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Aliases for SNORA5B Gene

Subcategory (RNA class) for SNORA5B Gene

snoRNA

Quality Score for this RNA gene is

7

Aliases for SNORA5B Gene

  • Small Nucleolar RNA, H/ACA Box 5B 2 3 5
  • ACA5b 3

External Ids for SNORA5B Gene

ORGUL Members for SNORA5B Gene

Previous GeneCards Identifiers for SNORA5B Gene

  • GC07M045112
  • GC07M045145
  • GC07M045029
  • GC07M045109
  • GC07M045116
  • GC07M045123
  • GC07M045127
  • GC07M045131
  • GC07M045135

Summaries for SNORA5B Gene

GeneCards Summary for SNORA5B Gene

SNORA5B (Small Nucleolar RNA, H/ACA Box 5B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA5B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA5: ACA5 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

Additional gene information for SNORA5B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA5B Gene

Genomics for SNORA5B Gene

Regulatory Elements for SNORA5B Gene

Enhancers for SNORA5B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H044628 2 FANTOM5 Ensembl ENCODE dbSUPER 19.3 +470.9 470895 13 HDGF PKNOX1 SIN3A FEZF1 YY1 ZNF766 ZNF143 FOS DEK JUNB DDX56 OGDH H2AFV SNORA5C PURB SNORA5B NACAD NUDCD3 TMED4 ENSG00000228434
GH07H044121 1.1 ENCODE 29.3 +983.1 983060 3 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS ENSG00000228680 DDX56 POLM TMED4 SPDYE1 SNORA5B ENSG00000228434 SNORA5C SNHG15 TBRG4
GH07H044184 1.1 ENCODE dbSUPER 26.1 +921.1 921063 1 YBX3 SIN3A KLF17 GLI4 RFX5 ZNF366 SCRT2 RCOR1 FOS ZNF645 ENSG00000228680 POLM SNORA5C DDX56 SNORA5B TMED4 SNORA5A ENSG00000228596 RPL18AP10 ENSG00000228434
GH07H044845 1.2 ENCODE 22.6 +258.5 258516 4 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 CICP20 DDX56 SPDYE1 SNORA5C POLM SNORA5B SNHG15 ENSG00000228434 TMED4 URGCP
GH07H044613 1.9 FANTOM5 Ensembl ENCODE dbSUPER 13 +485.7 485708 13 HDGF FOXA2 ATF1 FEZF1 DMAP1 GTF3C2 ZNF121 FOS ATF7 RUNX3 PURB DDX56 ZMIZ2 SNORA5C POLM ENSG00000228434 SNORA5B URGCP SNORA5A TMED4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA5B on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA5B Gene

Chromosome:
7
Start:
45,105,968 bp from pter
End:
45,106,099 bp from pter
Size:
132 bases
Orientation:
Minus strand

Genomic View for SNORA5B Gene

Genes around SNORA5B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA5B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA5B Gene

ORGUL Member Location for SNORA5B Gene

ORGUL Member Location for SNORA5B gene

Proteins for SNORA5B Gene

Post-translational modifications for SNORA5B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA5B Gene

Domains & Families for SNORA5B Gene

Gene Families for SNORA5B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA5B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA5B Gene

Function for SNORA5B Gene

Phenotypes From GWAS Catalog for SNORA5B Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for SNORA5B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA5B Gene

Localization for SNORA5B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA5B Gene

Pathways & Interactions for SNORA5B Gene

SuperPathways for SNORA5B Gene

No Data Available

Interacting Proteins for SNORA5B Gene

Gene Ontology (GO) - Biological Process for SNORA5B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA5B Gene

Drugs & Compounds for SNORA5B Gene

No Compound Related Data Available

Transcripts for SNORA5B Gene

mRNA/cDNA for SNORA5B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for SNORA5B
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA5B Gene

No ASD Table

Relevant External Links for SNORA5B Gene

GeneLoc Exon Structure for
SNORA5B
ECgene alternative splicing isoforms for
SNORA5B

Expression for SNORA5B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA5B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA5B Gene:

SNORA5B

SOURCE GeneReport for Unigene cluster for SNORA5B Gene:

Hs.693124
genes like me logo Genes that share expression patterns with SNORA5B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA5B Gene

Orthologs for SNORA5B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA5B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA5 34
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA5 34
  • 75 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm23346 34
  • 68 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia SNORA5 34
  • 65 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA5 34
  • 64 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA5 34
  • 56 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORA5 34
  • 59 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA5 34 34 34 34
  • 61 (a)
ManyToMany
Species where no ortholog for SNORA5B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA5B Gene

ENSEMBL:
Gene Tree for SNORA5B (if available)
TreeFam:
Gene Tree for SNORA5B (if available)

Paralogs for SNORA5B Gene

No data available for Paralogs for SNORA5B Gene

Variants for SNORA5B Gene

Sequence variations from dbSNP and Humsavar for SNORA5B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000692262 -- 45,106,011(+) CAGTA(A/G)CAGGG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1001520861 -- 45,105,646(+) GCTTC(C/T)GCATG downstream-variant-500B, upstream-variant-2KB, reference, missense
rs1003254103 -- 45,106,340(+) CCTGG(C/T)TACAG intron-variant, upstream-variant-2KB
rs1004852002 -- 45,106,943(+) TGCAG(C/T)GCGTT intron-variant, upstream-variant-2KB
rs1009415469 -- 45,107,362(+) GGTAA(C/T)TGCTA intron-variant, upstream-variant-2KB

Relevant External Links for SNORA5B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA5B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA5B Gene

Disorders for SNORA5B Gene

Relevant External Links for SNORA5B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA5B

No disorders were found for SNORA5B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA5B Gene

Publications for SNORA5B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1 2 3 60
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 1 2 3 60
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 60
  4. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang KC … Mattick JS (Nucleic acids research 2005) 1

Products for SNORA5B Gene

Sources for SNORA5B Gene

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