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Aliases for SNORA68 Gene

Subcategory (RNA class) for SNORA68 Gene

snoRNA

Quality Score for this RNA gene is

11.2

Aliases for SNORA68 Gene

  • Small Nucleolar RNA, H/ACA Box 68 2 3
  • RNA, U68 Small Nucleolar 2 3
  • U68 Small Nucleolar RNA 3
  • U68 SnoRNA 3
  • RNU68 3
  • U68 3

External Ids for SNORA68 Gene

Previous Symbols for SNORA68 Gene

  • RNU68

Summaries for SNORA68 Gene

GeneCards Summary for SNORA68 Gene

SNORA68 (Small Nucleolar RNA, H/ACA Box 68) is a RNA Gene, and belongs to snoRNA RNA class.

fRNAdb sequence ontologies for SNORA68 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA68: U68 is a member of the H/ACA class of small nucleolar RNAs (snoRNAs) which act as guides in the the modification of uridines to pseudouridines [2].

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA68 Gene

Genomics for SNORA68 Gene

Genomic Location for SNORA68 Gene

Start:
17,862,588 bp from pter
End:
17,862,720 bp from pter
Size:
133 bases
Orientation:
Plus strand

Genomic View for SNORA68 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA68 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA68 Gene

Regulatory Elements for SNORA68 Gene

ORGUL Member Location for SNORA68 Gene

ORGUL Member Location for SNORA68 gene

Proteins for SNORA68 Gene

Post-translational modifications for SNORA68 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA68 Gene

Domains for SNORA68 Gene

Gene Families for SNORA68 Gene

HGNC:
  • SNORD :ncRNAs / Small nucleolar RNAs : C/D box containing
genes like me logo Genes that share domains with SNORA68: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for SNORA68 Gene

Function for SNORA68 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA68 Gene

Localization for SNORA68 Gene

No data available for Gene Ontology (GO) - Cellular Components for SNORA68 Gene

Pathways for SNORA68 Gene

SuperPathways for SNORA68 Gene

No Data Available

Interacting Proteins for SNORA68 Gene

Gene Ontology (GO) - Biological Process for SNORA68 Gene

None

No data available for Pathways by source for SNORA68 Gene

Transcripts for SNORA68 Gene

mRNA/cDNA for SNORA68 Gene

(2) Additional mRNA sequences :
(2297) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA68 Gene

Small nucleolar RNA, H/ACA box 68:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA68 Gene

No ASD Table

Relevant External Links for SNORA68 Gene

GeneLoc Exon Structure for
SNORA68
ECgene alternative splicing isoforms for
SNORA68

Expression for SNORA68 Gene

mRNA expression in normal human tissues for SNORA68 Gene

SOURCE GeneReport for Unigene cluster for SNORA68 Gene Hs.684118

genes like me logo Genes that share expressions with SNORA68: view

Orthologs for SNORA68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA68 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA68 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA68 37
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA68 37
  • 86 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm22661 37
  • 74 (a)
ManyToMany
Snora68 16
oppossum
(Monodelphis domestica)
Mammalia SNORA68 37
  • 66 (a)
ManyToMany
SNORA68 37
  • 68 (a)
ManyToMany
SNORA68 37
  • 57 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA68 37
  • 64 (a)
ManyToMany
SNORA68 37
  • 53 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA68 37
  • 62 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA68 37
  • 63 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA68 37
  • 61 (a)
ManyToMany
SNORA68 37
  • 61 (a)
ManyToMany
Species with no ortholog for SNORA68:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA68 Gene

ENSEMBL:
Gene Tree for SNORA68 (if available)
TreeFam:
Gene Tree for SNORA68 (if available)

Paralogs for SNORA68 Gene

No data available for Paralogs for SNORA68 Gene

Variants for SNORA68 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA68 Gene

Variant ID Type Subtype PubMed ID
nsv911209 CNV Loss 21882294
nsv911214 CNV Loss 21882294
nsv911219 CNV Loss 21882294
dgv3766n71 CNV Loss 21882294
nsv833772 CNV Gain+Loss 17160897

Relevant External Links for SNORA68 Gene

HapMap Linkage Disequilibrium report
SNORA68

No data available for Sequence variations from dbSNP and Humsavar for SNORA68 Gene

Disorders for SNORA68 Gene

No disorders were found for SNORA68 Gene.

No data available for UniProtKB/Swiss-Prot for SNORA68 Gene

Publications for SNORA68 Gene

  1. The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. (PMID: 9106664) Ganot P. … Kiss T. (Genes Dev. 1997) 2 3
  2. Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. (PMID: 9182768) Ganot P. … Kiss T. (Cell 1997) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3

Products for SNORA68 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA68
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA68
    • Block miRNA regulation of SNORA68 using miScript Target Protectors

    Sources for SNORA68 Gene

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