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Aliases for SNORA5B Gene

Subcategory (RNA class) for SNORA5B Gene

snoRNA

Quality Score for this RNA gene is

7

Aliases for SNORA5B Gene

  • Small Nucleolar RNA, H/ACA Box 5B 2 3 5
  • ACA5b 3

External Ids for SNORA5B Gene

ORGUL Members for SNORA5B Gene

Previous GeneCards Identifiers for SNORA5B Gene

  • GC07M045112
  • GC07M045145
  • GC07M045029
  • GC07M045109
  • GC07M045116
  • GC07M045123
  • GC07M045127

Summaries for SNORA5B Gene

GeneCards Summary for SNORA5B Gene

SNORA5B (Small Nucleolar RNA, H/ACA Box 5B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA5B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA5: ACA5 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA5B Gene

Genomics for SNORA5B Gene

Regulatory Elements for SNORA5B Gene

Enhancers for SNORA5B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F044613 1.6 FANTOM5 Ensembl ENCODE 13.2 +485.7 485708 13.0 HDGF ATF1 WRNIP1 FEZF1 DMAP1 GTF3C2 ZNF121 FOS JUNB MIER3 PURB DDX56 ZMIZ2 SNORA5C ENSG00000228434 SNORA5B SNORA5A ENSG00000228596 TBRG4 MYO1G
GH07F044121 1.1 ENCODE 18.6 +983.1 983060 3.4 HDGF PKNOX1 MLX WRNIP1 ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF143 ENSG00000228680 SNORA5B RPL18AP10 ENSG00000228596 MIR3943 DDX56 SNORA5C NACAD POLR2J4 GCK
GH07F044733 1.4 FANTOM5 Ensembl ENCODE 13.2 +370.6 370625 4.1 KLF17 SIN3A RAD21 RFX5 GTF3C2 ZNF121 SCRT2 FOS CREM EGR2 PURB SNORA5C DDX56 ENSG00000228434 SNORA5B SNORA5A MYO1G TBRG4 POLR2J4 ZMIZ2
GH07F044184 1.1 Ensembl ENCODE 15.3 +921.1 921063 1.8 YBX3 KLF17 SIN3A GLI4 RFX5 GLIS2 ZNF366 SCRT2 RCOR1 FOS ENSG00000228680 ENSG00000228596 RPL18AP10 SNORA5B SNORA5C ENSG00000228434 SPDYE1 TBRG4 DDX56 YKT6
GH07F044754 1.4 Ensembl ENCODE 11.7 +350.1 350090 4.0 HDGF PKNOX1 MLX CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ENSG00000228596 ELK1P1 SNORA5C SNORA5B DDX56 SNHG15 GC07M044752 PIR36062
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA5B on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA5B Gene

Chromosome:
7
Start:
45,105,968 bp from pter
End:
45,106,099 bp from pter
Size:
132 bases
Orientation:
Minus strand

Genomic View for SNORA5B Gene

Genes around SNORA5B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA5B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA5B Gene

ORGUL Member Location for SNORA5B Gene

ORGUL Member Location for SNORA5B gene

Proteins for SNORA5B Gene

Post-translational modifications for SNORA5B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA5B Gene

Domains & Families for SNORA5B Gene

Gene Families for SNORA5B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA5B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA5B Gene

Function for SNORA5B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA5B Gene

Localization for SNORA5B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA5B Gene

Pathways & Interactions for SNORA5B Gene

SuperPathways for SNORA5B Gene

No Data Available

Interacting Proteins for SNORA5B Gene

Gene Ontology (GO) - Biological Process for SNORA5B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA5B Gene

Transcripts for SNORA5B Gene

mRNA/cDNA for SNORA5B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA5B Gene

No ASD Table

Relevant External Links for SNORA5B Gene

GeneLoc Exon Structure for
SNORA5B
ECgene alternative splicing isoforms for
SNORA5B

Expression for SNORA5B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORA5B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA5B Gene:

SNORA5B

SOURCE GeneReport for Unigene cluster for SNORA5B Gene:

Hs.693124
genes like me logo Genes that share expression patterns with SNORA5B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORA5B Gene

Orthologs for SNORA5B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA5B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA5 35
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA5 35
  • 75 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm23346 35
  • 68 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia SNORA5 35
  • 65 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA5 35
  • 64 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA5 35
  • 56 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia SNORA5 35
  • 59 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA5 35 35 35 35
  • 61 (a)
ManyToMany
Species where no ortholog for SNORA5B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA5B Gene

ENSEMBL:
Gene Tree for SNORA5B (if available)
TreeFam:
Gene Tree for SNORA5B (if available)

Paralogs for SNORA5B Gene

No data available for Paralogs for SNORA5B Gene

Variants for SNORA5B Gene

Sequence variations from dbSNP and Humsavar for SNORA5B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs112916426 -- 45,105,522(+) TCTTC(A/C/T)ATTTC downstream-variant-500B, upstream-variant-2KB, reference, synonymous-codon, missense
rs113885365 -- 45,106,376(+) CAGCT(C/G/T)CAAGT intron-variant, upstream-variant-2KB
rs117131517 -- 45,107,692(+) CAGGA(A/C)AATCT intron-variant, upstream-variant-2KB
rs137899623 -- 45,105,600(+) AGGGT(A/G)GCACA downstream-variant-500B, upstream-variant-2KB, reference, synonymous-codon
rs139255897 -- 45,105,733(+) GCAGC(C/T)TCGAG downstream-variant-500B, upstream-variant-2KB, reference, missense

Relevant External Links for SNORA5B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA5B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA5B Gene

Disorders for SNORA5B Gene

Relevant External Links for SNORA5B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA5B

No disorders were found for SNORA5B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA5B Gene

Publications for SNORA5B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1 2 3 64
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 1 2 3 64
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64
  4. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang K.C. … Mattick J.S. (Nucleic Acids Res. 2005) 1

Products for SNORA5B Gene

Sources for SNORA5B Gene

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