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Aliases for SNORA70 Gene

Subcategory (RNA class) for SNORA70 Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORA70 Gene

  • Small Nucleolar RNA, H/ACA Box 70 2 3 5
  • RNA, U70 Small Nucleolar 2 3
  • U70 Small Nucleolar RNA 3
  • U70 SnoRNA 3
  • DXS648E 3
  • RNU70 3
  • U70 3

External Ids for SNORA70 Gene

Previous HGNC Symbols for SNORA70 Gene

  • RNU70

Previous GeneCards Identifiers for SNORA70 Gene

  • GC0XP153281
  • GC0XP153628

Summaries for SNORA70 Gene

GeneCards Summary for SNORA70 Gene

SNORA70 (Small Nucleolar RNA, H/ACA Box 70) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA70 Gene

Genomics for SNORA70 Gene

Regulatory Elements for SNORA70 Gene

Enhancers for SNORA70 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG153900 1.6 FANTOM5 Ensembl ENCODE 31.6 -497.8 -497777 4.2 HDGF AGO1 ZFP64 GLI4 TCF12 ZNF766 GLIS2 GATA2 ZNF143 FOS SNORA70 LOC105373383 HCFC1 TMEM187 PLXNA3 ENSG00000261773 EMD PLXNB3 GDI1 LOC102723591
GH0XG154723 1.9 FANTOM5 Ensembl ENCODE dbSUPER 19.3 +331.1 331144 16.0 HDGF FOXA2 ZFP64 SIN3A ZNF2 YY1 GLIS2 ELK1 ZNF143 KLF7 F8A1 GAB3 F8A2 SNORA70 EMD DKC1 MPP1 IKBKG HCFC1 PLXNA3
GH0XG154796 2 FANTOM5 Ensembl ENCODE dbSUPER 14.2 +401.1 401120 10.1 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 F8A1 SNORA56 F8A2 SNORA70 SNORA36A DKC1 IKBKG TMLHE GAB3 EMD
GH0XG154246 0.9 Ensembl 28.9 -152.6 -152581 2.6 ZNF473 ZSCAN4 GLI4 ZNF335 GLIS2 EGR1 EGR2 ZNF680 YY2 ZIK1 PLXNA3 SNORA70 HCFC1 LOC105373383 ENSG00000261773 EMD GDI1 PDZD4 L1CAM LOC102030688
GH0XG153965 1.8 FANTOM5 ENCODE dbSUPER 14.4 -429.8 -429766 10.0 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 WRNIP1 SIN3A FEZF1 DMAP1 TMEM187 SNORA70 SNORA56 FAM3A ABCD1 PLXNB3 ARHGAP4 MECP2 RENBP DNASE1L1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA70 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the SNORA70 gene promoter:

Genomic Location for SNORA70 Gene

Chromosome:
X
Start:
154,400,281 bp from pter
End:
154,400,415 bp from pter
Size:
135 bases
Orientation:
Plus strand

Genomic View for SNORA70 Gene

Genes around SNORA70 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA70 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA70 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA70 Gene

Proteins for SNORA70 Gene

Post-translational modifications for SNORA70 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA70 Gene

Domains & Families for SNORA70 Gene

Gene Families for SNORA70 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA70: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA70 Gene

Function for SNORA70 Gene

Animal Model Products

miRNA for SNORA70 Gene

miRTarBase miRNAs that target SNORA70

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNORA70 Gene

Localization for SNORA70 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORA70 gene
Compartment Confidence
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SNORA70 Gene

Pathways & Interactions for SNORA70 Gene

SuperPathways for SNORA70 Gene

No Data Available

Interacting Proteins for SNORA70 Gene

Gene Ontology (GO) - Biological Process for SNORA70 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA70 Gene

Drugs & Compounds for SNORA70 Gene

No Compound Related Data Available

Transcripts for SNORA70 Gene

mRNA/cDNA for SNORA70 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA70 Gene

No ASD Table

Relevant External Links for SNORA70 Gene

GeneLoc Exon Structure for
SNORA70
ECgene alternative splicing isoforms for
SNORA70

Expression for SNORA70 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA70 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA70 Gene:

SNORA70
genes like me logo Genes that share expression patterns with SNORA70: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA70 Gene

Orthologs for SNORA70 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA70 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA70 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA70 35
  • 76 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA70 35
  • 74 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm24787 35
  • 71 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA70 35
  • 62 (a)
ManyToMany
Species where no ortholog for SNORA70 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA70 Gene

ENSEMBL:
Gene Tree for SNORA70 (if available)
TreeFam:
Gene Tree for SNORA70 (if available)

Paralogs for SNORA70 Gene

No data available for Paralogs for SNORA70 Gene

Variants for SNORA70 Gene

Sequence variations from dbSNP and Humsavar for SNORA70 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs138325578 Uncertain significance 154,399,903(+) GTCAT(C/T)CGCAT upstream-variant-2KB, reference, synonymous-codon
rs369963498 Uncertain significance 154,400,856(+) ATGAG(A/G)GCTTC downstream-variant-500B, reference, missense, utr-variant-3-prime
rs12012747 other 154,400,814(+) CCCCA(A/G)TCGTG downstream-variant-500B, reference, missense, utr-variant-3-prime
rs2070820 other 154,398,551(+) AGTCT(A/T)GAATC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs387906727 other 154,400,825(-) GTCCA(G/T)AGGGC downstream-variant-500B, reference, synonymous-codon, missense, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SNORA70 Gene

Variant ID Type Subtype PubMed ID
esv33199 CNV gain+loss 17666407
esv33784 CNV gain+loss 17666407
nsv220 OTHER inversion 15895083
nsv519042 CNV gain 19592680
nsv7468 OTHER inversion 18451855

Relevant External Links for SNORA70 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA70

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA70 Gene

Disorders for SNORA70 Gene

Relevant External Links for SNORA70

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA70

No disorders were found for SNORA70 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA70 Gene

Publications for SNORA70 Gene

  1. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3 64
  2. The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. (PMID: 9106664) Ganot P. … Kiss T. (Genes Dev. 1997) 2 3 64
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  4. Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. (PMID: 8733135) Chen E.Y. … D'Urso M. (Hum. Mol. Genet. 1996) 3 64

Products for SNORA70 Gene

Sources for SNORA70 Gene

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