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Aliases for SNORA45B Gene

Subcategory (RNA class) for SNORA45B Gene

snoRNA

Quality Score for this RNA gene is

11.2

Aliases for SNORA45B Gene

  • Small Nucleolar RNA, H/ACA Box 45B 2 3
  • Small Nucleolar RNA, H/ACA Box 45 2 3
  • ACA3-2 SnoRNA 3
  • SNORA45 3
  • ACA3-2 3

External Ids for SNORA45B Gene

Previous HGNC Symbols for SNORA45B Gene

  • SNORA45

Summaries for SNORA45B Gene

Entrez Gene Summary for SNORA45B Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA45B Gene

SNORA45B (Small Nucleolar RNA, H/ACA Box 45B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA45B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Small nucleolar RNA SNORA3/SNORA45 family: The members of this family belong to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines [1]. This family includes mouse snoMBI-28 and human homologues ACA3 (SNORA3) and ACA3-2 (SNORA45). Both ACA3 and ACA3-2 share the same host gene [3]. MBI-28, ACA3 and ACA3-2 are all predicted to guide the pseudouridylation of residues in 28S rRNA [1,2,3].

View fRNAdb secondary structures for SNORA45B

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA45B Gene

Genomics for SNORA45B Gene

Genomic Location for SNORA45B Gene

Start:
8,685,439 bp from pter
End:
8,685,569 bp from pter
Size:
131 bases
Orientation:
Plus strand

Genomic View for SNORA45B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA45B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA45B Gene

ORGUL Member Location for SNORA45B Gene

ORGUL Member Location for SNORA45B gene

No data available for Regulatory Elements for SNORA45B Gene

Proteins for SNORA45B Gene

Post-translational modifications for SNORA45B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA45B Gene

Domains for SNORA45B Gene

Gene Families for SNORA45B Gene

HGNC:
  • SNORA :ncRNAs / Small nucleolar RNAs : H/ACA box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA45B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA45B Gene

Function for SNORA45B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA45B Gene

Localization for SNORA45B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA45B Gene

Pathways for SNORA45B Gene

SuperPathways for SNORA45B Gene

No Data Available

Interacting Proteins for SNORA45B Gene

Gene Ontology (GO) - Biological Process for SNORA45B Gene

None

No data available for Pathways by source for SNORA45B Gene

Transcripts for SNORA45B Gene

fRNAdb Secondary structures for SNORA45B Gene

  • FR229415

mRNA/cDNA for SNORA45B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA45B Gene

No ASD Table

Relevant External Links for SNORA45B Gene

GeneLoc Exon Structure for
SNORA45B
ECgene alternative splicing isoforms for
SNORA45B

Expression for SNORA45B Gene

mRNA expression in normal human tissues for SNORA45B Gene

genes like me logo Genes that share expressions with SNORA45B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SNORA45B Gene

Orthologs for SNORA45B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA45B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA3 36
  • 66 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia SNORA3 36
  • 88 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm25539 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA3 36
  • 75 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA3 36
  • 73 (a)
ManyToMany
SNORA3 36
  • 73 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA3 36
  • 64 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA3 36
  • 69 (a)
ManyToMany
SNORA3 36
  • 68 (a)
ManyToMany
SNORA3 36
  • 62 (a)
ManyToMany
SNORA3 36
  • 70 (a)
ManyToMany
Species with no ortholog for SNORA45B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA45B Gene

ENSEMBL:
Gene Tree for SNORA45B (if available)
TreeFam:
Gene Tree for SNORA45B (if available)

Paralogs for SNORA45B Gene

No data available for Paralogs for SNORA45B Gene

Variants for SNORA45B Gene

Relevant External Links for SNORA45B Gene

HapMap Linkage Disequilibrium report
SNORA45B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SNORA45B Gene

Disorders for SNORA45B Gene

No disorders were found for SNORA45B Gene.

No data available for UniProtKB/Swiss-Prot for SNORA45B Gene

Publications for SNORA45B Gene

  1. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu A.D. … Qu L.H. (Nucleic Acids Res. 2005) 2 3
  2. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for SNORA45B Gene

Sources for SNORA45B Gene

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