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Aliases for SNORA66 Gene

Subcategory (RNA class) for SNORA66 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA66 Gene

  • Small Nucleolar RNA, H/ACA Box 66 2 3 5
  • RNA, U66 Small Nucleolar 2 3
  • RNU66 3
  • U66 3

External Ids for SNORA66 Gene

ORGUL Members for SNORA66 Gene

Previous HGNC Symbols for SNORA66 Gene

  • RNU66

Previous GeneCards Identifiers for SNORA66 Gene

  • GC01P093078
  • GC01P093306
  • GC01P091427

Summaries for SNORA66 Gene

Entrez Gene Summary for SNORA66 Gene

  • This gene encodes a non-coding RNA that functions in the biogenesis of other small nuclear RNAs. This RNA is found in the nucleolus, where it may be involved in the pseudouridylation of 18S ribosomal RNA. This RNA is found associated with the GAR1 protein. [provided by RefSeq, Apr 2009]

GeneCards Summary for SNORA66 Gene

SNORA66 (Small Nucleolar RNA, H/ACA Box 66) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA66 Gene

Genomics for SNORA66 Gene

Regulatory Elements for SNORA66 Gene

Enhancers for SNORA66 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F093078 1.2 ENCODE 59.4 +239.7 239717 4.5 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 CCDC18-AS1 SNORA66 SNORD21 RPL5 DNTTIP2 DR1 LOC100289500 ACTBP12 MTCO3P21 ENSG00000230439
GH01F093811 1.3 Ensembl ENCODE 50 +974.5 974541 8.3 PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 ZNF48 ZNF2 ZNF143 DEK ENSG00000230439 SNORA66 CCDC18-AS1 SNORD21 RPL5 TRR-TCT1-1 DR1 BCAR3 MIR760 DNTTIP2
GH01F093177 1.2 ENCODE 51.5 +339.3 339305 4.7 PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF302 ZNF416 CCDC18-AS1 SNORA66 SNORD21 RPL5 DNTTIP2 LOC100289500 MTCO3P21 ACTBP12 ENSG00000233482 DR1
GH01F092831 1.2 ENCODE 48 -7.3 -7291 4.2 CREB3L1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 SNORA66 SNORD21 CCDC18-AS1 ENSG00000230439 RPL5 LOC100289500 ACTBP12 DR1 FAM69A GC01P092832
GH01F092803 1.5 FANTOM5 Ensembl ENCODE 37.4 -35.7 -35662 3.1 PKNOX1 ATF1 ARNT CREB3L1 GTF3C2 ZNF121 GATA2 FOS NFYC NCOA1 SNORD21 SNORA66 CCDC18-AS1 RPL5 DR1 RPAP2 EVI5 GC01M092807
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA66 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA66 Gene

Chromosome:
1
Start:
92,840,719 bp from pter
End:
92,840,851 bp from pter
Size:
133 bases
Orientation:
Plus strand

Genomic View for SNORA66 Gene

Genes around SNORA66 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA66 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA66 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA66 Gene

Proteins for SNORA66 Gene

Post-translational modifications for SNORA66 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA66 Gene

Domains & Families for SNORA66 Gene

Gene Families for SNORA66 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA66: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA66 Gene

Function for SNORA66 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA66 Gene

Localization for SNORA66 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA66 Gene

Pathways & Interactions for SNORA66 Gene

SuperPathways for SNORA66 Gene

No Data Available

Interacting Proteins for SNORA66 Gene

Gene Ontology (GO) - Biological Process for SNORA66 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA66 Gene

Transcripts for SNORA66 Gene

mRNA/cDNA for SNORA66 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA66 Gene

No ASD Table

Relevant External Links for SNORA66 Gene

GeneLoc Exon Structure for
SNORA66
ECgene alternative splicing isoforms for
SNORA66

Expression for SNORA66 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORA66 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA66 Gene:

SNORA66
genes like me logo Genes that share expression patterns with SNORA66: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORA66 Gene

Orthologs for SNORA66 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA66 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA66 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA66 35
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA66 35
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm26387 35
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA66 35
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA66 35
  • 70 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA66 35
  • 52 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORA66 35
  • 72 (a)
OneToMany
Species where no ortholog for SNORA66 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA66 Gene

ENSEMBL:
Gene Tree for SNORA66 (if available)
TreeFam:
Gene Tree for SNORA66 (if available)

Paralogs for SNORA66 Gene

No data available for Paralogs for SNORA66 Gene

Variants for SNORA66 Gene

Sequence variations from dbSNP and Humsavar for SNORA66 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10874744 -- 92,840,760(+) GAAGC(A/G)AAGGG intron-variant, nc-transcript-variant
rs111307161 -- 92,840,008(+) GCTAA(-/T)TTTTT intron-variant, upstream-variant-2KB
rs111607814 -- 92,840,904(+) GTTGA(A/T)CTTTC intron-variant, downstream-variant-500B
rs114907162 -- 92,840,972(+) GTGAT(A/G)TGATG intron-variant, downstream-variant-500B
rs11586570 -- 92,839,814(+) CTCAG(A/C)AGTAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA66 Gene

Variant ID Type Subtype PubMed ID
nsv508393 CNV deletion 20534489
nsv1008602 CNV gain 25217958
esv2714684 CNV deletion 23290073

Relevant External Links for SNORA66 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA66

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA66 Gene

Disorders for SNORA66 Gene

Relevant External Links for SNORA66

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA66

No disorders were found for SNORA66 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA66 Gene

Publications for SNORA66 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3 64
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3 64
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORA66 Gene

Sources for SNORA66 Gene

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