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Aliases for SNORA50D Gene

Subcategory (RNA class) for SNORA50D Gene

snoRNA

Quality Score for this RNA gene is

5

Aliases for SNORA50D Gene

  • Small Nucleolar RNA, H/ACA Box 50D 2 3 5

External Ids for SNORA50D Gene

Previous GeneCards Identifiers for SNORA50D Gene

  • GC00U936770
  • GC05U902807

Summaries for SNORA50D Gene

GeneCards Summary for SNORA50D Gene

SNORA50D (Small Nucleolar RNA, H/ACA Box 50D) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA50D Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA76: ACA62 (SNORA76) is a member of the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis [2]. ACA62 is proposed to guide the pseudouridylation of 18S rRNA U34 and U105 [2].

  • Small nucleolar RNA SNORA50: ACA50 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

Additional gene information for SNORA50D Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA50D Gene

Genomics for SNORA50D Gene

Regulatory Elements for SNORA50D Gene

Enhancers for SNORA50D Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H069188 1.1 ENCODE 12.1 +28.9 28919 2.4 PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF207 CDK7 CCDC125 SLC30A5 CCNB1 SNORA50D GTF2H2C MARVELD2 PIR48224 MRPS36
GH05H069093 1.1 ENCODE 11.8 -66.4 -66363 2.4 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 GTF2H2C SNORA50D CCNB1 CENPH SLC30A5 OCLN SMN2 ENSG00000248664
GH05H069105 1 Ensembl ENCODE 12.1 -54.3 -54345 1.4 HDGF ARNT BATF ZIC2 FOSL1 POLR2A ADNP SMARCE1 ZNF362 SOX6 SNORA50D CCNB1 CENPH CDK7 SMN2 OCLN SLC30A5 ENSG00000248664
GH05H069233 1.1 ENCODE 10.6 +74.1 74111 2.2 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF143 CCDC125 SLC30A5 GTF2H2C CDK7 ENSG00000198237 ENSG00000254701 CENPH CCNB1 SNORA50D SMN2
GH05H069213 0.9 ENCODE 11.2 +53.1 53143 0.2 ELF3 ARID4B ZNF366 FOS ATF7 CREM CEBPB TGIF2 MTA1 SMARCA4 CDK7 CENPH CCNB1 SNORA50D MRPS36 PIR48224
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA50D on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA50D Gene

Genomic Locations for SNORA50D Gene
chr5:69,160,806-69,160,939
(GRCh38/hg38)
Size:
134 bases
Orientation:
Plus strand
chr5:68,456,633-68,456,766
(GRCh37/hg19)

Genomic View for SNORA50D Gene

Genes around SNORA50D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA50D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA50D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for SNORA50D Gene

ORGUL Member Location for SNORA50D gene

No data available for RefSeq DNA sequence for SNORA50D Gene

Proteins for SNORA50D Gene

Post-translational modifications for SNORA50D Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA50D Gene

Domains & Families for SNORA50D Gene

Gene Families for SNORA50D Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA50D: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA50D Gene

Function for SNORA50D Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA50D Gene

Localization for SNORA50D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA50D Gene

Pathways & Interactions for SNORA50D Gene

SuperPathways for SNORA50D Gene

No Data Available

Interacting Proteins for SNORA50D Gene

Gene Ontology (GO) - Biological Process for SNORA50D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA50D Gene

Drugs & Compounds for SNORA50D Gene

No Compound Related Data Available

Transcripts for SNORA50D Gene

mRNA/cDNA for SNORA50D Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA50D Gene

No ASD Table

Relevant External Links for SNORA50D Gene

GeneLoc Exon Structure for
SNORA50D
ECgene alternative splicing isoforms for
SNORA50D

Expression for SNORA50D Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA50D Gene

Orthologs for SNORA50D Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA50D Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SNORA50 34
  • 81 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SNORA50 34
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23786 34
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA50 34
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA50 34
  • 42 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA50 34
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORA50 34
  • 54 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii SNORA50 34
  • 56 (a)
OneToOne
Species where no ortholog for SNORA50D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA50D Gene

ENSEMBL:
Gene Tree for SNORA50D (if available)
TreeFam:
Gene Tree for SNORA50D (if available)

Paralogs for SNORA50D Gene

No data available for Paralogs for SNORA50D Gene

Variants for SNORA50D Gene

Relevant External Links for SNORA50D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA50D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA50D Gene

Disorders for SNORA50D Gene

Relevant External Links for SNORA50D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA50D

No disorders were found for SNORA50D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA50D Gene

Publications for SNORA50D Gene

  1. An updated human snoRNAome. (PMID: 27174936) Jorjani H … Gruber AR (Nucleic acids research 2016) 2 3 60
  2. A computational screen for mammalian pseudouridylation guide H/ACA RNAs. (PMID: 16373490) Schattner P … Lowe TM (RNA (New York, N.Y.) 2006) 1
  3. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1
  4. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 1

Products for SNORA50D Gene

Sources for SNORA50D Gene

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