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SNORA70B Gene(RNA Gene)

Small Nucleolar RNA, H/ACA Box 70B

GCID:
GC02M061384
GIFtS:
17
Genes Participants
UDN Logo

Aliases for SNORA70B Gene

Subcategory (RNA class) for SNORA70B Gene

snoRNA

Quality Score for this RNA gene is

5

Aliases for SNORA70B Gene

  • Small Nucleolar RNA, H/ACA Box 70B 2 3 5
  • Small Nucleolar RNA, H/ACA Box 70B (Retrotransposed) 2

External Ids for SNORA70B Gene

ORGUL Members for SNORA70B Gene

Previous GeneCards Identifiers for SNORA70B Gene

  • GC02U901156
  • GC02M061501
  • GC02M061645

Summaries for SNORA70B Gene

GeneCards Summary for SNORA70B Gene

SNORA70B (Small Nucleolar RNA, H/ACA Box 70B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA70B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA70: snoRNA U70 seems to be exclusive to mammals and is a member of the H/ACA class of snoRNA which contain H (ANANNA) and ACA box motifs. H/ACA box snoRNAs are involved in the conversion of uridines to pseudouridines (5-ribosyluracil) a constituent of structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar) [1,2].

View fRNAdb secondary structures for SNORA70B

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA70B Gene

Genomics for SNORA70B Gene

Products:

  1. Regulatory Element

Regulatory Elements for SNORA70B Gene

Enhancers for SNORA70B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SNORA70B on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the SNORA70B gene promoter:

Genomic Location for SNORA70B Gene

Chromosome:
2
Start:
61,417,244 bp from pter
End:
61,417,378 bp from pter
Size:
135 bases
Orientation:
Minus strand

Genomic View for SNORA70B Gene

Genes around SNORA70B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA70B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA70B Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORA70B Gene

ORGUL Member Location for SNORA70B Gene

ORGUL Member Location for SNORA70B gene

Proteins for SNORA70B Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for SNORA70B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA70B Gene

Domains & Families for SNORA70B Gene

Gene Families for SNORA70B Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA70B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA70B Gene

Function for SNORA70B Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA70B Gene

Localization for SNORA70B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA70B Gene

Pathways & Interactions for SNORA70B Gene

SuperPathways for SNORA70B Gene

PathCards logoMore details on SuperPathways for SNORA70B
No Data Available

Interacting Proteins for SNORA70B Gene

Gene Ontology (GO) - Biological Process for SNORA70B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA70B Gene

Drugs & Compounds for SNORA70B Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for SNORA70B Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

fRNAdb Secondary structures for SNORA70B Gene

  • RF00156;SNORA70;DAAB010734333.1/305-390

mRNA/cDNA for SNORA70B Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA70B Gene

Small nucleolar RNA, H/ACA box 70B:
Representative Sequences:

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA70B Gene

No ASD Table

Relevant External Links for SNORA70B Gene

GeneLoc Exon Structure for
SNORA70B
ECgene alternative splicing isoforms for
SNORA70B

Expression for SNORA70B Gene

Products:

  1. Primer

mRNA expression in normal human tissues for SNORA70B Gene

mRNA expression in normal human tissues for SNORA70B Gene
mRNA expression by GTEx for SNORA70B Gene

SOURCE GeneReport for Unigene cluster for SNORA70B Gene Hs.675825

genes like me logo Genes that share expression patterns with SNORA70B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SNORA70B Gene

Orthologs for SNORA70B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA70B Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
 Mammalia SNORA70 36
  • 76 (a)
 ManyToMany
mouse
(Mus musculus)
 Mammalia Gm23902 36
  • 66 (a)
 ManyToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia SNORA70 36
  • 71 (a)
 ManyToMany
chimpanzee
(Pan troglodytes)
 Mammalia SNORA70 36
  • 99 (a)
 OneToOne
zebrafish
(Danio rerio)
 Actinopterygii SNORA70 36
  • 65 (a)
 ManyToMany
Species with no ortholog for SNORA70B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA70B Gene

ENSEMBL:
Gene Tree for SNORA70B (if available)
TreeFam:
Gene Tree for SNORA70B (if available)

Paralogs for SNORA70B Gene

No data available for Paralogs for SNORA70B Gene

Variants for SNORA70B Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA70B Gene

Variant ID Type Subtype PubMed ID
nsv874212 CNV Gain 21882294
dgv4158n71 CNV Loss 21882294
nsv7313 OTHER Inversion 18451855

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for SNORA70B Gene

Disorders for SNORA70B Gene

Relevant External Links for SNORA70B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA70B

No disorders were found for SNORA70B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA70B Gene

Publications for SNORA70B Gene

  1. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 67
  2. snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome. (PMID: 16990247) Yang J.H. … Qu L.H. (Nucleic Acids Res. 2006) 3
  3. Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. (PMID: 12007400) Kiss T. (Cell 2002) 1
  4. Pseudouridine in RNA: what, where, how, and why. (PMID: 10902565) Charette M. … Gray M.W. (IUBMB Life 2000) 1

Products for SNORA70B Gene

Sources for SNORA70B Gene

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