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Aliases for SNORA53 Gene

Subcategory (RNA class) for SNORA53 Gene

snoRNA

Quality Score for this RNA gene is

3.2

Aliases for SNORA53 Gene

  • Small Nucleolar RNA, H/ACA Box 53 2 3 5
  • ACA53 3

External Ids for SNORA53 Gene

Previous GeneCards Identifiers for SNORA53 Gene

  • GC12P097517
  • GC12P098993
  • GC12P096054

Summaries for SNORA53 Gene

GeneCards Summary for SNORA53 Gene

SNORA53 (Small Nucleolar RNA, H/ACA Box 53) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA53 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

Additional gene information for SNORA53 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA53 Gene

Genomics for SNORA53 Gene

Regulatory Elements for SNORA53 Gene

Enhancers for SNORA53 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H098532 0.9 ENCODE 10.3 -66.1 -66058 1 HDAC1 PKNOX1 ARNT RAD21 ZNF766 ZNF143 ATF7 SMARCA5 CEBPB ZEB2 RNU4-41P LINC02453 SNORA53 APAF1 IKBIP SLC9A7P1 GC12M098524 GC12M098549
GH12H098635 0.8 ENCODE 10.9 +36.6 36550 0 PKNOX1 JUN INSM2 FEZF1 BATF ZEB1 ZNF366 ZSCAN5C FOS ZNF600 SLC25A3 PPIAP8 SNORA53 IKBIP GC12M098601
GH12H098654 0.7 ENCODE 11.3 +54.5 54453 0 CTCF FOXA2 ARID4B RAD21 RFX5 FOXK2 SMC3 ZNF143 MIXL1 SMARCA5 SNORA53 RNU4-41P LINC02453 IKBIP GC12P098649 GC12M098651
GH12H098351 0.9 Ensembl ENCODE 4.8 -246.9 -246893 2 ZBTB21 JUN EBF1 DPF2 ZBTB40 ZEB1 JUND IKZF1 FOS ATF7 SNORA53 LOC105369933 GC12P098384
GH12H098650 0.3 FANTOM5 10.1 +50.7 50727 0 IKBIP SLC25A3 PPIAP8 SNORA53 LINC02453 GC12P098649 GC12M098651
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA53 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA53 Gene

Chromosome:
12
Start:
98,599,635 bp from pter
End:
98,599,884 bp from pter
Size:
250 bases
Orientation:
Plus strand

Genomic View for SNORA53 Gene

Genes around SNORA53 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA53 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA53 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA53 Gene

ORGUL Member Location for SNORA53 Gene

ORGUL Member Location for SNORA53 gene

Proteins for SNORA53 Gene

Post-translational modifications for SNORA53 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA53 Gene

Domains & Families for SNORA53 Gene

Gene Families for SNORA53 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA53: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA53 Gene

Function for SNORA53 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for SNORA53
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA53 Gene

Localization for SNORA53 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA53 Gene

Pathways & Interactions for SNORA53 Gene

SuperPathways for SNORA53 Gene

No Data Available

Interacting Proteins for SNORA53 Gene

Gene Ontology (GO) - Biological Process for SNORA53 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA53 Gene

Drugs & Compounds for SNORA53 Gene

No Compound Related Data Available

Transcripts for SNORA53 Gene

mRNA/cDNA for SNORA53 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for SNORA53
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA53 Gene

No ASD Table

Relevant External Links for SNORA53 Gene

GeneLoc Exon Structure for
SNORA53
ECgene alternative splicing isoforms for
SNORA53

Expression for SNORA53 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA53 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA53 Gene:

SNORA53

SOURCE GeneReport for Unigene cluster for SNORA53 Gene:

Hs.693250
genes like me logo Genes that share expression patterns with SNORA53: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA53 Gene

Orthologs for SNORA53 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA53 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA53 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA53 34
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA53 34
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm24119 34
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA53 34
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA53 34
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA53 34
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORA53 34
  • 74 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii SNORA53 34 34
  • 51 (a)
OneToMany
Species where no ortholog for SNORA53 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA53 Gene

ENSEMBL:
Gene Tree for SNORA53 (if available)
TreeFam:
Gene Tree for SNORA53 (if available)

Paralogs for SNORA53 Gene

No data available for Paralogs for SNORA53 Gene

Variants for SNORA53 Gene

Sequence variations from dbSNP and Humsavar for SNORA53 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs11544648 Likely benign 98,598,012(+) AAGTC(C/T)TGTAT upstream-variant-2KB, reference, synonymous-codon
rs200029342 Uncertain significance 98,600,132(+) GGTAC(A/C/G/T)AATTA intron-variant, downstream-variant-500B
rs531425336 Uncertain significance 98,598,533(+) ACTTA(C/T)CTCTG upstream-variant-2KB, reference, synonymous-codon
rs772819565 Uncertain significance 98,600,028(+) TTGAA(C/T)GTACT downstream-variant-500B, reference, missense
rs886049920 Uncertain significance 98,600,131(+) AGGTA(C/T)GAATT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for SNORA53 Gene

Variant ID Type Subtype PubMed ID
nsv559918 CNV loss 21841781
nsv7234 OTHER inversion 18451855

Relevant External Links for SNORA53 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA53

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA53 Gene

Disorders for SNORA53 Gene

Relevant External Links for SNORA53

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA53

No disorders were found for SNORA53 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA53 Gene

Publications for SNORA53 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 60
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 60
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 60
  4. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang KC … Mattick JS (Nucleic acids research 2005) 1
  5. Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome. (PMID: 16273071) Washietl S … Stadler PF (Nature biotechnology 2005) 1

Products for SNORA53 Gene

Sources for SNORA53 Gene

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