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Aliases for SNORA68 Gene

Subcategory (RNA class) for SNORA68 Gene


Quality Score for this RNA gene is


Aliases for SNORA68 Gene

  • Small Nucleolar RNA, H/ACA Box 68 2 3 5
  • RNA, U68 Small Nucleolar 2 3
  • U68 Small Nucleolar RNA 3
  • U68 SnoRNA 3
  • SNORA68A 3
  • RNU68 3
  • U68 3

External Ids for SNORA68 Gene

Previous HGNC Symbols for SNORA68 Gene

  • RNU68

Previous GeneCards Identifiers for SNORA68 Gene

  • GC19P017837
  • GC19P017973
  • GC19P017538
  • GC19P017971
  • GC19P018176
  • GC19P018294
  • GC19P018328
  • GC19P018701
  • GC19P019011

Summaries for SNORA68 Gene

GeneCards Summary for SNORA68 Gene

SNORA68 (Small Nucleolar RNA, H/ACA Box 68) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA68 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA68: U68 is a member of the H/ACA class of small nucleolar RNAs (snoRNAs) which act as guides in the the modification of uridines to pseudouridines [2].

Additional gene information for SNORA68 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA68 Gene

Genomics for SNORA68 Gene

Regulatory Elements for SNORA68 Gene

Enhancers for SNORA68 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H017775 1.2 Ensembl ENCODE 11.7 -86.2 -86234 1.8 HDAC1 HDGF PKNOX1 TBL1XR1 RB1 YBX1 BATF THRB RAD21 GATA2 FCHO1 UNC13A RPL18A INSL3 SNORA68 GC19M017755 B3GNT3
GH19H017915 0.8 ENCODE 12.6 +53.7 53720 1.2 PKNOX1 KLF17 RFX5 GTF3C2 SCRT2 FOS RCOR1 EGR2 ELF1 TSHZ1 UPF1 ENSG00000268030 SNORA68 RPL18A MVB12A GTPBP3 HAUS8 ENSG00000268938 KIAA1683 CCDC124
GH19H017703 0.7 ENCODE 11.6 -158.6 -158582 0.2 CTCF ZNF654 TRIM22 SP2 REST RAD21 CC2D1A KLF16 NFYB ZNF143 INSL3 SNORA68 RPL18A PIR50741 MAP1S
GH19H018648 1.5 FANTOM5 Ensembl ENCODE dbSUPER 5.1 +787.6 787571 3.6 CHD1 ZNF266 ZIC2 NR2F2 ZFHX2 POLR2A ZSCAN5C ZNF341 FOS FOXP2 ENSG00000268030 UPF1 ENSG00000268938 NR2C2AP ENSG00000269191 MAU2 KIAA1683 MEF2B ELL CRTC1
GH19H017767 0.5 dbSUPER 11.7 -94.7 -94716 0.9 NFIC NFIB ZBTB40 FCHO1 B3GNT3 UNC13A MAP1S RPL18A SNORA68 INSL3 MVB12A PLVAP GC19M017755
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA68 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA68 Gene

Genomic Locations for SNORA68 Gene
133 bases
Plus strand

Genomic View for SNORA68 Gene

Genes around SNORA68 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA68 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA68 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA68 Gene

ORGUL Member Location for SNORA68 Gene

ORGUL Member Location for SNORA68 gene

Proteins for SNORA68 Gene

Post-translational modifications for SNORA68 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA68 Gene

Domains & Families for SNORA68 Gene

Gene Families for SNORA68 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA68: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA68 Gene

Function for SNORA68 Gene

Phenotypes From GWAS Catalog for SNORA68 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA68 Gene

Localization for SNORA68 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA68 Gene

Pathways & Interactions for SNORA68 Gene

SuperPathways for SNORA68 Gene

No Data Available

Interacting Proteins for SNORA68 Gene

Gene Ontology (GO) - Biological Process for SNORA68 Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA68 Gene

Drugs & Compounds for SNORA68 Gene

No Compound Related Data Available

Transcripts for SNORA68 Gene

mRNA/cDNA for SNORA68 Gene

(2) Additional mRNA sequences :
(2297) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA68 Gene

Small nucleolar RNA, H/ACA box 68:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA68 Gene

No ASD Table

Relevant External Links for SNORA68 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA68 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA68 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA68 Gene:


SOURCE GeneReport for Unigene cluster for SNORA68 Gene:

genes like me logo Genes that share expression patterns with SNORA68: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA68 Gene

Orthologs for SNORA68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA68 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA68 34
  • 98 (a)
(Canis familiaris)
Mammalia SNORA68 34
  • 86 (a)
(Mus musculus)
Mammalia Gm22661 34
  • 74 (a)
(Bos Taurus)
Mammalia SNORA68 34
  • 72 (a)
(Monodelphis domestica)
Mammalia SNORA68 34 34 34
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA68 34 34
  • 64 (a)
(Gallus gallus)
Aves SNORA68 34
  • 62 (a)
(Anolis carolinensis)
Reptilia SNORA68 34
  • 63 (a)
(Danio rerio)
Actinopterygii SNORA68 34 34
  • 61 (a)
Species where no ortholog for SNORA68 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA68 Gene

Gene Tree for SNORA68 (if available)
Gene Tree for SNORA68 (if available)

Paralogs for SNORA68 Gene

No data available for Paralogs for SNORA68 Gene

Variants for SNORA68 Gene

Sequence variations from dbSNP and Humsavar for SNORA68 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000338719 -- 17,861,301(+) CGAGA(C/G)TACAA upstream-variant-2KB, reference, missense
rs1001422649 -- 17,862,035(+) GAGGA(C/T)GGGGC intron-variant, upstream-variant-2KB
rs1001875539 -- 17,862,334(+) GTGGC(A/G)GGGCA intron-variant, upstream-variant-2KB
rs1001941410 -- 17,860,832(+) CTGGG(A/G)AGAGA intron-variant, upstream-variant-2KB
rs1003499292 -- 17,861,101(+) CTCCT(C/T)AGTTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA68 Gene

Variant ID Type Subtype PubMed ID
nsv833772 CNV gain+loss 17160897

Relevant External Links for SNORA68 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA68 Gene

Disorders for SNORA68 Gene

Relevant External Links for SNORA68

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SNORA68 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA68 Gene

Publications for SNORA68 Gene

  1. The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. (PMID: 9106664) Ganot P … Kiss T (Genes & development 1997) 1 2 3 60
  2. Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. (PMID: 9182768) Ganot P … Kiss T (Cell 1997) 1 2 3 60
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 60
  4. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1
  5. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1

Products for SNORA68 Gene

Sources for SNORA68 Gene

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