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Aliases for SNORA5C Gene

Subcategory (RNA class) for SNORA5C Gene

snoRNA

Quality Score for this RNA gene is

6

Aliases for SNORA5C Gene

  • Small Nucleolar RNA, H/ACA Box 5C 2 3
  • HBI-80 3
  • ACA5c 3

External Ids for SNORA5C Gene

ORGUL Members for SNORA5C Gene

Previous GeneCards Identifiers for SNORA5C Gene

  • GC07M045111
  • GC07M045144
  • GC07M045028

Summaries for SNORA5C Gene

Entrez Gene Summary for SNORA5C Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA5C, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA5C Gene

SNORA5C (Small Nucleolar RNA, H/ACA Box 5C) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA5C Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

  • Small nucleolar RNA SNORA5: ACA5 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

  • Small nucleolar RNA SNORA5: ACA5 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA5C Gene

Genomics for SNORA5C Gene

Regulatory Elements for SNORA5C Gene

Genomic Location for SNORA5C Gene

Start:
45,104,906 bp from pter
End:
45,105,042 bp from pter
Size:
137 bases
Orientation:
Minus strand

Genomic View for SNORA5C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA5C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA5C Gene

ORGUL Member Location for SNORA5C Gene

ORGUL Member Location for SNORA5C gene

Proteins for SNORA5C Gene

Post-translational modifications for SNORA5C Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA5C Gene

Domains for SNORA5C Gene

Gene Families for SNORA5C Gene

HGNC:
  • SNORA :ncRNAs / Small nucleolar RNAs : H/ACA box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA5C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA5C Gene

Function for SNORA5C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA5C Gene

Localization for SNORA5C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA5C Gene

Pathways for SNORA5C Gene

SuperPathways for SNORA5C Gene

No Data Available

Interacting Proteins for SNORA5C Gene

Gene Ontology (GO) - Biological Process for SNORA5C Gene

None

No data available for Pathways by source for SNORA5C Gene

Transcripts for SNORA5C Gene

mRNA/cDNA for SNORA5C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA5C Gene

No ASD Table

Relevant External Links for SNORA5C Gene

GeneLoc Exon Structure for
SNORA5C
ECgene alternative splicing isoforms for
SNORA5C

Expression for SNORA5C Gene

mRNA expression in normal human tissues for SNORA5C Gene

SOURCE GeneReport for Unigene cluster for SNORA5C Gene Hs.692718

genes like me logo Genes that share expressions with SNORA5C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SNORA5C Gene

Orthologs for SNORA5C Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA5C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA5 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA5 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA5 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snora5c 16
Snora5c 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA5 36
  • 69 (a)
ManyToMany
SNORA5 36
  • 70 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA5 36
  • 66 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA5 36
  • 64 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORA5 36
  • 62 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA5 36
  • 56 (a)
ManyToMany
SNORA5 36
  • 55 (a)
ManyToMany
SNORA5 36
  • 54 (a)
ManyToMany
SNORA5 36
  • 54 (a)
ManyToMany
Species with no ortholog for SNORA5C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA5C Gene

ENSEMBL:
Gene Tree for SNORA5C (if available)
TreeFam:
Gene Tree for SNORA5C (if available)

Paralogs for SNORA5C Gene

No data available for Paralogs for SNORA5C Gene

Variants for SNORA5C Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA5C Gene

Variant ID Type Subtype PubMed ID
nsv888001 CNV Loss 21882294

Relevant External Links for SNORA5C Gene

HapMap Linkage Disequilibrium report
SNORA5C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for SNORA5C Gene

Disorders for SNORA5C Gene

No disorders were found for SNORA5C Gene.

No data available for UniProtKB/Swiss-Prot for SNORA5C Gene

Publications for SNORA5C Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3
  3. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu A.D. … Qu L.H. (Nucleic Acids Res. 2005) 3
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3

Products for SNORA5C Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA5C
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA5C
    • Block miRNA regulation of SNORA5C using miScript Target Protectors

    Sources for SNORA5C Gene

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