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Aliases for SNORA62 Gene

Subcategory (RNA class) for SNORA62 Gene

snoRNA

Quality Score for this RNA gene is

12

Aliases for SNORA62 Gene

  • Small Nucleolar RNA, H/ACA Box 62 2 3 5
  • RNA, U108 Small Nucleolar 2 3
  • RNA, Small Nucleolar E2 3
  • RNU108 3
  • E2-1 3
  • RNE2 3
  • E2 3

External Ids for SNORA62 Gene

Previous HGNC Symbols for SNORA62 Gene

  • RNE2
  • RNU108

Previous GeneCards Identifiers for SNORA62 Gene

  • GC03P039430
  • GC03P039432
  • GC03P039450
  • GC03P039454
  • GC03P039458
  • GC03P039460
  • GC03P039466
  • GC03P039479
  • GC03P039437
  • GC03P039441

Summaries for SNORA62 Gene

GeneCards Summary for SNORA62 Gene

SNORA62 (Small Nucleolar RNA, H/ACA Box 62) is an RNA Gene, and is affiliated with the snoRNA class. Among its related pathways are Alpha6-Beta4 Integrin Signaling Pathway and Viral mRNA Translation.

fRNAdb sequence ontologies for SNORA62 Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA62/SNORA6 family: The members of this family belong to the H/ACA class of snoRNAs which are predicted to guide the sites of modification of uridines to pseudouridines [3]. This family includes human snoRNAs E2 (SNORA62), ACA6 (SNORA6) and M2 and mouse MBI-136. In humans both E2 and ACA6 are encoded in the introns on the same host gene (LAMR1)[1,3]. E2 is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 28S rRNA [2]. ACA6 is predicted to guide the pseudouridylation of residue U3616 of 28S rRNA [5].

View fRNAdb secondary structures for SNORA62

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA62 Gene

Genomics for SNORA62 Gene

Regulatory Elements for SNORA62 Gene

Genomic Location for SNORA62 Gene

Chromosome:
3
Start:
39,411,054 bp from pter
End:
39,411,207 bp from pter
Size:
154 bases
Orientation:
Plus strand

Genomic View for SNORA62 Gene

Genes around SNORA62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA62 Gene

ORGUL Member Location for SNORA62 Gene

ORGUL Member Location for SNORA62 gene

Proteins for SNORA62 Gene

Post-translational modifications for SNORA62 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA62 Gene

Domains & Families for SNORA62 Gene

Gene Families for SNORA62 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA62: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA62 Gene

Function for SNORA62 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA62 Gene

Localization for SNORA62 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA62 Gene

Pathways & Interactions for SNORA62 Gene

genes like me logo Genes that share pathways with SNORA62: view

Pathways by source for SNORA62 Gene

Interacting Proteins for SNORA62 Gene

Gene Ontology (GO) - Biological Process for SNORA62 Gene

None

No data available for SIGNOR curated interactions for SNORA62 Gene

Drugs & Compounds for SNORA62 Gene

No Compound Related Data Available

Transcripts for SNORA62 Gene

fRNAdb Secondary structures for SNORA62 Gene

  • FR143100

mRNA/cDNA for SNORA62 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA62 Gene

No ASD Table

Relevant External Links for SNORA62 Gene

GeneLoc Exon Structure for
SNORA62
ECgene alternative splicing isoforms for
SNORA62

Expression for SNORA62 Gene

mRNA expression in normal human tissues for SNORA62 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB for SNORA62 Gene



genes like me logo Genes that share expression patterns with SNORA62: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SNORA62 Gene

Orthologs for SNORA62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA62 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA62 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA62 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snora62 36
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA62 36
  • 84 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA62 36
  • 70 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA62 36
  • 71 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA62 36
  • 74 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA62 36
  • 52 (a)
OneToMany
Species with no ortholog for SNORA62:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA62 Gene

ENSEMBL:
Gene Tree for SNORA62 (if available)
TreeFam:
Gene Tree for SNORA62 (if available)

Paralogs for SNORA62 Gene

No data available for Paralogs for SNORA62 Gene

Variants for SNORA62 Gene

Relevant External Links for SNORA62 Gene

HapMap Linkage Disequilibrium report
SNORA62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA62 Gene

Disorders for SNORA62 Gene

Relevant External Links for SNORA62

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA62

No disorders were found for SNORA62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA62 Gene

Publications for SNORA62 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1 2 3 67
  2. Three small nucleolar RNAs of unique nucleotide sequences. (PMID: 8421699) Ruff E.A. … Eliceiri G.L. (Proc. Natl. Acad. Sci. U.S.A. 1993) 1 2 3
  3. Genes for E1, E2, and E3 small nucleolar RNAs. (PMID: 8415643) Nag M.K. … Eliceiri G.L. (Proc. Natl. Acad. Sci. U.S.A. 1993) 2 3
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  5. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) . … Gojobori T. (Nucleic Acids Res. 2008) 1

Products for SNORA62 Gene

Sources for SNORA62 Gene

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