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Aliases for SNORA62 Gene

Subcategory (RNA class) for SNORA62 Gene

snoRNA

Quality Score for this RNA gene is

11

Aliases for SNORA62 Gene

  • Small Nucleolar RNA, H/ACA Box 62 2 3
  • RNA, U108 Small Nucleolar 2 3
  • RNU108 3 6
  • RNE2 3 6
  • RNA, Small Nucleolar E2 3
  • E2-1 3
  • E2 3

External Ids for SNORA62 Gene

Previous Symbols for SNORA62 Gene

  • RNE2
  • RNU108

Summaries for SNORA62 Gene

GeneCards Summary for SNORA62 Gene

SNORA62 (Small Nucleolar RNA, H/ACA Box 62) is a RNA Gene, and belongs to snoRNA RNA class. Among its related pathways are Alpha6-Beta4 Integrin Signaling Pathway and CFTR translational fidelity (class I mutations).

fRNAdb sequence ontologies for SNORA62 Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA62/SNORA6 family: The members of this family belong to the H/ACA class of snoRNAs which are predicted to guide the sites of modification of uridines to pseudouridines [3]. This family includes human snoRNAs E2 (SNORA62), ACA6 (SNORA6) and M2 and mouse MBI-136. In humans both E2 and ACA6 are encoded in the introns on the same host gene (LAMR1)[1,3]. E2 is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 28S rRNA [2]. ACA6 is predicted to guide the pseudouridylation of residue U3616 of 28S rRNA [5].

View fRNAdb secondary structures for SNORA62

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA62 Gene

Genomics for SNORA62 Gene

Genomic Location for SNORA62 Gene

Start:
39,411,054 bp from pter
End:
39,411,207 bp from pter
Size:
154 bases
Orientation:
Plus strand

Genomic View for SNORA62 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA62 Gene

Regulatory Elements for SNORA62 Gene

ORGUL Member Location for SNORA62 Gene

ORGUL Member Location for SNORA62 gene

Proteins for SNORA62 Gene

Post-translational modifications for SNORA62 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA62 Gene

Domains for SNORA62 Gene

Gene Families for SNORA62 Gene

HGNC:
  • SNORD :ncRNAs / Small nucleolar RNAs : C/D box containing
genes like me logo Genes that share domains with SNORA62: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for SNORA62 Gene

Function for SNORA62 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA62 Gene

Localization for SNORA62 Gene

No data available for Gene Ontology (GO) - Cellular Components for SNORA62 Gene

Pathways for SNORA62 Gene

genes like me logo Genes that share pathways with SNORA62: view

Pathways by source for SNORA62 Gene

Interacting Proteins for SNORA62 Gene

Gene Ontology (GO) - Biological Process for SNORA62 Gene

None

Transcripts for SNORA62 Gene

fRNAdb Secondary structures for SNORA62 Gene

  • FR143100

mRNA/cDNA for SNORA62 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA62 Gene

No ASD Table

Relevant External Links for SNORA62 Gene

GeneLoc Exon Structure for
SNORA62
ECgene alternative splicing isoforms for
SNORA62

Expression for SNORA62 Gene

mRNA expression in normal human tissues for SNORA62 Gene

Integrated Proteomics: protein expression from MaxQB for SNORA62 Gene

genes like me logo Genes that share expressions with SNORA62: view

Orthologs for SNORA62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA62 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA62 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA62 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snora62 16
Snora62 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA62 37
  • 84 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA62 37
  • 70 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA62 37
  • 71 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA62 37
  • 74 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA62 37
  • 52 (a)
OneToMany
Species with no ortholog for SNORA62:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA62 Gene

ENSEMBL:
Gene Tree for SNORA62 (if available)
TreeFam:
Gene Tree for SNORA62 (if available)

Paralogs for SNORA62 Gene

No data available for Paralogs for SNORA62 Gene

Variants for SNORA62 Gene

Relevant External Links for SNORA62 Gene

HapMap Linkage Disequilibrium report
SNORA62

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SNORA62 Gene

Disorders for SNORA62 Gene

No disorders were found for SNORA62 Gene.

No data available for UniProtKB/Swiss-Prot for SNORA62 Gene

Publications for SNORA62 Gene

  1. Genes for E1, E2, and E3 small nucleolar RNAs. (PMID: 8415643) Nag M.K. … Eliceiri G.L. (Proc. Natl. Acad. Sci. U.S.A. 1993) 2 3
  2. Three small nucleolar RNAs of unique nucleotide sequences. (PMID: 8421699) Ruff E.A. … Eliceiri G.L. (Proc. Natl. Acad. Sci. U.S.A. 1993) 2 3
  3. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  5. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PMID: 23862649) Leng L. … Wang J. (J. Proteome Res. 2014) 3

Products for SNORA62 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA62
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA62
    • Block miRNA regulation of SNORA62 using miScript Target Protectors

    Sources for SNORA62 Gene

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