gene Families for SNORA70B Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA70B Gene
Function for SNORA70B Gene
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-
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-
Vectors and viruses for KO, Activation, Repression, and more
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SNORA70B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA70B Gene
Localization for SNORA70B Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA70B Gene
Transcripts for SNORA70B Gene
mRNA/cDNA for SNORA70B Gene
- (1) Additional mRNA sequences :
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SNORA70B Gene
CRISPR Products
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- Applied Biological Materials CRISPR for SNORA70B
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for SNORA70B
Inhibitory RNA Products
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Clone Products
- GenScript: Custom all cDNA clones Services for SNORA70B
- VectorBuilder custom plasmid, inducible vectors for SNORA70B
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SNORA70B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for SNORA70B Gene
NURSA nuclear receptor signaling pathways regulating expression of SNORA70B Gene:
SNORA70BSOURCE GeneReport for Unigene cluster for SNORA70B Gene:
Hs.675825Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA70B Gene
Orthologs for SNORA70B Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | SNORA70 34 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | SNORA70 34 |
|
ManyToMany | |
platypus (Ornithorhynchus anatinus) |
Mammalia | SNORA70 34 |
|
ManyToMany | |
mouse (Mus musculus) |
Mammalia | Gm23902 34 |
|
ManyToMany | |
zebrafish (Danio rerio) |
Actinopterygii | SNORA70 34 |
|
ManyToMany |
- Species where no ortholog for SNORA70B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for SNORA70B Gene
No data available for Paralogs for SNORA70B Gene
Variants for SNORA70B Gene
SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000184757 | -- | 61,416,846(-) | G/A | downstream_transcript_variant | |
rs1001230128 | -- | 61,419,172(-) | T/C | upstream_transcript_variant | |
rs1001777853 | -- | 61,419,367(-) | G/T | upstream_transcript_variant | |
rs1002078971 | -- | 61,418,733(-) | C/A | upstream_transcript_variant | |
rs1002128166 | -- | 61,419,134(-) | G/A | upstream_transcript_variant |
Additional Variant Information for SNORA70B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SNORA70B
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA70B Gene
Disorders for SNORA70B Gene
Additional Disease Information for SNORA70B
No disorders were found for SNORA70B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA70B Gene
Publications for SNORA70B Gene
- Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
- snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PMID: 16990247) Yang JH … Qu LH (Nucleic acids research 2006) 3 58
- Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. (PMID: 12007400) Kiss T (Cell 2002) 1
- Pseudouridine in RNA: what, where, how, and why. (PMID: 10902565) Charette M … Gray MW (IUBMB life 2000) 1
Products for SNORA70B Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for SNORA70B
- VectorBuilder custom plasmid, inducible vectors for SNORA70B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SNORA70B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for SNORA70B
- Search GeneTex for Proteins for SNORA70B
Sources for SNORA70B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
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- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
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- (125) NCBI Bookshelf
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- (128) ViGene Biosciences
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- (133) ENCODE
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- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew