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Aliases for SNORA45A Gene

Subcategory (RNA class) for SNORA45A Gene

snoRNA

Quality Score for this RNA gene is

11.4

Aliases for SNORA45A Gene

  • Small Nucleolar RNA, H/ACA Box 45A 2 3
  • Small Nucleolar RNA, H/ACA Box 3 2 3
  • ACA3 Small Nucleolar RNA 3
  • ACA3 SnoRNA 3
  • SNORA3 3
  • ACA3 3

External Ids for SNORA45A Gene

ORGUL Members for SNORA45A Gene

Previous HGNC Symbols for SNORA45A Gene

  • SNORA3

Summaries for SNORA45A Gene

GeneCards Summary for SNORA45A Gene

SNORA45A (Small Nucleolar RNA, H/ACA Box 45A) is an RNA Gene, and is affiliated with the snoRNA class. Among its related pathways are CFTR translational fidelity (class I mutations).

fRNAdb sequence ontologies for SNORA45A Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA3/SNORA45 family: The members of this family belong to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines [1]. This family includes mouse snoMBI-28 and human homologues ACA3 (SNORA3) and ACA3-2 (SNORA45). Both ACA3 and ACA3-2 share the same host gene [3]. MBI-28, ACA3 and ACA3-2 are all predicted to guide the pseudouridylation of residues in 28S rRNA [1,2,3].

View fRNAdb secondary structures for SNORA45A

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA45A Gene

Genomics for SNORA45A Gene

Genomic Location for SNORA45A Gene

Start:
8,684,227 bp from pter
End:
8,684,356 bp from pter
Size:
130 bases
Orientation:
Plus strand

Genomic View for SNORA45A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA45A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA45A Gene

ORGUL Member Location for SNORA45A Gene

ORGUL Member Location for SNORA45A gene

No data available for Regulatory Elements for SNORA45A Gene

Proteins for SNORA45A Gene

Post-translational modifications for SNORA45A Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA45A Gene

Domains for SNORA45A Gene

Gene Families for SNORA45A Gene

HGNC:
  • SNORA :ncRNAs / Small nucleolar RNAs : H/ACA box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA45A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA45A Gene

Function for SNORA45A Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA45A Gene

Localization for SNORA45A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA45A Gene

Pathways for SNORA45A Gene

genes like me logo Genes that share pathways with SNORA45A: view

Pathways by source for SNORA45A Gene

1 BioSystems pathway for SNORA45A Gene

Interacting Proteins for SNORA45A Gene

Gene Ontology (GO) - Biological Process for SNORA45A Gene

None

Transcripts for SNORA45A Gene

fRNAdb Secondary structures for SNORA45A Gene

  • AJ609428
  • DQ571589
  • RF00334;SNORA3;DAAB012419114.1/45-122
  • FR062441

mRNA/cDNA for SNORA45A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA45A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA45A Gene

No ASD Table

Relevant External Links for SNORA45A Gene

GeneLoc Exon Structure for
SNORA45A
ECgene alternative splicing isoforms for
SNORA45A

Expression for SNORA45A Gene

mRNA expression in normal human tissues for SNORA45A Gene

genes like me logo Genes that share expressions with SNORA45A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SNORA45A Gene

Orthologs for SNORA45A Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA45A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA3 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA3 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA3 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm24698 36
  • 87 (a)
OneToMany
Snora3 16
Snora3 36
  • 85 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA3 36
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA3 36
  • 73 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA3 36
  • 72 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA3 36
  • 72 (a)
ManyToMany
SNORA3 36
  • 69 (a)
ManyToMany
SNORA3 36
  • 71 (a)
ManyToMany
Species with no ortholog for SNORA45A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA45A Gene

ENSEMBL:
Gene Tree for SNORA45A (if available)
TreeFam:
Gene Tree for SNORA45A (if available)

Paralogs for SNORA45A Gene

No data available for Paralogs for SNORA45A Gene

Variants for SNORA45A Gene

Relevant External Links for SNORA45A Gene

HapMap Linkage Disequilibrium report
SNORA45A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SNORA45A Gene

Disorders for SNORA45A Gene

No disorders were found for SNORA45A Gene.

No data available for UniProtKB/Swiss-Prot for SNORA45A Gene

Publications for SNORA45A Gene

  1. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3
  2. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  4. Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. (PMID: 9047361) Ofengand J. … Bakin A. (J. Mol. Biol. 1997) 3

Products for SNORA45A Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA45A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA45A
    • Block miRNA regulation of SNORA45A using miScript Target Protectors

    Sources for SNORA45A Gene

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